Thioctacid BV tabs 600mg #30

Thioctacid instruction

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Composition

The tablet contains 600 mg of thioctic acid.
Additional substances: hydroxypropylcellulose, magnesium stearate, low-substituted hydroxypropylcellulose, hypromellose, titanium dioxide, macrogol 6000, quinoline yellow aluminum salt, talc, aluminum salt of indigo carmine - per tablet.
In one ampoule of the drug contains thiectic acid 600 mg (in the form of trometamol salt) + purified water and trometamol.

Form of issue

Tablets in a shell, convex, yellow with a green tint. In bottles of 30 pieces.
The solution for intravenous injections is yellow, transparent. In ampoules of dark glass, 5 pieces each, 24 ml. In a cardboard pack of 5 or 10 ampoules.

pharmachologic effect

Metabolic means.

Pharmacodynamics and pharmacokinetics

Thioctic acid - a powerful antioxidant, belongs to a group of vitamin-like substances. The substance takes part in the reaction of oxidative decarboxylation of pyruvic acid and alpha-keto acids, is a coenzyme of mitochondrial complexes. By effect, the acid is similar to vitamin B. It protects cells from the harmful effects of free radicals, lowers blood glucose levels.
When taking the tablets, the active substance is quickly absorbed and enters the systemic circulation. However, simultaneous intake of food can reduce its concentration. It reaches a maximum value in half an hour, bioavailability of about 70%, half-life half an hour. Metabolized, excreted through the kidneys.

Indications for use

The drug is prescribed for symptomatic treatment:
    sensory-motor diabetic polyneuropathy;
    polyneuropathy caused by alcohol.

Contraindications

Due to the lack of clinical studies and sufficient experience of the use of the drug, it is not recommended to take Tioctacida by pregnant and lactating women, children and adolescents.
Contraindications are allergies to any of the components of the drug.

Side effects

During the reception of tablets may appear:
    allergic reactions (rashes, itching on the skin, hives);
    adverse reactions from the gastrointestinal tract (pain, nausea, diarrhea, vomiting).
Adverse reactions with intravenous administration of the drug:
    skin rash, itching, anaphylactic shock;
    a sharp increase in intracranial pressure, difficulty breathing;
    convulsions, bleeding and minor hemorrhages, problems with vision (rarely).

Instructions for use of Thioctacid (Method and dosage)

Take pills Thioctacid BV carried on an empty stomach, at least half an hour before breakfast. As a rule, one tablet (600 mg of active ingredient) is consumed per day.

Instruction for Thioctacid 600 T

Enter intravenously very slowly, not more than 50 mg of the drug in 60 seconds.
The initial daily dose is 600 mg, after a month the dosage can be reduced by half.
Do not allow the ampoules to stay in the light for a long time.

Overdose

Symptoms of overdose are convulsions, blood clotting disorders, lactic acidosis, hypoglycemic coma is possible.
It is necessary to immediately call a doctor, induce vomiting, take enterosorbents, rinse the stomach, support the life of the victim before an ambulance arrives.

Interaction

With caution combine with metal-containing drugs, cisplatinum, insulin, drugs for diabetes. It is not recommended to combine with alcohol, due to a decrease in the effectiveness of medicines.
The interval between taking iron or magnesium preparations must be at least 6-8 hours.

Storage conditions

In a dark, cool place, not above 25 degrees. Keep away from children.
Shelf life - 5 years.

Reviews about Thioctacid

Reviews for Thioctacid 600 T

Thioctacid - a preparation necessary for reception to people, suffering heavy infringements of a metabolism. Reviews about it are ambiguous, the tool, of course, helps, but often there are side effects in the form of urticaria, nausea, sometimes even tides and sudden changes in mood.

Reviews of Thioctacid BV

Reviews are the same as the solution for injection. The only thing that side effects are less common and less pronounced. In general, Thioctacid HR is a good tool for dealing with the symptoms of polyneuropathy in diabetes mellitus and after a prolonged intake of alcohol.