Nixar tabs 20mg #10

Nixar instruction for use

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Antihistamines are well-deservedly popular among potential consumers. These medications are in every home, as an allergy in our days is not a rare phenomenon. Nixar is a new generation drug of the Berlin-Chemie pharmacological company. We propose to learn more about it.

Composition, form of production and price

The active substance Nixar - bilastin in a dosage of 20 mg, auxiliary - microcellulose, sodium starch and magnesium stearate.
The drug has a single form of release - tablets. It belongs to the group of antihistamines of systemic action. The cost of Nixar in Russian pharmacies is 240 rubles per package, consisting of 10 tablets, in Ukrainian - 110 hryvnia for a similar form of release.

pharmachologic effect

Bilastin is an active substance of the prolonged effect, which does not cause a sedative reaction of the body. It binds to H1-receptors, causing the necessary therapeutic result.
Studies have shown that with a single intake of Nixar during the day, bilastin suppresses skin allergic reactions accompanied by eruptions like erythema and blisters filled with liquid contents. In this case, the drug facilitates the patient's well-being, softening the clinical manifestations of rhinoconjunctivitis, namely, itching and nasal discharge, reddening and lacrimation of the eyes. Practically 100% of patients noted a significant improvement in the condition.
When the control group of patients received Nixar in the recommended clinical dosage of 20 mg per day, there were no cardiovascular and psychomotor abnormalities. The effectiveness and safety of bilastin, according to the observations of a specialist, manifested itself equally in people over 60 years of age, and at a younger age.

Indications

Nixar is assigned under the following conditions:
    rhinoconjunctivitis seasonal and year-round;
    hives.

Instructions for use

The drug is used strictly by mouth. The tablet is taken orally 60 minutes before meals or 2 hours after eating.
ADULTS AND CHILDREN OF 12 YEARS
20 mg (1 tablet) once a day.
PATIENTS OVER 65 YEARS OLD
The dosage of the drug remains the same, correction is not required. The practical experience of using Nixar in the elderly is negligible.
CHILDREN UNDER 12 YEARS
The safety and therapeutic effect of the medication in this age group have not been studied, so the manufacturer does not provide recommendations for allergy therapy.
PERSONS AFFECTING KIDNEY DISEASES
Patients who have a malfunction of the urinary system, can take the drug in the recommended standard dosage - 20 mg per day without special correction.
PATIENTS WITH LIVER PATHOLOGY
Clinical studies on this group have not been conducted. But since bilastin is not metabolized in the body and is mainly excreted from it through the kidneys, systemic disorders from the liver should not arise or they will be insignificant. Therefore, such patients can take the drug according to the standard scheme.
The duration of the treatment course on an individual basis is determined by a specialist.
Patients who suffer allergic rhinoconjunctivitis, during the exacerbation of the disease and during therapy, it is important to avoid contact with potential irritants.

Side effects

Clinical studies conducted with respect to Nixar have shown that the drug rarely causes a systemic type of negative reaction from the body. But this statement is valid with strict adherence to the therapeutic regimen recommended by the manufacturer.
However, there are cases that are called otherwise than as an exception to the general rule. If a person has an individual intolerance of the active ingredient - bilastin or additional components of the drug, it is possible to develop an allergic reaction to Nixar, despite its antihistamine character. As a result, the patient complains of puffiness and itching, lacrimation, skin problems. Less common are symptoms of intolerance, such as dryness in the nose, abdominal pain, digestive disorders, tinnitus, pre-stupor and sleeplessness.
If an overdose of the drug is allowed or if it is used uncontrolled for a long time, there may be an exacerbation of cardiovascular and renal pathologies, impaired functions on the part of the liver.
Any unwanted reactions that occur in response to Nixar should be discussed with your doctor. In difficult situations, symptomatic therapy based on the appointment of adsorbents and diuretics is required, but most often all pathological phenomena disappear on their own after the drug is discontinued.

Contraindications

Nixar is not recommended for persons under the following conditions:
    increased sensitivity of the organism to the components of the drug - bilastin and auxiliary ingredients;
    children under 12 years;
    pregnancy and breastfeeding.
Safety and therapeutic efficacy of the drug is not confirmed in childhood, as clinical trials in this group of patients by the manufacturer Nixar was not carried out. For this reason, the medication is not recommended in the younger age group.
Results on the use of bilastin among pregnant women are not enough or they are not available at all, so the drug is also not used among expectant mothers.
There is no exact data on whether the active ingredient of Nixar penetrates into breast milk from specialists. In animals, this fact was not studied.
The decision to treat a drug with or without lactation depends on the physician's point of view, which will weigh all aspects in favor of breastfeeding for the baby and the need for the mother's therapy with bilastin.

Drug Interactions

It is proved that Nixar reacts with the following substances listed in the table, which improve or, on the contrary, inhibit its therapeutic effect.
FOOD PRODUCTS
Decrease the bioavailability, that is, the assimilation of bilastin, by 30%. Therefore, the drug is recommended to take at least 60 minutes before meals or 2 hours after it.
GRAPEFRUITE AND OTHER JUICES
Reduce the concentration of the active substance Nixar by at least 20%, reducing its therapeutic effect on the body. During the treatment, drinks from fresh fruit are not recommended.
ERITHROMYCIN, KETOKONAZOL, CYCLOSPORIN
When reacting with these drugs, the effectiveness of bilastin increases by a factor of 2.
DIALECTRES
The therapeutic effect of Nixar is increased by 50%.
ALCOHOLIC BEVERAGES
Simultaneous use of ethanol and bilastin at the recommended dose does not affect the psychomotor reactions of the body.

