Nitrocor tabs 0.5mg #40
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Nitrocor instruction for useYou can buy Nitrocor on this pageComposition1 tablet contains:active ingredient: nitroglycerin with lactose 0.5 mg (in terms of 100% substance - 0.5 mg);excipients: potato starch, stearic acid, colloida..
Nitrocor instruction for use
You can buy Nitrocor on this page
1 tablet contains:
active ingredient: nitroglycerin with lactose 0.5 mg (in terms of 100% substance - 0.5 mg);
excipients: potato starch, stearic acid, colloidal silicon dioxide, croscarmellose sodium salt, aspartame, microcrystalline cellulose.
Peripheral vasodilator with a predominant effect on the venous vessels. The action of nitroglycerin is associated mainly with a decrease in myocardial oxygen demand due to a decrease in preload (dilation of peripheral veins and a decrease in blood flow to the right atrium) and an afterload (decrease in total peripheral vascular resistance).
It has a central inhibitory effect on the sympathetic vascular tone, inhibits the vascular component of the formation of pain syndrome. Causes expansion of meningeal vessels, which explains the headache in its application. When using the drug under the tongue, an attack of stenocardia is usually stopped after 1.5 minutes, the hemodynamic and antianginal effect lasts from 30 to 60 minutes.
Quickly and completely absorbed from the surface of the mucous membranes. When taking the drug under the tongue in a dose of 0.5 mg
Nitroglycerin immediately enters the systemic circulation, bioavailability is 100%. The maximum plasma concentration is reached after 5 minutes. The drug has a large volume of distribution. Communication with plasma proteins is 60%.
Indications for use
Relief and short-term prophylaxis of angina attacks.
Contraindications for Nitrocor
Hypersensitivity to nitrates, shock, collapse, age up to 18 years (efficacy and safety have not been established for ages younger than 18 years), lactose intolerance, lactase deficiency, glucose-galactose malabsorption syndrome and phenylketonuria.
With caution (comparing risk and benefit): simultaneous administration of phosphodiesterase 5 inhibitors (sildenafil, tadalafil, vardenafil, etc.), cranial hypertension, cardiac tamponade, uncontrolled hypovolemia, in patients with heart failure with normal or low pulmonary artery pressure, arterial hypotension (systolic blood pressure less than 90 mmHg), angle-closure glaucoma with high intraocular pressure, severe anemia, hyperthyroidism, toxic pulmonary edema, subarachnoid hemorrhage Recent trauma to the head, hemorrhagic stroke, conditions accompanied by a decrease in the filling pressure of the left ventricle (acute myocardial infarction, isolated mitral stenosis, constrictive pericarditis), idiopathic hypertrophic subaortic stenosis, impaired cerebral circulation, severe renal failure, or hepatic insufficiency, renal failure / or hepatic failure, severe renal failure, or hemorrhagic subaortic stenosis, impaired cerebral circulation, severe renal failure, or hepatic insufficiency, renal failure / or hepatic failure, severe renal failure, or hemorrhagic subaortic stenosis, impaired cerebral circulation, severe renal failure, or hepatic insufficiency, renal failure, or hemorrhagic subaortic stenosis, impaired cerebral circulation, severe renal failure, or hepatic insufficiency, renal failure, or hemorrhagic subaortic stenosis, impaired cerebral circulation, severe renal failure, or hepatic insufficiency, renal failure, or hemorrhagic subaortic stenosis; methemoglobinemia).
Pregnancy and lactation
Use during pregnancy and during breastfeeding is possible only for health reasons.
Dosage and administration
Nitrocor is recommended for use as prescribed by a physician.
Nitrocor should be taken immediately at the first signs of an angina attack:
1 tablet of Nitrocor is put under the tongue and held until completely dissolved, without swallowing. The usual dose of the drug - 1 tablet under the tongue.
If an angina attack is not stopped within 5 minutes, you must take another 1 tablet of Nitrocor.
In the absence of a therapeutic effect after taking 2 tablets, you must call a doctor.
With frequent attacks of stenocardia, it is advisable to use prolonged nitroglycerin preparations.
On the part of the central nervous system: blurred vision, "nitrate" headache (especially at the beginning of the course of treatment, with continued therapy decreases), dizziness and a feeling of weakness, anxiety, psychotic reactions, lethargy, disorientation.
Since the cardiovascular system: lower blood pressure; tachycardia, rarely (especially in case of overdose) - orthostatic collapse, cyanosis, facial flushing.
On the part of the gastrointestinal tract: dry mouth, nausea, vomiting, abdominal pain.
Allergic reactions, hypothermia.
Symptoms: decrease in blood pressure (below 90 mm Hg) with orthostatic disregulation, severe dizziness, headache, fainting, shortness of breath, severe weakness, rapid heartbeat, fever, cramps, asthenia, drowsiness. When using high doses (more than 20 mcg / kg) - collapse, cyanosis, methemoglobinemia, dyspnea and tachypnea.
If symptoms of overdose appear, immediately lay down the patient, lift the legs and immediately call a doctor.
The hypotensive effect of the drug might be excessive in the case of uncontrolled simultaneous reception vasodilators, antihypertensives, angiotensin converting enzyme (ACE) inhibitors, phosphodiesterase inhibitors, blockers "slow" calcium channel blockers, tricyclic antidepressants, alcohol, diuretics, beta-blockers, monoamine oxidase (MAO) inhibitors procainamide.
Appointment with dihydroergotamine can lead to an increase in its content in the blood and high blood pressure (due to increased bioavailability of dihydroergotamine).
The simultaneous appointment of Nitrocor and heparin reduces the effectiveness of the latter (after discontinuation of the drug, a significant decrease in blood clotting is possible, which may require lowering the dose of heparin).
Special instructions for Nitrocor
While taking Nitrocor tablets, a significant reduction in blood pressure and the appearance of dizziness may occur with a sudden transition to a vertical position from a sitting or lying position; when drinking alcohol, performing physical exercises and hot weather. To Nitrocor, as well as to other organic nitrates, with frequent use may develop addiction, requiring an increase in dosage.
If blurred vision or dry mouth persists or is severe, treatment should be stopped.
The severity of headache while taking Nitrocor can be reduced by lowering its dose and / or by simultaneously taking validol.
Influence on ability to drive a vehicle
When driving vehicles and controlling mechanisms that require increased attention, it should be borne in mind that taking Nitrocor can lead to a decrease in motor and mental response.
On 40 tablets in a test tube glass or polymeric with a polyethylene stopper.
On one test tube together with the application instruction is placed in a pack from a cardboard.
In the dark place at a temperature not exceeding 25 ° C, away from fire.
Keep out of the reach of children.
Shelf life - 2 years.
The drug should not be used after the expiration date.
Pharmacy sales terms
A prescription is not required to buy Nitrocor.