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Choludexan caps 300mg #20

  • $37.82
  • 3 or more $36.90
  • Availability:Out Of Stock

Choludexan instructionReed more and buy CholudexanCompositionOne capsule of Choludexan contains 300 mg of UDCA (ursodeoxycholic acid).Form of issueCholudexan is manufactured in the form of capsules, which are packaged in aluminum ..

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Choludexan instruction

Reed more and buy Choludexan


One capsule of Choludexan contains 300 mg of UDCA (ursodeoxycholic acid).

Form of issue

Choludexan is manufactured in the form of capsules, which are packaged in aluminum blisters for 10 pcs. in each, and then put in cardboard packages of 2 blisters in each. A total of 20 capsules of the drug are contained in one cardboard pack.

pharmachologic effect

Pharmacists consider this drug to be hepatoprotective medicine.

Pharmacodynamics and pharmacokinetics

Since Choludexan belongs to the hepatoprotective medicine, the drug has choleretic properties, and also promotes the formation and further dissolution of the human body of stones (ie stones). In addition, the drug has immunomodulatory, lipid-lowering, cholelitholic and hypocholesterolemic properties.
The ursodeoxycholic acid (UDCA), which is part of the drug, promotes the formation of non-toxic micelles (mixed) with apolar bile acids, thus neutralizing the negative effect of gastric reflux on the cell membranes in relluxesophageitis and reflux gastritis.
Under the influence of UDCA in the human body, molecules are formed that are embedded in the membranes of cells-cholangiocytes, hepatocytes and gastric epitheliocytes, stabilizing them and making them immune to harmful cytotoxic micelles. Ursodeoxycholic acid reduces the concentration of bile acids that destroy liver cells and lead to the stimulation of choleresis, which in turn is characterized by the presence of a large amount of bicarbonates.
A highly active compound that is part of Choludexan reduces cholesterol in the bile, thus inhibiting its absorption by the stomach, as well as synthesis in the liver. UDCA reacts with cholesterol and increases its solubility in bile, eventually forming crystals and decreasing the lithogenic index. Ultimately, under the influence of Cholodexan, gallstones dissolve.
In the course of laboratory studies, it was found that the drug effectively blocks fibrosis in patients suffering from cirrhosis, alcoholic steatohepatitis, cystic fibrosis. In addition, this medicine prevents the development of varicose veins in the esophagus and slows premature aging, as well as the death of cholangiocytes, hepatocytes and other cells.

Indications for use

Choludexan shows:
    with active chronic hepatitis;
    with cholelithiasis;
    with liver damage caused by toxins, for example, under the influence of drugs;
    with ABP (alcoholic liver disease);
    cirrhosis of the liver (biliary, primary);
    atresia, including congenital, affecting the bile duct;
    cystic fibrosis;
    reflux gastritis and esophagitis;


Choludexan is contraindicated:
    with dysfunction of the gallbladder;
    if the patient has X-ray positive gallstones, i.e. containing a large amount of calcium;
    with cholecystitis of acute type;
    in the presence of a bile-gastric fistula;
    with acute stage cholangitis;
    in the presence of infectious diseases of the intestine, gallbladder and ducts in the acute stage;
    with cirrhosis in the stage of decompensation;
    with renal or hepatic insufficiency;
    with empyema of the gallbladder;
    with hypersensitivity.
In addition, the drug is contraindicated in children under the age of 4 years.

Side effects

With the use of this drug, there may be side effects such as: exacerbation of psoriasis, nausea, diarrhea, back pain, vomiting, constipation, alopecia, transient increase in the transmissar activity of the liver.

Choludexan, instructions for use (Method and dosage)

Instruction for the use of Choludexan prescribes the use of the drug according to the following schemes:
    course from 10-14 days to 6-24 months for 1 capsule (300 mg) a day before bedtime with reflux gastritis or esophagitis;
    continuous course for several months to 2 years for 2-5 capsules per day - with cholelithiasis, with chronic liver disease, with biliary sludge and cholesterol gallstones to complete dissolution of stones and another three months after the main course of treatment with a view to prevention of neoplasms;
    in a daily dosage of 10-15 mg. for each kg. weight in the treatment of biliary cirrhosis for at least six months;
    steatohepatitis not associated with alcohol is treated with the drug in a daily dosage of 13-15 mg per kg of the patient's weight for 6-24 months;
    course for several months of 2 capsules per day for the prevention of cholelithiasis and cholecystectomy;
    for 6-12 months, 10-15 mg per kg of body weight per day for liver damage caused by exposure to toxins or drugs, with atresia;
    for the treatment of cystic fibrosis apply a dosage of the drug equal to 20-30 mg per kg of weight per day for 6-24 months;
    with cholangitis use a daily dosage of 12-15 mg (maximum 20 mg) for 6-24 months.
When treating children who have reached the age of 4, it is recommended to use the dosage of Choludexan equal to 10-20 mg per day for each kg of the patient's weight.


Reduce the absorption of the drug drug compounds containing antacids, i.e. ion exchange resins, colestyramine, aluminum.
Decrease the solubility of stones hypolipidemic drugs, in particular Neomycin, Clofibrate estrogen and Progestin.
Choludexan enhances the properties of hypoglycemic drugs intended for oral use.

Storage conditions

It is recommended that the medicine be kept away from children, at 15-20 ° C.
Shelf life - 3 years.

special instructions

In order to avoid negative consequences for the health of the patient when using the drug for the purpose of dissolving stones, it should be remembered that gallstones should be referred to as X-ray or cholesterol, their size should not be more than 20 mm. In addition, the gallbladder should be filled with stones no more than half and should function, the patency of the bile common flow should be preserved.
To determine the activity of liver transaminases during a long course of therapeutic treatment with the drug (over one month), a biochemical blood test should be carried out continuously. Every six months, ultrasound and x-ray of the bile ducts should be performed to determine the degree of effectiveness of the drug.
If during half a year from the beginning of the use of the medicinal product, at least partial dissolution of the stones did not occur, then the effectiveness of further treatment is extremely small, and the attending physician should prescribe other medications to the patient.


Choludexan is used in pediatrics in the treatment of patients who have reached the age of 4, in the dosages specified in the instructions for use of the drug.

In pregnancy and lactation

According to the general rules, it is not recommended to use Choludexan in the treatment of pregnant women, however, in case of acute medical necessity, the drug may be prescribed by the attending physician if the expert is sure that the prospective benefit from it will significantly exceed the likely negative consequences. It is also not recommended to use the drug during breastfeeding.

Reviews of Choludexan

As with most drugs on the Internet, it is possible to get acquainted with both positive and negative opinions of patients about this drug.
The drug acts on each patient in different ways, so it helps one, and the other does not. The doctors' comments about Cholodexan are extremely rare and are rather generalized.

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