Akriderm GK ointment 30gr

Instruction for Akriderm GK

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Composition

The composition of the drug includes active substances: betamethasone dipropionate, clotrimazole and gentamycin sulfate.
Additional components: Vaseline, propylene glycol, vaseline oil, cetostearyl alcohol, cetostearyl ester of macrogol, Trilon B, sodium dihydrogen phosphate dihydrate and purified water.

Form of issue

Issue Akriderm GK in the form of a cream or ointment for external application, packaged in tubes of 15 and 30 g.

pharmachologic effect

Each form of the drug has anti-inflammatory, anti-allergic, antibacterial and antifungal effect.

Pharmacodynamics and pharmacokinetics

The effect of this combination drug is due to its constituents, which are a glucocorticosteroid, an antibiotic-aminoglycoside and an antifungal agent.
The use of betamethasone dipropionate helps inhibit the concentration of leukocytes, the formation of lysosomal enzymes and a number of anti-inflammatory mediators in the field of inflammation. In this case, oppression of phagocytosis occurs, a decrease in vascular-tissue permeability and a prevention of the onset of inflammatory puffiness.
For gentamycin, which is an antibiotic with a broad spectrum of action, which is part of the group of aminoglycosides, a bactericidal effect is characteristic. Its action is directed to the causative agents of many primary, also secondary bacterial infections of the skin, namely: gram-negative and gram-positive bacteria. However, anaerobes, fungi and viruses are not sensitive to this substance.
The antifungal effect of the drug is provided by clotrimazole. At the same time, there is a disruption in the synthesis of ergosterol, which constitutes the cell membrane of fungi.
Activity is manifested in the most common fungi: Trichophyton rubrum, Epidermophyton floccosum, Candida albicans and so on.

Indications for use

The drug Akriderm GK is administered during treatment:
    various dermatoses;
    offshoot lichen;
    neurodermatitis;
    dermatomycosis.

Contraindications

It is not recommended to use a cream or ointment Akriderm GK with:
    hypersensitivity to it;
    skin tuberculosis;
    cutaneous syphilis;
    skin postvaccinal reactions;
    chicken pox;
    simple herpes;
    lactation;
    children under the age of one year;
    external otitis.

Application in pregnancy

How safe to take this drug during pregnancy is not fully established. Therefore, to use an ointment or cream Akriderm GK in this period is possible only when the potential benefit greatly exceeds the possible risk. In any case, preparations of this group should not be used for a long time in elevated dosages.

Side effects

The use of SCS often causes such side effects as: burning, irritation, excessive dry skin, hypertrichosis, folliculitis, acne, hypopigmentation, dermatitis and so on.
Long-term use, especially under occlusive dressings, can cause chalk, maceration or atrophy of the skin, secondary infection, purple.
With the utmost caution, it is necessary to treat children in order to avoid the occurrence of such systemic undesirable effects as hyperglycemia, glucosuria, oppression of the adrenal cortex, Cushing's syndrome and so on.

Instructions for use Akriderm GK (Method and dosage)

Ointment Akriderm GK instructions for use recommends applying only externally. In this case, the agent is applied with a sufficiently thin layer to the lesions of the skin. You need to do this every 2 times.
It should be noted that the instructions for use on the Akriderm GK cream contain the same therapeutic regimen. But it is also possible for the doctor to prescribe an individual treatment, depending on the severity of the disease. Light cases allow the use of the cream only once a day, while the heavier cases, on the contrary, increase the frequency of application.
The duration of therapy usually depends on how effective this remedy turned out to be in a particular case, and can be 2-4 weeks.
If there is a prolonged absence of a positive result, the diagnosis should be specified.

Overdose

The use of this drug rarely leads to the development of acute overdose. However, its long-term use in large quantities does not exclude the occurrence of a chronic overdose accompanied by symptoms of hypercorticism, for example, hyperglycemia, glucosuria, oppression of the adrenal cortex, Cushing's syndrome.
The appearance of undesirable effects requires symptomatic therapy with a gradual withdrawal of the drug.

Interaction

Cases of drug interactions with various drugs have not been identified.

special instructions

The appearance of symptoms of sensitivity, irritation of the skin and other undesirable symptoms that causes the use of the drug, requires the abandonment of this therapy and the choice of another suitable means.
Long-term treatment, application of cream or ointment on extensive skin surfaces, the use of occlusive dressings and therapy of children can cause systemic absorption of GCS.
This external product can be used in the treatment of children from year to year, but only on the recommendation and under the careful supervision of a specialist, which will avoid the occurrence of systemic side effects. It has been established that the application of the cream or ointment Akriderm GK for a long time to extensive areas leads to oppression of the hypothalamic-pituitary-adrenal system, hypercorticism, a decrease in growth hormone excretion and an increase in intracranial pressure.
In addition, with prolonged application on the face often there are atrophic changes, compared with other areas of the skin. For this reason, a standard therapeutic course should be followed, which is 5 days.
It is contraindicated to use any form of the drug in ophthalmology, avoiding its accidental exposure not only to the eyes, but also the mucous membranes.

Terms of sale

The prescription is not requered when you buy Akriderm GK.

Storage conditions

The drug is stored at room temperature, 15-25 ° C, in a place inaccessible to children.
Shelf life - 2 years.

Reviews about Akriderm GK

According to many users, this external tool is one of the most effective. Although reviews on the cream of Akriderm GK are more common than ointments. In any case, each of the forms of this drug is prescribed to treat a variety of skin diseases and usually within a couple of days the patients notice an improvement.
It should be noted that in addition to positive feedback, one can also find reports on the development of side effects. Usually, symptoms that indicate intolerance or sensitivity of this drug are described: increased redness, peeling, inflammation and so on.
In addition, patients often report that the drug helps, only while you use it, and soon after the withdrawal symptoms return.
The reason for this is, most likely, that Akriderm GK helps to suppress manifestations of the disease, but the disease itself still does not work. Therefore, in addition to the drug that facilitates the patient's condition, in addition, the main treatment of the source of the health disorder should be carried out.
In any case, use this tool without the appointment of a specialist is not recommended. In addition to the fact that therapy may be simply useless, it is possible that the most severe complications that usually require long-term treatment are not ruled out.