Mycoderil cream 1% 15ml

Mycoderil instruction for use

You can buy Mycoderil cream here

Release form, composition and packaging

Cream for external use 1% white, uniform, with a slight specific odor.
1 ml
Naftifine hydrochloride 10 mg
Excipients: sodium hydroxide - 1.2 mg, benzyl alcohol - 10 mg, sorbitan stearate - 19 mg, cetyl palmitate - 20 mg, polysorbate 60 - 61 mg, cetostearyl alcohol - 80 mg, isopropyl myristate - 80 mg, purified water - up to 1000 mg.

pharmachologic effect

Naftifine is an antifungal agent for external use, belonging to the class of allylamines. The mechanism of action is associated with inhibition of squalene-2,3-epoxidase, which leads to a decrease in the formation of ergosterol, which is part of the cell wall of the fungus. It is active against dermatophytes, such as trichophyton, epidermofiton and microsporum, mold (Aspergillus spp.), Yeast fungi (Candida spp., Pityrosporum) and other fungi (for example, Sporothrix schenckii). With respect to dermatophytes and aspergillus, naftifine is fungicidal. In relation to yeast fungi, Mycoderil exhibits fungicidal or fungistatic activity depending on the strain of the microorganism. It has antibacterial activity against gram-positive and gram-negative microorganisms that can cause secondary bacterial infections. It has an anti-inflammatory effect, which contributes to the rapid disappearance of the symptoms of inflammation, especially itching.

Pharmacokinetics

When applied topically, it penetrates well into various layers of the skin, creating stable antifungal concentrations in its various layers. After application to the skin, less than 6% naftifine is subjected to systemic absorption. The absorbed amount is partially metabolized and excreted by the kidneys and through the intestines. T1 / 2 of the drug is 2-3 days.

Indications for Mycoderil cream

- fungal infections of smooth skin and skin folds (tinea corporis, tinea inquinalis);
- interdigital mycoses (tinea manum, tinea pedum);
- fungal infections of the nails (onychomycosis);
- candidiasis of the skin;
- pityriasis versicolor;
- dermatomycosis (with or without itching).

Dosing regimen

Outwardly.
With skin lesions, Mycoderil is applied 1 time / day to the affected skin surface and areas adjacent to it, after thorough cleaning and drying (capturing approximately 1 cm of healthy skin at the edges of the affected area).
The duration of treatment for ringworms is 2-4 weeks (up to 8 weeks if necessary), and candidiasis 4 weeks.
With the defeat of nails, Mycoderil is applied 2 times / day on the affected nail. Before the first use of Mycoderil, remove the affected part of the nail as much as possible with scissors or a nail file.
The duration of therapy for opiochomycosis is up to 6 months.
To prevent relapse, treatment should be continued for at least 2 weeks after the disappearance of the clinical symptoms.

Side effect

Reactions may occur at the site of application: dry skin, skin flushing and burning. Side effects are reversible and do not require discontinuation of treatment. If any of the side effects indicated in the instructions are aggravated, or any other side effects that are not indicated in the instructions are noted, you should immediately inform your doctor.

Contraindications

- hypersensitivity to naftifine, benzyl alcohol or other components of Mycoderil;
- pregnancy and lactation (the safety and efficacy of Mycoderil in this category of patients has not been studied).
With care: children's age (experience of clinical use is limited).

Use during pregnancy and lactation

The use of Mycoderil during pregnancy and lactation is contraindicated (the safety and efficacy of the drug in this category of patients has not been studied).

Use in children

The drug should be used with caution in children and adolescents under the age of 18 years (experience with clinical use is limited).

special instructions

Requires a course of treatment.
Precautions for use: the drug Mycoderil is not intended for use in ophthalmology. Do not allow the drug into the eyes.
Use in pediatrics: the drug should be used with caution in children under 18 years of age (the efficacy and safety of the drug has not been proven).

Influence on ability to drive vehicles and other mechanisms

Mycoderil does not adversely affect the ability to drive vehicles and perform other activities that require concentration of attention and speed of psychomotor reactions.

Overdose

No cases of overdose have been reported.

Drug interaction

Not studied.

Terms and conditions of storage

The drug should be stored out of the reach of children at a temperature not higher than 25 ° C. Shelf life - 2 years.
Do not use after the expiration date printed on the package.

Pharmacy sales terms

You can buy Mycoderil without a prescription.