Oestrogel gel 0.06% 80gr

Oestrogel – Estradiol Gel for Menopausal Symptom Relief

Buy Oestrogel here – effective estradiol gel for external estrogen replacement therapy.

Composition

Each gram of gel contains 600 μg estradiol, the active hormone ingredient.

Other components include carbomer, ethanol, trolamine, and purified water.

Form & Packaging

Oestrogel is available as an 80-gram tube with a dispenser. One dose is 2.5 grams of gel, delivering 1.5 mg of estradiol.

Pharmacologic Effect

Oestrogel provides hormonal estrogen replacement for women, effectively reducing menopausal symptoms such as hot flashes, mood swings, vaginal dryness, and preventing bone density loss.

How It Works (Pharmacodynamics & Pharmacokinetics)

• Topical estradiol penetrates the skin quickly, entering systemic circulation without first-pass liver metabolism.
• Peak plasma estradiol levels occur 3–4 hours post-application.
• Helps lower total cholesterol and supports balanced blood coagulation factors.
• Estradiol metabolism resembles natural estrogen processing in the body.

Indications for Use

• Relief of menopausal and climacteric symptoms (natural or induced)
• Prevention and treatment of postmenopausal osteoporosis

Contraindications

• Ischemic or hemorrhagic stroke
• Pregnancy and breastfeeding
• Acute thromboembolism or thrombophlebitis
• Liver diseases and syndromes such as Rotor or Dubin-Johnson
• Estrogen-dependent tumors or suspected malignancies
• Hypersensitivity to ingredients

Precautions

Use with caution in conditions such as diabetes, liver dysfunction, hypertension, migraine, endometriosis, gallbladder disease, and history of thrombosis. Regular gynecological check-ups are recommended during long-term use.

Possible Side Effects

• Local skin irritation or redness
• Headache, dizziness, mood changes
• Breast tenderness or enlargement
• Menstrual irregularities (bleeding, spotting)
• Digestive symptoms such as nausea, gallbladder issues (rare)
• Allergic reactions, edema, weight changes

How to Use Oestrogel

Apply once daily on clean, dry skin of the abdomen, forearms, shoulders, or lower back. Use one dose (2.5 g) and allow it to absorb completely (2–3 minutes). Avoid applying to mucous membranes or breast skin.

Application should cover an area approximately the size of both palms. Sticky residue after 5 minutes indicates insufficient application area.

Overdose

Excessive use may cause nausea, vomiting, or uterine bleeding. Discontinue use and seek medical advice if symptoms occur.

Drug Interactions

• May reduce effectiveness of antihypertensives, anticoagulants, and hypoglycemic drugs
• Increased effect of lipid-lowering agents
• Drugs inducing liver enzymes (e.g., Rifampicin, Carbamazepine) reduce estradiol levels
• Reduced effectiveness of diuretics and male hormones
• Opioids and tranquilizers may accelerate estradiol metabolism

Storage

Store at temperatures up to 25°C, protect from light. Shelf life: 3 years.

Special Instructions

• Before starting therapy, undergo a full gynecological exam.
• Consider combined treatment with progesterone to protect the endometrium.
• Do not use as contraception.
• Discontinue prior to surgery (4–6 weeks before).
• Monitor blood pressure, liver function, and glucose levels during treatment.
• Avoid contact with mucous membranes and breasts during application.
• Discontinue if serious adverse symptoms (thrombosis, jaundice, migraine, high blood pressure) occur.

Use in Children and Pregnancy

Not recommended for children, pregnancy, or breastfeeding.

User Reviews

Many women report effective relief of menopausal symptoms with Oestrogel, highlighting its convenient dosing, quick absorption, and minimal residue compared to oral estrogens.

Order Oestrogel now for effective and gentle hormone replacement therapy.