Advantages

It was said above that Nixar is a medicine of a new generation. This fact should distinguish it from medication predecessors. Let's consider, what advantages are allocated antihistamine in practice.
    Bilastin does not have a sedative effect. This means that a person taking it for a therapeutic purpose does not face psychomotor disorders and can still live fully, without giving up driving, to continue working and not to have problems with the state of health associated with drowsiness, apathy, depressive syndrome.
    Entering the body, the drug begins to act almost immediately - the improvement of the condition develops quite quickly within 60 minutes.
    The therapeutic effect of Nixar is preserved in full within the next 24 hours, which means the need for oral medication once a day.
    The drug has a high level of safety, proven clinical studies. The number of unwanted reactions of a systemic nature on the part of the body is comparable to the use of a placebo as a therapeutic agent.
    Bilastin is not metabolized in the liver tissues. It is excreted unchanged mainly through the kidneys. This aspect has been studied and allows the use of a medicament for therapeutic purposes for patients over 65 years old, as well as for persons suffering from chronic liver and urinary tract diseases.
    The drug does not interact with alcoholic beverages, which allows you to consume them in moderation during the course of treatment.
Nixar refers to medicines that are recommended by the European Academy of Allergy and Clinical Immunology.

Opinion of specialists about Nixar

Most of them believe that the abstract to the use of the drug is not provided to the potential consumer in full. After all, except for the use of medicament in the period of aggravation of allergic reactions, Nixar can be prescribed and with other health problems.
For example, doctors insist that this antihistamine is successfully used in the fight against rhinitis, sinusitis, otitis, bronchitis and other infectious and inflammatory diseases of the respiratory tract in conjunction with other medicines. In addition to them, antibacterial, antiviral, antiseptic and immunomodulating medications must be prescribed.
In all these cases and other pathologies of the respiratory system, hearing, Nixar's reception allows to completely eliminate the swelling of the mucous membranes. With genyantritis and otitis medication improves respiratory function, facilitating the rapid absorption of other medicinal components. The pathological processes that arise in the ear-throat-nose system are also eliminated with bilastin, which positively affects the general condition of the patient. According to the experts themselves, in the case of respiratory tract diseases, Nixar becomes an excellent alternative option for preparations based on xylometazoline, phenylephrine and naphazoline.
Doctors believe that he should be in the home medicine chest of every person who suffers from allergic diseases. In emergency situations, the agent can be taken once to stop the clinical manifestations of the pathological process. But you should not rely on self-medication, any negative reaction of the body should be regarded by a doctor.
in the field of allergy experts warn about a particular Niksar - simultaneous reception of the drug with food and fruit juice reduces its uptake by almost half, at least 30%.
Undoubtedly, this fact affects the therapeutic effect of the drug, so it is important not to combine its oral use with a meal or these drinks.
In addition, Nixar is, perhaps, the only antihistamine drug that is compatible with alcohol. It does not interact with ethyl alcohol, and therefore has no effect on the patient's CNS. Therefore, this medication can be combined with the use of hot drinks, of course, in modest limits. This information can be useful to people whose work is directly related to alcohol, for example, it is a question of tasters of different wines.
Also, experts remind that Nixar, like any medication, is able to interact with outside medications. For example, simultaneous use with Erythromycin enhances the effectiveness of bilastin.
That is why any appointment of Nixar is considered by a doctor individually, and self-medication should not be carried out in principle.
Doctors say that the risk located in the middle of the pill does not mean that the drug can be divided into several receptions. It is provided by the manufacturer to facilitate swallowing of the medicine, if it becomes necessary to partially grind it. Therefore, it is impossible to offer Nixar to children under 12 years of age, with the hope of artificially reducing the dosage of the drug.

Reviews

The drug has mostly positive feedback. Most specialists and their patients remain satisfied with the antihistamine therapy.
Consumers believe that the instruction to the drug is too complex and this is perhaps the only negative of the drug, provided it is well tolerated. They also note that no long-term adverse effects of a systemic nature have occurred on the part of the body if the treatment was carried out strictly according to the recommended scheme.
Also, all patients emphasize the convenience of taking Nixar. And it's not surprising - just one tablet a day and you can forget about allergies until the next day. But many analogues of this antihistamine mean more frequent oral medication, which can not always be convenient for the patient.
In addition, many patients argue that Nixar does not provoke the development of drowsiness, fatigue and other negative effects on the part of the nervous system, which can not be said about other antiallergic drugs. The drug can be taken even shortly before a night's sleep and in the morning, hardly waking up, a person will not suffer from fatigue and allergies.
Patients who used Nixar for respiratory tract infections believe that, in combination with other medications, it contributes to the rapid recovery and elimination of severe edema caused by nasal congestion.
Experts advise using this drug as a substitute for standard nasal drugs, produced as a spray and droplets based on xylometazoline and phenylephrine.
This technique is quite relevant when long-term treatment of respiratory tract pathologies is necessary, and the use of these vasoconstrictors is acceptable for a strictly limited time. For example, drops with xylometazoline can not be used for longer than one week in adult patients and 5 days in children and the elderly. But in fact often the duration of the disease takes much longer.
In conclusion, I want to add that Nixar is an antihistamine highly effective means of prolonged action. It is very convenient to use, the price for it is available in pharmacies in Russia and Ukraine. The only thing that I want to recall is that the appearance of allergic reactions of any type should not be the reason for self-medication. Only a qualified specialist can choose the right therapy regimen, which contributes to an early recovery and excludes the risk of side effects.