Exoderil solution 1% 30ml

Exoderil solution user manual

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Release form, composition and packaging

Solution for external use transparent, colorless or slightly yellow in color, with the smell of ethanol.
1 ml
Naftifine hydrochloride 10 mg
Excipients: propylene glycol - 50 mg, ethanol - 400 mg, purified water - 475 mg.

pharmachologic effect

Antifungal drug for external use of the group allylaminov. The mechanism of action is associated with inhibition of the synthesis of squalene-2,3-epoxidase, which leads to a decrease in the formation of ergosterol, which is part of the cell wall of the fungus.
Exoderil solution is active against dermatophytes Trichophyton, Epidermophyton, Microsporum, yeast (Candida spp., Pityrosporum), mold fungi (Aspergillus spp.) And other fungi (Sporotrix schenckii). With respect to dermatophytes and aspergillus, naftifine is fungicidal. In relation to yeast fungi, it exhibits fungicidal or fungistatic activity depending on the strain of the microorganism. The drug has an antibacterial effect against gram-positive and gram-negative microorganisms that can cause secondary bacterial infections.
Exoderil solution has an anti-inflammatory effect, which contributes to the rapid disappearance of the symptoms of inflammation, especially itching.

Pharmacokinetics

Naftifine quickly penetrates the skin, creating stable antifungal concentrations in its different layers, which makes it possible to use it once a day.

Indications for Exoderil solution

- fungal infections of the skin and skin folds (tinea corporis, tinea inguinalis), incl. interdigital mycoses (tinea manum, tinea pedum);
- fungal infections of the nails (onychomycosis);
- candidiasis of the skin;
- pityriasis versicolor;
- dermatomycosis (with or without itching).
Solution Exoderil is effective in treating mycoses affecting the skin area with hyperkeratosis, as well as in the hair growth zone.

Contraindications for Exoderil solution

- pregnancy (safety and efficacy not determined);
- lactation period (safety and efficacy not determined);
- Hypersensitivity to naftifine or propylene glycol.
Application of the drug on the wound surface is contraindicated.
With care: children's age (experience of clinical use is limited).

Dosage

Exoderil solution should be applied to the affected surface of the skin and adjacent areas 1 time / day, after thorough cleaning and drying, capturing approximately 1 cm of healthy skin at the edges of the affected area.
The duration of treatment for ringworms is 2-4 weeks (up to 8 weeks if necessary), and candidiasis 4 weeks.
For onychomycosis, before the first application of the solution, it is necessary to remove the affected part of the nail as much as possible with scissors and a nail file. Exoderil solution should be used 2 times / day, the duration of treatment - up to 6 months.
To prevent recurrence of infection, therapy should be carried out for at least 2 weeks after the disappearance of the clinical symptoms.

Side effects

Local reactions: in some cases - dry skin, redness, burning.
Side effects are reversible and do not require discontinuation of therapy.

Overdose

No cases of overdose have been reported.

Drug interaction

No marked drug interaction Exoderil solution with other drugs.

special instructions

The drug is not intended for use in ophthalmology. Avoid contact with eyes.
No special measures for the destruction of the drug.

Influence on ability to drive motor transport and control mechanisms

The drug does not adversely affect the ability to drive vehicles and perform other activities that require concentration of attention and speed of psychomotor reactions.

Pregnancy and lactation

Use of the drug Exoderil solution during pregnancy and lactation is contraindicated (safety and efficacy not determined).

Use in childhood

With care: children's age (experience of clinical use is limited).

Pharmacy sales terms

You don't need a prescription to buy Exoderil solution.

Terms and conditions of storage

The drug should be stored out of the reach of children at a temperature not higher than 30 ° C. Shelf life - 5 years.