LoraHEXAL tabs 10mg #10

User manual for LoraHEXAL

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Composition

In 1 tablet of loratadine 1g.
Lactose monohydrate, silicon dioxide, starch, magnesium stearate as auxiliary substances.

Form of issue

Tablets, syrup, suspension.

pharmachologic effect

Anti-allergic.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The H1-histamine receptor blocker, which has a long-term effect. Suppresses the release of histamine, as well as slowly reacting substance and anaphylaxis - leukotriene C4. Prevents the appearance and alleviates the course of allergic diseases. Has antipruritic, anti-allergic, anti-edematous effect.
It causes a decrease in the permeability of capillaries, reduces the edema of tissues, and in spastic conditions it eliminates muscular spasms. The effect of the drug manifests itself after 30 minutes and lasts a day.

Pharmacokinetics

Quickly absorbed in the digestive tract and its absorption does not depend on the time of ingestion. The maximum concentration is achieved after 1.5 - 2.5 hours. 97% is associated with blood proteins.
Metabolised in the liver. The equilibrium concentration of the drug in the blood is established on the 5th day. The elimination half-life is 8.4 hours, in elderly patients it is 18.3 hours. It is excreted through the digestive tract and kidneys.

Indications for LauraGex

What can I use an antihistamine drug LoraHEXAL? It eliminates sneezing, itching of the nasal mucosa, copious discharge from the nose, burning sensation in the eyes and lacrimation, itchy skin. Appointed when:
    Pollinosis;
    urticaria;
    allergic rhinitis and conjunctivitis;
    Quincke's edema;
    itching dermatoses.
Indications for the use of LoraGEXALA also include its use in reactions to insect bites.

Contraindications

    lactation;
    pregnancy;
    intolerance and hypersensitivity to the drug;
    age up to 2 years;
    lactose intolerance, impaired absorption of glucose-galactose.
Patients with impaired liver function should be administered with caution and in a dose of not more than 5 mg. When the drug is administered, it is necessary to exclude driving.

Side effects

    anaphylactic and allergic reactions;
    headache, nervous excitability drowsiness, sometimes insomnia;
    tachycardia, arrhythmia;
    increased appetite, dry mouth, nausea;
    abnormal liver function;
    sedation in children.

Instructions for use LauraGex (Method and dosage)

Accepted inside.
Adults and children from 12 years -10 mg once a day. Children from 3 to 12 years - 5 mg once a day. With a body weight of more than 30 kg prescribe 10 mg once a day. If there is no positive dynamics of the disease within 3 days, one should think about the ineffectiveness of the drug.
Instructions for use LauraHEXALA contains a warning that patients with severe hepatic insufficiency daily dose should be reduced: adults 10 mg every other day, children weighing less than 30 kg prescribed 5 mg every other day. Correction of the dose is carried out and patients with severe renal failure - 5 mg every day or 10 mg every other day.

Overdose

It shows symptoms: drowsiness, palpitation, headache.
Treatment: there is no antidote, gastric lavage is carried out, sorbents are appointed.

Interaction

LoraHEXAL interacts with cimetidine, ketoconazole, Itraconazole, Erythromycin, Quinidine, Fluoxetine, which increase its concentration in the blood.
Phenytoin, Flumecinol, Rifampicin, barbiturates, tricyclic antidepressants reduce its effectiveness.

Terms of sale

You can buy LoraHEXAL without prescription.

Storage conditions

At a temperature not higher than 250C.
Shelf life - 3 years.

Reviews about LoraHEXAL

Reviews about LoraHEXAL are twofold: some drugs help after two days of admission, some do not notice the effect and with a longer reception. Everything depends on the course of the disease, the severity of the symptoms and individual sensitivity. Of the adverse reactions noted drowsiness, apathy, dry mouth.
According to the doctors' reviews, the drug has a multidirectional antiallergic activity and has experience with various allergic conditions. It is highly effective in allergic rhinitis, reduces bronchospasm, suppresses bronchial obstruction in bronchial asthma, and with urticaria, atopic dermatitis effectively eliminates itching, reduces the severity of rashes.