Pantogam activ caps 300mg #60

Pantogam activ instruction

You can buy Pantogam activ online

Composition

1 capsule contains 200 mg or 300 mg of Hepatenic acid (D, L) - the active substance.
Auxiliary ingredients according to the mass content of the active substance:
    1.02 mg or 1.53 mg of magnesium stearate;
    13.98 mg or 20.97 mg of microcrystalline cellulose.
Capsules:
    gelatin;
    titanium dioxide;
    methylparahydroxybenzoate;
    sodium lauryl sulfate;
    glycerol;
    propyl parahydroxybenzoate;
    purified water.

Form of issue

The drug Pantogam is produced in the form of capsules of 200 mg or 300 mg.
One package can contain 30, 50 or 60 capsules.

pharmachologic effect

Nootropic.

Pharmacodynamics and pharmacokinetics

Pantogam, the active, in its structure, contains gamma-aminobutyric acid (GABA), directly affecting the GABAK receptor-channel complex. The drug is a racemic mixture of equivalent fractions of Hopantenic acid in the R form and its S-isomer, which improves the transport and interaction of the drug with the GABA receptors. The Pantogam preparation has a more pronounced anticonvulsant and nootropic effect than the first-generation drugs containing Hopantenic acid.
Pantogam, an active increases the resistance of the brain to a lack of oxygen (hypoxia), as well as to the effects of substances poisoning it, activates anabolic processes in the neurons of the brain, combines a mild stimulating effect with a mild sedative effect. It shows mild anti-anxiety and anti-asthenic activity. Reduces motor excitability, activates physical and mental activity, organizes behavior. Prevents the pathological increase of the vesicle reflex, as well as the detrusor tone.
With oral intake of active substance Pantogam, the active is rapidly absorbed from the digestive tract.
Has the ability to penetrate the BBB.
It is not metabolized and for 48 hours it is excreted unchanged by the kidneys - about 70% and the intestines - about 30%, the previously taken dose.

Indications for use

    epilepsy (with concomitant use of anticonvulsants);
    cerebrovascular insufficiency, due to atherosclerotic pathologies of cerebral vessels;
    cognitive impairment in neurotic disorders, as well as caused by organic brain lesions (including the consequences of craniocerebral trauma and neuroinfections);
    extrapyramidal hyperkinesis (Parkinson's disease, Huntington's chorea, myoclonus-epilepsy, hepatolenticular degeneration, etc.), therapy of extrapyramidal syndrome, which was caused by the use of neuroleptics;
    reduction of physical and mental activity, psycho-emotional overload, with the aim of improving memory and concentration of attention;
    schizophrenia (used as part of complex treatment);
    neurogenic disorders of urination (enuresis, pollakiuria, imperative urinary retention, imperative urge to urinate).

Contraindications

    hypersensitivity to Hepatenic acid or other capsule ingredients;
    severe or acute kidney pathology;
    period of breastfeeding;
    the first trimester of pregnancy;
    the patient's age is up to 18 years (due to the lack of clinical studies on the impact of Pantogam's asset at an earlier age).

Side effects

In some cases, allergic reactions (rashes on the skin, conjunctivitis, rhinitis) were observed. In case of manifestation of these symptoms, a dose reduction or complete withdrawal of therapy is recommended.
Also, short-term passing symptoms were noted: noise in the head, sleep disturbance or drowsiness.

Instructions for use Pantogam asset (Method and dosage)

Medication Pantogam is an active for oral (internal) reception. As a rule, the drug is taken 15-20 minutes after eating, 2 or 3 times a day. Recommended time of reception in the morning or afternoon.
The usual dosage regimen of 200 mg capsules is 0.2-0.8 g (1-4 capsules) per day.
A capsule of 300 mg - 0.3-0.9 g (1-3 capsules) per day.
The maximum allowable daily dose of Pantogam's active is 2.4 g (12 capsules of 200 mg or 8 capsules of 300 mg).
The course of therapy lasts from 30 days to 4 months, in some cases, treatment is continued for 6-12 months. After 3-6 months, a repeat course of therapy can be performed.

Overdose

In case of an overdose of Pantogam, the active may increase the symptoms of its side effects.
It shows gastric lavage, reception of enterosorbents, symptomatic therapy.

Interaction

Pantogam activates the effect of anticonvulsant drugs.
Potentiates the effects of drugs used for local anesthesia (Procaine).
When combined with barbiturates prolong their action.
Prevents side effects of carbamazepine, phenobarbital, neuroleptics.
The combination of Etidronic acid and Glycine increases the effect of Pantogam's active.

Storage conditions

At a temperature of no higher than 25 ° C.
Shelf life - 36 months.

special instructions

When Pantogam is used for an extended period of time, simultaneous administration of other drugs with a stimulating CNS and nootropic action is not recommended.

Children

Not assigned to patients under the age of 18, due to the lack of clinical studies on the effects of Pantogam's active at this age.

During pregnancy (and lactation)

Pantogam, the active is contraindicated for use during pregnancy (I trimester), as well as during breastfeeding.

Reviews about Pantogam active

Patients' comments on Pantogam are active in neurotic disorders, epilepsy and schizophrenia (in complex therapy), cognitive impairment due to brain trauma, cerebrovascular insufficiency, suggest high efficacy of the drug with minimal adverse events.
Excellent results show its use at psycho-emotional overloads, with the purpose of increasing mental activity and efficiency, as well as in cases of urinary disorders due to neurological diseases.
It should be remembered that the Pantogam drug is intended for adults only and is contraindicated in children under 18 years of age. Especially for the treatment of children, a synonym for Pantogam Active - Pantogam in the form of a syrup is issued.