Pantogam syrup 10% 100ml

Pantogam syrup instruction

You can buy Pantogam syrup on this page

Composition

active ingredient: calcium hopantenate (Pantogam®) - 10.0 g;
excipients: glycerol (in terms of 100%) 25.8 g, sorbitol 15.0 g, citric acid monohydrate 0.1 g, sodium benzoate 0.1 g, aspartame 0.05 g, food flavoring “Cherry 667” 0 , 01 g, purified water - up to 100 ml.

Description

Colorless or slightly yellowish liquid with a cherry smell
Pharmacotherapeutic group - nootropic agent
ATC-N06BX Code

Pharmacological properties

Pharmacodynamics

The spectrum of action of pantogam syrup is associated with the presence of gamma-aminobutyric acid in its structure. The mechanism of action is due to the direct influence of pantogam syrup on the GABCR - receptor-channel complex. Pantogam syrup has a nootropic and anticonvulsant action. Pantogam increases brain resistance to hypoxia and the effects of toxic substances, stimulates anabolic processes in neurons, combines a moderate sedative effect with a mild stimulating effect, reduces motor excitability, and activates mental and physical performance. Improves GABA metabolism in chronic alcohol intoxication and after the abolition of ethanol. Able to inhibit acetylation reactions involved in the inactivation mechanisms of novocaine and sulfonamides, which results in a prolonged action of the latter. It causes inhibition of the pathologically increased gallbladder reflex and detrusor tone.

Pharmacokinetics

Pantogam syrup is rapidly absorbed from the gastrointestinal tract, penetrates the blood-brain barrier, the highest concentrations are created in the liver, kidneys, in the wall of the stomach and skin. Pantogam syrup is not metabolized and excreted unchanged within 48 hours: 67.5% of the dose taken is excreted by the kidneys, 28.5% is excreted in the feces.

Indications for use

children with perinatal encephalopathy from the first days of life;
various forms of cerebral palsy;
mental retardation of varying severity, including behavioral disorders;
violations of the psychological status of children in the form of a general delay in mental development, specific speech disorders, motor functions and their combination, the development of school skills (reading, writing, counting, etc.);
hyperkinetic disorders, including attention deficit hyperactivity syndrome;
neurosis-like states (with stuttering, predominantly clonic form, tics, inorganic encopresis and enuresis);
decrease in mnostico-intellectual productivity due to arteriosclerotic changes of cerebral vessels, with initial forms of senile dementia, organic lesions of the brain of traumatic, toxic, neuroinfectious genesis;
schizophrenia with cerebral organic deficiency (in combination with psychotropic drugs);
extrapyramidal disorders in organic brain diseases (myoclonus epilepsy, Huntington's chorea, hepatolentic degeneration, Parkinson's disease, etc.), as well as for the treatment and prevention of extrapyramidal syndrome caused by the administration of neuroleptics;
epilepsy with delayed mental processes and reduced cognitive productivity in conjunction with anticonvulsants;
psycho-emotional overload, reduced mental and physical performance, to improve concentration and memorization;
neurogenic urination disorders (pollakiuria, urgency, imperative urinary incontinence).

Contraindications

Hypersensitivity to Pantogam syrup, acute severe kidney disease, pregnancy (1 trimester), phenylketonuria (syrup contains aspartame).

Dosage and administration

Pantogam syrup 100 mg / ml is taken orally 15-30 minutes after eating. A single dose for adults is usually 2.5 - 10 ml (0.25 - 1 g), for children - 2.5 - 5 ml (0.25 - 0.5 g); the daily dose for adults is 15–30 ml (1.5–3 g), for children — 7.5– 30 ml (0.75–3 g). The course of treatment is 1 - 4 months, sometimes up to 6 months. After 3 - 6 months, it is possible to repeat the course of treatment.
Depending on the age and pathology of the nervous system, the following dose range is recommended for children: children of the first year - 5 - 10 ml (0.5 - 1 g) per day, up to 3 years - 5 - 12.5 ml (0.5 - 1.25 g) per day, for children from 3 to 7 years old - 7.5-15 ml (0.75 - 1.5 g), older than 7 years old - 10 - 20 ml (1 - 2 g). Treatment tactics include increasing the dose within 7 to 12 days, taking the maximum dose for 15 to 40 days or more, with a gradual decrease in dose to cancellation within 7 to 8 days. The course of treatment is 30 - 90 days (for certain diseases up to 6 months or more).
With schizophrenia in combination with psychotropic drugs - from 5 to 30 ml (0.5 - 3 g) per day. The course of therapy is from 1 to 3 months. With epilepsy in combination with anticonvulsants - in a dose of 7.5 to 10 ml (0.75 - 1 g) per day. The course of therapy is up to 1 year or more. In neuroleptic syndrome, accompanied by extrapyramidal disorders, the daily dose is up to 30 ml (up to 3 g), treatment for several months. When extrapyramidal hyperkinesis in patients with organic diseases of the nervous system - from 5 to 30 ml (0.5 - 3 g) per day. The course of treatment is up to 4 months or more.
With the consequences of neuroinfections and head injuries - from 5 to 30 ml (0.5 - 3 g) per day.
To restore performance at elevated loads and asthenic conditions, 2.5-5 ml (0.25-0.5 g) 3 times a day are prescribed to pantogs.
In children with urination disorders, 2.5 to 5 ml each (0.25 to 0.5 g), the daily dose is 25 to 50 mg / kg, the course of treatment is 1 to 3 months; adults, 5 to 10 ml (0.5 to 1 g), 2 to 3 times a day.
In conditions of long-term treatment, simultaneous administration of Pantogam syrup with other nootropic and stimulating agents is not recommended. Taking into account the nootropic effect of the drug, its administration is preferably carried out in the morning and afternoon hours.

Side effect

Allergic reactions are possible (rhinitis, conjunctivitis, skin allergic reactions). In this case, cancel Pantogam syrup. Very rarely observed adverse reactions from the central nervous system (hyper-arousal, sleep disturbance or drowsiness, lethargy, lethargy, headache, dizziness, noise in the head). In this case, reduce the dose of the drug.

Overdose

Strengthening the symptoms of side effects (sleep disturbances or drowsiness, noise in the head). Treatment: activated carbon, gastric lavage, symptomatic therapy.

Interaction Pantogam syrup with other drugs

Prolongs the action of barbiturates, enhances the action of anticonvulsants, prevents the side effects of phenobarbital, carbamazepine, neuroleptics. The effect of pantogam syrup is enhanced in combination with glycine, etidronic acid. Potentiates the action of local anesthetics (procaine).

Release form

Syrup 100 mg / ml. On 100 ml in the bottles of dark glass, corked by covers with a control ring of the first opening. Each bottle together with a measuring spoon with a nominal volume of 5 ml with a risk marked “%” (which corresponds to 2.5 ml) or with a measuring spoon with a nominal volume of 5 ml with risks marked with “%” and “%” (which corresponds to 1.25 ml and 2.5 ml), with instructions for use are placed in a pack of cardboard.

Storage conditions

Store in a dark place at a temperature not exceeding 25 ° C. After opening store in the refrigerator no more than 1 month. Keep out of the reach of children.
Shelf life - 2 years. Do not use after expiration date. strong>

Terms of sale from pharmacies.

You don't need a prescription to buy Pantogam syrup.