Cholithylin caps 400mg #14

Cholithylin user manual

You can buy Cholithylin here

Composition

1 ml. solution for intravenous and intramuscular administration contains:
active ingredient: choline alfoscerate polyhydrate (Lipoid GPC-85F) 250 mg;
excipients: povidone, water for injections;
1 capsule contains:
active ingredient: choline alfoscerate hydrate (glyceryl phosphorylcholine hydrate), in terms of choline alphoscerate (L-a-glycerophosphorylcholine) 400 mg;
excipients: purified water, macrogol (polyethylene glycol 400), povidone (plasdone C-15 or kollidon 17 PF);
soft gelatin capsule composition: gelatin, glycerol (glycerin), methylparaben (methylparahydroxybenzoate), propylparaben (propylparahydroxybenzoate), sorbitol (sorbitol), titanium dioxide, iron dye yellow oxide, iron dye red oxide, black dye black oxide, purified water

pharmachologic effect

Cholithylin is a nootropic agent. Central holostimulyator, which contains 40.5% of metabolically protected choline.
Provides synthesis of acetylcholine and phosphatidylcholine in neuronal membranes, improves blood flow and enhances metabolic processes in the central nervous system, activates the reticular formation. Increases the linear speed of blood flow, contributes to the normalization of the spatial and temporal characteristics of spontaneous bioelectric activity of the brain, regression of focal neurological symptoms and recovery of consciousness; It has a positive effect on the cognitive and behavioral reactions of patients with vascular diseases of the brain (dyscirculatory encephalopathy and residual cerebrovascular events).
It has a preventive and corrective effect on the pathogenetic factors of involutional psychoorganic syndrome, reduces cholinergic activity. Stimulates the dose-dependent release of acetylcholine under physiological conditions; participating in the synthesis of phosphatidylcholine (membrane phospholipid), improves synaptic transmission, the plasticity of neuronal membranes. Does not affect the reproductive cycle and does not have a teratogenic, mutagenic effect.

Pharmacokinetics

Solution: Choline Alphoscerate easily penetrates the blood-brain barrier. Excreted mainly by the lungs in the form of carbon dioxide (85%), as well as the kidneys and through the intestines (15%).
Capsules Cholithylin: Absorption - 88%. It easily penetrates the blood-brain barrier (when taken orally, the concentration in the brain is 45% of that in plasma). Excreted mainly by the lungs, in the form of carbon dioxide (85%), as well as by the kidneys and through the intestines (15%).

Cholithylin, indications for use

In complex therapy for:
    traumatic brain injury with a predominantly stem lesion level (acute period);
    cerebrovascular insufficiency;
    psychoorganic syndrome on the background of degenerative diseases and involutionary processes of the brain;
    multi-infarction dementia.

Contraindications

    hypersensitivity;
    hemorrhagic stroke (acute stage);
    pregnancy;
    breastfeeding period;
    age up to 18 years.

Dosage and administration

Cholithylin is administered intramuscularly at a dose of 1 g (1 ampoule) per day or intravenously slowly at 1 g per day for 15–20 days. In the future, it is possible to switch to the oral form of Cholithylin (capsule).
Inside, 0.4 g 3 times a day for 3-6 months.
In the subacute period of traumatic brain injury, 0.8 g in the morning and 0.4 g in the afternoon for 6 months.

Side effects

On the part of the digestive system: constipation, diarrhea, dryness of the oral mucosa, pharyngitis.
From the nervous system: headache, drowsiness, insomnia, aggressiveness, anxiety, nervousness, dizziness.
For the skin: rash, urticaria.
Other: pain at the injection site, increased urination.

special instructions

During the period of treatment, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and psychomotor speed.

Interaction

Drug interaction of Cholithylin is not installed.

Indications for use

Traumatic brain injury

Storage conditions

Shelf life - 2 years.
In a dry, dark place at a temperature not higher than 25 ° C.

Terms of sell

You can buy Cholithylin without a prescription.