Zyrtec 10mg #20
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Zyrtec instruction for useYou can buy Zyrtec onlineZyrtec tablets belong to the pharmacological group of medicines antihistamines. They are used for pathogenetic therapy (treatment aimed at the mechanism of development of the path..
Zyrtec instruction for use
You can buy Zyrtec online
Zyrtec tablets belong to the pharmacological group of medicines antihistamines. They are used for pathogenetic therapy (treatment aimed at the mechanism of development of the pathological process) of allergic reactions.
Form of issue and composition
Zyrtec tablets have an oblong shape, biconvex surface, in the middle, on the one hand, there is a dividing risk. The tablets are coated with an enteric film membrane film. The main active substance of the drug is cetirizine, its content in 1 tablet is 10 mg. It also contains auxiliary connections, which include:
Silica colloidal anhydrous.
Zyrtec tablets are packaged in a blister pack of 7 and 10 pieces. Cardboard pack contains 1 or 2 blisters and instruction on the use of the drug.
The active substance tablets Zyrtec cetirizine belongs to the group of compounds - antihistamines. It blocks specific H1-receptors of cells, which react to the action of the mediator compounds of the allergic reaction, in particular histamine. Therefore, with an increase in the level of histamine in the body due to the development of an allergic reaction, cetirizine has an antihistamine pharmacological effect, which consists of such therapeutic effects:
Decrease in the severity of itching, caused by direct irritation of histamine sensitive endings.
Reduction of edema of soft tissues - blocking of receptors to histamine decrease in the permeability of the vascular wall and the release of plasma into the intercellular substance.
Reduction of spasm of smooth muscles of hollow organs is a pronounced increase in the tone of muscle fibers caused by histamine.
Reduction of skin eruptions, which are the result of a specific inflammatory reaction that develops as a result of migration of cells of the immune system (neutrophils, eosinophils).
Also, cetirizine stabilizes the cytoplasmic membrane of mast cells (tissue immune cells, which in the development of an allergic reaction synthesize histamine), thereby reducing the level of histamine and other mediators of an inflammatory allergic reaction. The active substance of Zyrtec tablets does not cause a sedative (sedative) and hypnotic effect.
After taking Zyrtec tablets inside, cetirizine is quickly and completely absorbed from the upper parts of the digestive tract into the blood. It is evenly distributed in the tissues of the body with subsequent metabolism in the cells of the body to inactive decay products. They are mostly excreted from the body with urine by the kidneys. The half-life (half the entire dose of the drug) is about 10 hours.
Indications for use
The main indication for taking Zyrtec tablets is the development of various clinical forms of allergy, which include:
Allergic rhinitis is an inflammation of the nasal mucosa, which is seasonal in nature (it is often provoked by pollen from plants, during their active flowering).
Allergic conjunctivitis is an inflammatory reaction of the conjunctiva of the eyes.
Hay fever (pollinosis) is a systemic allergic reaction to plant pollen.
Urticaria is a characteristic rash on the background of a slight swelling of the skin, which looks like a nettle burn.
Allergic dermatosis, including atopic dermatitis, is a local reaction accompanied by the development of a rash on the skin and its itching.
Zyrtec tablets can also be used as part of the complex treatment of severe allergic reactions (atopic bronchitis, angioedema Quincke).
Contraindications for use
Absolute contraindications to the reception of Zyrtec tablets are such pathological and physiological states of the body:
Individual intolerance to cetirizine or any of the excipients of the drug.
Severe form of kidney failure.
Pregnancy at any time of its course.
Lactation period (breastfeeding).
Children under 6 years.
Lactose intolerance (lactase deficiency, glucose-galactose malabsorption), accompanied by a breakdown in the digestion or absorption of carbohydrate in the gastrointestinal tract.
With caution, Zyrtec tablets are used for renal failure of moderate severity, in the elderly, in persons with concomitant epilepsy (central nervous system damage, which is accompanied by periodic seizures). Before starting the drug it is important to make sure that there are no contraindications to its use.
Dosing and Administration
Zyrtec tablets are taken orally. They are taken whole, not chewed and washed down for better passage through the esophagus with enough water. The initial dose of the drug is 5 mg (1/2 tablet). In the future, if necessary, it is possible to increase it to 10 mg (1 tablet). Reception mode - once a day. The course of treatment is individual, it is determined by the disappearance of clinical symptoms of an allergic reaction.
The use of Zyrtec tablets may be accompanied by the development of unwanted reactions from various organs and systems, which include:
The digestive system - dry mouth, nausea, less likely diarrhea (diarrhea) and pain in the abdomen.
Cardiovascular system - tachycardia (more frequent heartbeats over the norm).
Nervous system - headache, dizziness, fatigue, the appearance of drowsiness, less often develops paresthesia (a violation of skin sensitivity), loss of consciousness in the form of fainting, tremor (trembling) of the hands, a nervous tic of different localization, often affects mimic muscles.
Higher nervous activity is arousal, aggressive behavior is rare enough, a pronounced and prolonged depression of mood (depression), suicidal ideation, hallucinations and sleep disturbance.
The sense organs are a spasm of accommodation, an unclear vision of objects, a vertigo (a violation of the functional activity of the inner ear with the development of pronounced dizziness).
Skin and subcutaneous tissue - the appearance of a rash, less often the development of urticaria or angioedema.
Allergic reactions - very rarely observed the development of anaphylactic shock (severe systemic allergic reaction with pronounced decrease in blood pressure and multiple organ failure).
Laboratory indicators - increased activity in the blood of enzymes of liver transaminases (ALT, AST).
General changes - rarely there is an increase in appetite and body weight, a general malaise (asthenia).
Depending on the type and severity of side effects, the dose of the drug is reduced or canceled.
Before starting Zyrtec tablets, it is important to read the instructions for the drug carefully and pay attention to such specific instructions:
Cetirizine promotes retention of urine with certain concomitant diseases - benign prostatic hyperplasia (adenoma), spinal cord injuries, affecting the functional activity of the pelvic organs.
Excluded is the intake of alcohol during the use of the drug, since Zyrtec tablets enhance its activity against the structures of the central nervous system.
The drug has no direct effect on higher nervous activity, nevertheless, in view of the potential risk of developing a sedative effect, it is worthwhile to refrain from activities requiring increased concentration of attention and speed of psychomotor reactions.
Pharmacies release Zyrtec tablets without a prescription. The appearance of questions or doubts about their admission is the basis for consultation with a doctor.
In the case of a significant excess of the recommended therapeutic dose of Zyrtec tablets (a single dose of more than 50 mg), the overdose symptom develops, which includes confusion, mydriasis (dilated pupils), dizziness, headache, hand tremors, urinary retention, general weakness, skin itching. Treatment consists in washing the stomach, intestines, and taking intestinal sorbents (activated charcoal). Symptomatic and supportive therapy is also used. There is no specific antidote for today, hemodialysis (hardware purification of blood) does not reduce the level of cetirizine in the blood.
Analogues of Zyrtec tablets
Terms and conditions of storage
The shelf life of Zyrtec tablets is 5 years from the date of their manufacture. Keep the drug in a dry place inaccessible to children at an air temperature of not more than + 30 ° C.