Fungoterbine Neo gel 1% 15gr

Instruction for Fungoterbine Neo

You can buy Fungoterbine Neo here

Release form, composition and packaging

The gel for external use is colorless, transparent or translucent, with a faint odor.
1 g
terbinafine hydrochloride 10 mg
urea 100 mg
Excipients: butylhydroxytoluene (dibunol), carbomer (carbopol), trolamine (thermostable triethanolamine, 2.2I, 2II-nitriloethanol), propylene glycol - up to 1 g.

pharmachologic effect

Antifungal drug for external use. Terbinafine - the active ingredient of the drug Fungoterbine NEO, is an allylamine and has a broad spectrum of antifungal action.
Terbinafine disrupts the early stages of ergosterol biosynthesis in fungi. This leads to a deficiency of ergosterol and to the intracellular accumulation of squalene, which causes the death of the fungal cell. The action of terbinafine is carried out by inhibiting the enzyme squalene epoxidase, located on the cell membrane of the fungus. This enzyme does not belong to the cytochrome P450 system, therefore, terbinafine does not affect the metabolism of hormones or other drugs.
Terbinafine has a fungicidal effect against dermatophytes, molds and some dimorphic fungi. Activity against yeast-like fungi, depending on their species, may be fungicidal or fungistatic.
Urea is the second active ingredient Fungoterbine NEO, has a soothing, exfoliating and moisturizing effect, it can increase dermatopenetrantness (penetration into the skin) and create high concentrations of terbinafine in the skin. Urea helps to bind water and soften the stratum corneum.

Pharmacokinetics

With topical application of the gel, less than 5% of terbinafine is absorbed, thus, the systemic effect of Fungoterbine Neo is minimal. The drug quickly penetrates the skin and accumulates in the sebaceous glands.

Indications for Fungoterbine Neo

Treatment and prevention of fungal diseases:
- fungal infections of the skin caused by dermatophytes such as Trychophyton (for example, T.rubrum, T.mentagrophytes, T.verrucosum, T.violaceum), Microsporum canis and Epidermophyton floccosum.
- skin infections caused by yeast-like fungi of the genus Candida (for example, Candida albicans).
- versicolor versicolor (Pityrosporum versicolor), caused by Pityrosporum orbiculare (also known as Malassezia furfur).

Contraindications

- hypersensitivity to Fungoterbine Neo;
- children's age (up to 2 years).
With care: liver and / or kidney failure, alcoholism, blood diseases, tumors, metabolic diseases, vascular pathology of limbs, pregnancy, lactation.

Dosage

Outwardly. The drug is applied to the skin once or twice a day. The gel is applied in a thin layer on the affected skin and lightly rubbed. To improve the effectiveness of treatment may use occlusive dressings. For infections with diaper rash (under the mammary glands, in the interdigital spaces, between the buttocks, in the inguinal region), the place of application of the gel can be covered with gauze, especially at night.
The average duration and frequency of treatment:
Ringworm of trunk, legs: 1 week 1 time per day.
Ringworm stop: 1 week 1 time per day.
Skin candidiasis: 1-2 weeks 1 or 2 times a day.
Multi-colored lichen: 1 week 1 or 2 times a day.

Side effects of Fungoterbine Neo

In rare cases, redness of the skin, a sensation of itching or a burning sensation may occur at the site of application of the gel, however, these phenomena rarely led to the need to discontinue treatment. The above symptoms should be distinguished from allergic reactions, for example, urticaria, which occur rarely, however, when they appear, it is necessary to stop treatment.

Overdose

No cases of drug overdose have been reported. If, by chance, Fungoterbine Neo is ingested, you can expect the development of the same side effects as overdose of Fungoterbine tablets: nausea, anorexia, pain in the upper abdomen, diarrhea.

Drug interaction

Any drug interactions when using terbinafine is not known externally.

special instructions

Reducing the severity of clinical manifestations is usually observed in the first days of treatment. In the case of irregular treatment or its premature termination, there is a risk of re-infection. If after two weeks of treatment there are no signs of improvement, the diagnosis should be verified.
The gel is intended for external use only. Avoid contact with the eyes and mucous membranes, because Fungoterbine Neo may cause irritation. In case of accidental ingestion of the drug in the eyes, they should be immediately washed with running water, and in the case of persistent irritation, you should consult with your doctor.

Pregnancy and lactation

In experimental studies, the teratogenic properties of terbinafine have not been identified. Use of Fungoterbine Neo during pregnancy is possible in cases where the potential benefit to the mother outweighs the risk to the fetus. It is used with caution during lactation.

Use in childhood

Contraindicated in children under 2 years.

In case of impaired renal function

With caution in renal failure

With abnormal liver function

With caution in liver failure

Pharmacy sales terms

You can buy Fungoterbine Neo without a prescription.

Terms and conditions of storage

Store at a temperature not exceeding 20 ° C. Keep out of the reach of children. Shelf life - 2 years.