Daivobet ointment 30gr

Daivobet user manual

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Composition

In the composition of Daivobet ointment intended for external use, active components such as betamethasone dipropionate (0.643 mg) and calcipotriol monohydrate (0.052 mg) are contained.
In the preparation, liquid, as well as white paraffin (mild), alpha-tocopherol and polypropylene glycol stearate are used as auxiliary compounds.

Form of issue

The ointment has a uniform consistency, it can be white or yellowish in color. The medical device is packed in lacquered inside aluminum tubes, equipped with a lid, nominal volume of 15, 30, and 60 g. This carton contains one tube with the drug and instruction.

pharmachologic effect

Daivobet refers to glucocorticoid drugs, which exerts on the human body a pronounced antipsoriatic and anti-inflammatory effect.
In addition, the drug is characterized as a D-vitamin-like drug.

Pharmacodynamics and pharmacokinetics

The synthetic analogue of the metabolite of vitamin D, calcipotriol, which is part of the Daivobet, accelerates the morphological differentiation of keratinocytes and slows down their proliferation. GCS (glucocorticosteroid) in the form of betamethasone has a local antipruritic, vasoconstrictive, anti-inflammatory, as well as immunosuppressive effects on the body.
When applying the drug to the affected areas of the skin with psoriasis, using occlusive dressings, the absorption of the active drug components of the drug is greatly enhanced. Betamethasone is excreted through the intestines and kidneys. The active component is metabolized in the kidneys and liver with the associated formation of sulfoesters and glucuronides.

Indications for use

Daivobet is used in the therapeutic treatment of psoriasis (chronic, plaque).

Contraindications

It is not recommended to use a medical product in the treatment of patients with hypersensitivity to the active components of the drug, in the presence of liver and kidney diseases, with pustular, guttate and exfoliative psoriasis, with psoriasis-like erythroderma, as well as in viral, parasitic, bacterial and fungal skin lesions smallpox, perioral dermatitis, rosacea, acne, syphilis, tuberculosis, herpes, ulcers, ichthyosis, atrophy of the skin, fragility of the vessels, genital and perianal itching).
In addition, Daivobet is contraindicated in patients under the age of 18 years.

Side effects

When applying Daivobet, you may be concerned with: burning, skin irritations, dermatitis, erythema, exacerbation of psoriasis, folliculitis, itching, pigmentation at the site of application, rash, pustular psoriasis. With a sufficiently long application of a medical device, atrophy of the skin, striae, hypertrichosis, telangiectasias, dermatitis, skin degeneration, pustular psoriasis, photosensitivity, edema can develop.
In addition, there may be such systemic reactions to the drug as: Itenko-Cushing's syndrome, hypercalciuria, hypercalcemia, adrenal insufficiency and hypercorticism.

Instructions for Daivobet (Method and Dosage)

Daivobet is intended for external use, it should be applied in a thin layer to affected areas of the skin, not more than once a day. The recommended daily dose is 15 g, but not more than 100 g per week. As a rule, the course of therapeutic treatment with a drug does not exceed one month.
The medical device can be used repeatedly after a short break, under the obligatory supervision of the doctor. It is important to remember that the total area of ​​application of the drug to the skin should not exceed 30% of the surface of the human body.

Overdose

As a rule, the symptoms of an overdose of Daivobet are considered to be an increase in the level of calcium in the blood plasma, as well as adrenal insufficiency.

Storage conditions

It is important to keep the medicine away from children, at a temperature not exceeding 25 ° C.

Shelf life

The total shelf life of the drug is 2 years, but after opening the aluminum tube with ointment, Daivobet can only be used for 6 months.

special instructions

It is forbidden to apply ointment on the face, scalp or mucous membrane, and also on the periorbital area.
After using Daivobet it is recommended to wash your hands thoroughly with soap and water.
Since the drug contains highly active GCS (basic drug components), it is not recommended to use similar medications simultaneously with Daivobet.
During treatment with the drug, patients should avoid prolonged exposure to natural or artificial sunlight. It is not recommended to apply Daivobet for a long period of time. The medical device does not affect the patient's ability to drive or work with potentially dangerous mechanisms.

Children

The medication is not used in the treatment of patients under the age of 18 years.

In pregnancy and lactation

Guided by general recommendations, you should not use ointment in the treatment of pregnant or lactating women. However, a doctor can appoint a Daivobet to a patient only if the intended benefit will substantially exceed the possible harm to the health of the mother and child.

Reviews of Daivobet

On the Internet, you can find different reviews about Daivobet. Some patients are satisfied with the effectiveness of the drug, but there are also those who are negative about the ointment, not only noting its inefficiency, but also an extensive list of side effects.