Loceryl 5% 2.5ml

Loceryl instruction for use

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Composition

1 gram 5% of the external solution of Loceryl contains 57.4 mg amorolfin.
Additional substances: methyl methacrylate copolymer, trimethylammonioethyl methacrylate chloride copolymer, ethacrylate copolymer, triacetin, ethyl acetate, butyl acetate, ethanol.

Form of issue

2.5 or 5 ml solution in a dark glass vial - 1 bottle with 16 cleaning swabs, 10 spatulas and 30 nail files for one-time use in a paper box.

pharmachologic effect

Fungistatic, antifungal, fungicidal action.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Loceryl is an antifungal external preparation. The medicine demonstrates a fungicidal and fungistatic effect, which is caused by the destruction of the cytoplasmic membrane of the fungal cell by blocking the synthesis of sterols. Reduced concentration of ergosterol, accumulate atypical non-planar sterols. Has a large spectrum of action.
Oppresses both common and rare species of fungi - causative agents of nail lesions:
    yeast fungi of the genera Malassezia (Pityrosporum), Candida, Cryptococcus;
    dermatophytes of the genera Microsporum, Trichophyton, Epidermophyton;
    fungi of the genera Fonsecaea, Cladopsorium, Wangiella (family Dematiaceae);
    mold fungi of the genera Scopulariopsis, Alternaria, Hendersonula;
    dimorphic fungi of the genera Coccidioides, Histoplasma, Sporothrix.

Pharmacokinetics

After application on the nail plate penetrates into it and into the nail bed. The therapeutic concentration persists for 10 days even after the first application.
Absorption in the systemic circulation is insignificant.

Indications for use

    Therapy of fungal diseases of nails caused by molds and yeast fungi, dermatophytes.
    Prevention of fungal diseases of the nails.

Contraindications

Supersensitivity to the constituents of the agent.

Side effects

In rare cases, it is possible to change the color of the nail, the development of its increased brittleness, which are the result of the fungus's nail damage.
In very rare cases, a brief light burning sensation near the nail after application of the varnish, contact dermatitis, is possible.

Instructions for use Loceryl (Method and dosage)

Instruction on Loceryl indicates that nail polish should be used externally, applying it to the affected nail fungus to twice a week according to the scheme below:
    Before using the drug, if possible, remove the affected areas of the nail plate with a nail file, which is included in the kit;
    then the surface of the nail plate should be cleaned and degreased with a swab from the kit impregnated with alcohol (a similar treatment with a saw and a swab should be done every time before applying the medication);
    the next step is to dip the spatula in the vial with the varnish and take it out, without touching the neck of the vial (it is forbidden to remove excess funds from the neck of the vial);
    nail polish Loceryl is applied to the affected nail on the entire surface with a spatula, repeating this procedure for each sick nail;
    After the vial is tightly closed immediately after application;
    the varnish is allowed to dry (this usually occurs within 3 minutes);
    use a swab to wipe the spatula, avoiding contacting the nail plate and tampon, and throw it away;
    treatment continues until the healing of the affected area and the regeneration of the nail.
The average duration of treatment for the nails on the hands is 6 months and for the nails on the feet -1 year.

Overdose

Due to the lack of systemic absorption, an overdose of the drug is extremely unlikely.

Interaction

There is no data on the characteristics of interaction with other external agents.

Terms of sale

Without recipe.

Storage conditions

Store at room temperature. Keep away from children.
Shelf life - Three years.

special instructions

The saws that were used to treat sick nail plates should not be used to manipulate healthy nails.
Working with solvents of an organic type, persons must wear impermeable gloves to protect their nail polish.
During the treatment with the drug should avoid the use of artificial nail plates and do not apply cosmetic varnish.
The tampon contains an easily flammable component.
It is necessary to avoid penetration of varnish on the ears, eyes and mucous membranes.
Persons with conditions predisposing to the appearance of fungal infections of the nail plate (diabetes mellitus, peripheral circulation disorder, immunodeficiencies), as well as to persons with or destroyed nail or nail dystrophy before using the drug, should consult a doctor.

Children

The drug is not prescribed for children.

In pregnancy and lactation

The use of the drug in these periods is prohibited.

Reviews of Loceryl

Reviews of the varnish Loceryl on the forums are often replete with a lot of negative reviews on the nail polish from the fungus nail Loceryl. The doctors' comments also indicate that the drug is often ineffective. The greatest dissatisfaction is caused by cases of complete absence of therapeutic effect at a high price for this varnish against nail fungus.