Klenzit-C user manual
You can buy Klenzit-C here
Composition
1 gram of gel contains 1 mg of Adapalene + 10 mg of Clindamycin - the active substances.
Auxiliary Ingredients:
propylene glycol;
disodium edetate;
methylparahydroxybenzoate;
carbomer 940 (carbopol 940);
phenoxyethanol;
sodium hydroxide;
poloxamer 407;
purified water.
Form of issue
Klenzit-C is available in the form of a gel for external use.
The package contains 1 tube of 1 mg + 10 mg / 1 g of gel per 15 g or 30 g.
pharmachologic effect
Anti-inflammatory, comedonolytic, bacteriostatic.
Pharmacodynamics and pharmacokinetics
Gel Klenzit-C is a combined medicine for the treatment of acne (acne), topical application. Active substances are Adapalen and Clindamycin.
The retinoid derivative, Adapalene, exhibits anti-inflammatory and comedonolytic activity. Has an influence on open and closed comedones, contributes to the normalization of the processes of epidermal differentiation and keratinization. The drug reduces the binding time of follicular cells of the epithelium, which promote the formation of micro-medones, and also inhibits chemokinetic reactions and chemotaxis of polynucleotide cells.
Antimicrobial Clindamycin belongs to the group of lincosamides and has bacteriostatic activity against many microorganisms. Clindamycin binding to the 50S subunit of ribosomal membranes, inhibits the replication of the protein in the bacterial cell. It also exhibits bactericidal action against certain gram-positive cocci.
In the therapy conducted with the use of ClenSite C, in patients with acne it is noted a decrease in the intensity of inflammation, a decrease in acne, as well as a decrease in the number of comedones and a general improvement in the skin condition of the face.
In connection with the external application of the drug Clenzite With its systemic absorption is negligible.
Indications for use
Treatment of acne (acne).
Contraindications
hypersensitivity to Adapalen, Clindamycin and other ingredients of the drug;
lactation period;
period of pregnancy.
Use with caution in eczema and dermatitis.
Side effects
Treatment with the use of gel Klenzit-C basically passes without any serious complications. In some patients, rarely observed hyperemia, irritation, peeling of the skin. In such cases, it is recommended to temporarily suspend therapy and continue treatment after the disappearance of these side effects.
At the beginning of the course of treatment, sometimes there may be an aggravation of acne that takes place in the further treatment process.
Single cases of the development of allergic manifestations, which serve as indications for the complete withdrawal of treatment, are described.
Instructions for use (Method and dosage)
Klenzit-C in the form of a gel is intended for external (local) use.
Directly before applying the gel, the instructions for use recommend cleaning and drying the problem areas of the facial skin. The drug is applied with dot smears without rubbing or using on skin areas with damaged integrity and / or burns.
Apply gel recommended before bedtime. When applied in the daytime, it should be for the next 1-2 hours, to refrain from applying makeup and washing.
It is necessary to avoid getting medication in the nasal cavity, mouth and eye mucosa.
The duration of the course of therapy and the scheme of application of the drug Klensit C is determined by the attending physician. Depending on the complexity of the course of the disease, 1 or 2 applications per day are prescribed. Following the instructions for Klenzit-C, the average duration of therapy is 14-28 days. It is possible to prescribe a second course of treatment, after consulting with the attending physician.
Overdose
Due to the fact that the Klenzit-C gel is used exclusively externally, its overdose is unlikely.
If you accidentally take the gel inside recommend immediate carrying out of gastric lavage and taking enterosorbent funds.
Interaction
Simultaneously with Klenzit-C, do not use alcohol-containing products, as well as ointments and creams with a drying, irritating effect.
Do not recommend the combined use of Klenzit-C and drugs containing calcium gluconate, aminoglycosides, Ampicillin, magnesium sulfate and vitamin B complex.
Perhaps a joint appointment with Benzoyl peroxide.
Simultaneous application of ClenSite C with Erythromycin leads to a mutual decrease in effectiveness.
Storage conditions
At a temperature of no higher than 25 ° C.
Shelf life - 24 months.
special instructions
At the beginning of the course of therapy with the use of Klenzit-C gel, aggravation of the acne is possible, which itself disappears in the further treatment process.
In case of irritation of the skin, stop applying the gel (temporarily or completely).
It is necessary to avoid the natural or artificial (solarium) ultraviolet radiation. If it is necessary to stay in the sun for a long time, the gel should be applied 24 hours before and after.
The use of gel, on damaged skin, is not allowed.
If the gel gets into the mouth or nose, as well as the eye mucosa, it should be rinsed thoroughly with warm water.
During pregnancy (and lactation)
Gel Klenzit-C is not prescribed for pregnancy and breastfeeding.
Reviews of Klenzit-C
Among the reviews on medicines intended for getting rid of acne, reviews about Klenzit-C, in the absence of contraindications and allergic reactions to its components, are completely positive. The drug has high efficacy with small ongoing side effects, including: redness, peeling of the skin and exacerbation of the disease at the beginning of therapy.
It should be remembered that the use of Klenzit-C gel is recommended for no more than 4 weeks, after which they switch to the use of Clenzite or another similar drug.
