Sialor Rino 0.05% 10ml

Sialor Rino instruction for use

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To buy Sialor Rino for babies (0.01%) or Sialor Rino for children (0.025%) just contact us

Composition per ml:

Active substance:
Oxymetazoline hydrochloride 0.5 mg
Excipients:
benzalkonium chloride 0.15 mg
disodium edetate (Trilon B) 0.5 mg
sodium hydroxide (0.1 M sodium hydroxide solution) to pH 6.0-7.0
sodium dihydrogen phosphate dihydrate (sodium phosphate monosubstituted 2-water) - 1.29 mg
sodium hydrogen phosphate dodecahydrate (sodium phosphate disubstituted 12-water) - 1.76 mg
purified water - up to 1 ml

Description

Transparent colorless or slightly colored liquid.
Pharmacotherapeutic group: anticongestive agent - alpha-adrenomimetic.
ATX Code: R01AA05

Pharmacological properties of Sialor Rino

Pharmacodynamics

Oksimetazolin belongs to the group of alpha-adrenostimulators for topical application. Has vasoconstrictive effect. With intranasal administration reduces swelling of the mucous membrane of the upper respiratory tract and discharge from the nose. Restores nasal breathing. Elimination of the edema of the mucous membrane of the nasal cavity facilitates the restoration of the aeration of the paranasal sinuses of the nasal cavity, the middle ear cavity, which reduces the likelihood of bacterial complications (sinusitis, sinusitis, otitis media). With local intranasal use in therapeutic concentrations, it does not irritate and does not cause hyperemia of the mucous membrane of the nasal cavity. Sialor Rino starts to act quickly, within a few minutes. Duration of Sialor Rino up to 12 hours.

Pharmacokinetics

With local intranasal application, oxymetazoline does not have a systemic effect. The half-life of oxymetazoline with its intranasal administration is 35 hours. 2.1% of oxymetazoline is excreted in the urine and about 1.1% with feces.

Indications for use

    treatment of acute respiratory diseases accompanied by a runny nose;
    allergic rhinitis;
    vasomotor rhinitis;
    for restoration of drainage with inflammation of the paranasal sinuses of the nasal cavity, eustachiitis, otitis media;
    for elimination of edema before diagnostic manipulations in the nasal passages.

Contraindications for Sialor Rino

    hypersensitivity to the components of Sialor Rino;
    atrophic (dry) rhinitis;
    administration of monoamine oxidase inhibitors during the previous 2 weeks and within 2 weeks after their withdrawal;
    angle-closure glaucoma;
    surgical interventions on the dura mater (in the anamnesis);
    condition after transsphenoidal hypophysectomy;

Carefully

In patients with increased intraocular pressure, suffering from diseases of the cardiovascular system (arterial hypertension, ischemic heart disease, chronic heart failure, tachycardia, arrhythmias), a violation of carbohydrate metabolism (diabetes mellitus), thyroid dysfunction (hyperthyroidism), pheochromocytoma, chronic renal disease deficiency, prostatic hyperplasia (urinary retention), severe atherosclerosis, porphyria, pregnancy, the period of breastfeeding, as well as patients receiving tricyclic antidepressants and bromocriptine.

Application Sialor Rino in pregnancy and during breastfeeding

When used during pregnancy or breastfeeding, the recommended dose should not be exceeded. The drug can be used only if the expected benefit for the mother exceeds the potential risk to the fetus and the baby. It is necessary to consult a doctor.

Dosing and Administration

Intranasally.
    Adults and children over 6 years of age: Apply 1 to 2 drops of 0.05% solution in each nasal passage 2 to 3 times a day.
It is not recommended to use Sialor Rino for more than 7 days. With frequent and prolonged use of the drug, the sensation of "congestion" of the nose may appear again or worsen. If these symptoms appear, discontinue treatment and consult a doctor.

Side effects of Sialor Rino

Burning or dryness of the mucous membranes of the nasal cavity, dryness of the mucous membranes of the mouth and throat; sneezing; increase in the amount of secretion from the nose, nosebleeds; after the effect of using Sialor Rino has passed, a strong sense of "stuffiness" of the nose (reactive hyperemia).
Side effects due to the systemic effect of the drug: increased blood pressure, headache, dizziness, palpitations, tachycardia, anxiety, anxiety, fatigue, drowsiness, sedation, irritability, sleep disorders (in children), nausea, insomnia, exanthema, eyesight, hallucinations, Quincke's edema, itching, seizures, respiratory arrest (in infants). With prolonged use - tachyphylaxis, reactive hyperemia of the mucosa and atrophy of the mucous membrane of the nasal cavity.
Preservative benzalkoniya chloride, which is part of Sialor Rino, can cause swelling of the mucous membrane of the nasal cavity. If this happens, it is necessary to change the drug to another, which does not contain preservatives.
If you experience side effects indicated in the instructions or are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

Overdose

In case of accidental ingestion or overdose, the following symptoms may appear: anxiety, anxiety, hallucinations, convulsions, lowering of body temperature, lethargy, drowsiness, coma, narrowing or dilating pupils, fever, sweating, pallor, cyanosis, palpitations, bradycardia, arrhythmia, cardiac arrest, increased blood pressure, lower blood pressure, nausea, vomiting, respiratory depression, respiratory arrest.
Treatment: symptomatic. At casual reception inside - gastric lavage, reception of the activated coal. Vasopressor drugs are contraindicated.

Interaction with other drugs

When used simultaneously with monoamine oxidase inhibitors (including the period within 14 days after their withdrawal), tricyclic antidepressants or other drugs that increase blood pressure, there may be an increase in blood pressure. Sialor Rino slows the absorption of local anesthetic drugs, lengthens their action.
Co-administration of other vasoconstrictor drugs increases the risk of side effects.
If you use the above or other medications (including OTC drugs), consult your doctor before using Sialorharino.

special instructions for Sialor Rino

In the recommended dose without consulting a doctor, use no more than 7 days. If the symptoms increase or the improvement does not occur within 3 days, you should consult your doctor. Avoid contact with eyes.
To avoid the spread of infection, it is necessary to use the drug individually. After opening, use within 14 days.
With prolonged use and overdose of oxymetazoline, the therapeutic effect may be weakened, as well as the risk of reactive hyperemia (drug rhinitis) and atrophy of the nasal mucosa.
Influence on ability to drive vehicles, mechanisms
After long-term use of colds containing oxymetazoline, in doses exceeding the recommended ones, one can not exclude the general effect on the cardiovascular system and the central nervous system. In these cases, it is advisable to use caution when driving vehicles and engaging in other potentially hazardous activities requiring increased attention and speed of psychomotor reactions.

Form of issue

Nasal drops are 0.01%, 0.025% and 0.05%.
1 ml each in a dropper with a valve (for a concentration of 0.01%) or 2 ml in a tubing with a valve (for a concentration of 0.025%) or 10 ml in a polymer vial (for a concentration of 0.05%).
On a tube-droppers, ampoules, vials glue labels.
2, 5 tubes for 1 ml (for a concentration of 0.01%) or 2, 5 tubes of 2 ml (for a concentration of 0.025%) with instructions for use are placed in a pack of cardboard.
1 ampoule of polymer for 10 ml (for a concentration of 0.05%) complete with a bottle of dark glass with a screw mouth, sealed with a nozzle-sprayer, with instruction for use put in a pack of cardboard.

Storage conditions

In the dark place at a temperature of no higher than 25 ° C.
Keep out of the reach of children.
Shelf life - 3 years. Do not use after expiry date.

Leave conditions

You can buy Sialor Rino without a prescription.