Glutargin Alcocline powder 1gr/3gr #2

Glutargin Alcocline user manual

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Composition

It is worth noting that the chemical composition of Glutargin depends on the form of release of the drug.
In one tablet Glutargin Alcocline contains one gram of active compound, and in one packet of powder, intended for preparation of a solution for subsequent ingestion - 1 gram.

Form of issue

Tablets and powder Glutargin Alkoklin for solution is packaged in contour blisters for 2 or 10 pieces, as well as special sachets of 3 or 6 grams each (respectively). Then place the tabletted drug in cardboard boxes with 1 blister in each, and a powdered mix in packs of 2, 5 or 10 bags (3 or 6 grams each) in each.

pharmachologic effect

Both Glutargin and Glutargin Alkoklin belong to the hypoammonemic group of drugs that have hepatoprotective pharmacological properties.

Pharmacodynamics and pharmacokinetics

Active drug glutargin or alkoklin, which is part of these drugs, is a product of the interaction of glutamic acid and arginine. This compound plays an important role in the neutralization of ammonia, which in turn is a highly toxic metabolite, formed in the human body as a result of the interaction of nitrogen-containing substances.
In addition, glutargin promotes the rapid removal of this poisonous and deadly compound for health from the body. Due to the unique properties of the active substance included in the chemical composition of the drug, both Glutargin and Glutargin Alkoklin have hepatoprotective, as well as antihypoxic and antioxidant effects.
Both drugs exhibit membrane-stabilizing activity, thereby exerting a positive effect on hepatocytes, thus supporting energy-supplying processes that occur in them every second. Glutargin Alkoklin is simply irreplaceable for alcohol intoxication.
The drug effectively stimulates the breakdown of alcohol in the liver with the help of a monooxygenase system, and also enhances the production of alcohol dehydrogenase, i.e. an enzyme that promotes the "utilization" of ethanol in the human body. The drug accelerates the process of excretion of metabolites of ethanol and enhances inactivation, while increasing the production of succinic acid.
Thus, the influence of alcoholic beverages on the human nervous system is reduced due to the unique neurotransmitter properties of glutamic acid. Drugs do not have mutagenic, embryotoxic or gonadotoxic effects, nor do they cause immunotoxic or allergic reactions in patients.

Indications for use

Glutargin is used to treat:
    hepatitis, including acute or chronic forms of the disease, various etiologies;
    cirrhosis of the liver;
    hepatic encephalopathy;
    consequences of poisoning with poisons contained in plant material, for example, Pale grebe, as well as in medicines and chemicals;
    leptospirosis;
    states of precoma or coma, provoked by hyperammonemia;
    alcohol poisoning, including alcoholic coma and encephalopathy;
    disorders postintoksikatsionnogo nature, caused by the use in large doses of alcoholic beverages.
In addition, this drug is often included in the complex therapeutic treatment of alcoholism, as it helps to eliminate the consequences of "hangover syndrome", intoxication, and also strong alcohol intoxication.
Glutargin Alkoklin is used for:
    prevention of alcoholism;
    treatment of acute forms of alcohol poisoning, as well as postintoxication disorders.

Contraindications

Both drugs are not recommended for use during treatment of people under the age of 18, pregnant or breast-feeding women, patients with febrile status, and those with renal impairment, namely, the nitrogen excretory filtration capacity of the organ. In addition, drugs are contraindicated in acute psychoses and increased excitability.

Side effects

Rarely, however, when taking drugs, the following side effects may occur:
    a feeling of discomfort in the intestine;
    heaviness in the stomach;
    nausea.
The above-listed side effects of drugs disappear immediately after discontinuation of use of medicines.

Instructions for use Glutargin (Method and dosage)

A solution or concentrate of Glutargin (ampoules of 2 grams), intended for infusions, is administered intravenously twice a day at an average rate of 70 drops per minute. To prepare the solution, the drug compound contained in the ampoules is mixed with 250 ml. sodium chloride (isotonic). As a rule, the course of treatment with the drug is on average 5-10 days. The recommended maximum daily dosage should not exceed 8 grams.
To prevent hepatotoxic effects of alcohol on the body, and also for the purpose of preventing alcohol intoxication, Glutargin Alcocline tablets take two pieces at a maximum of two hours prior to direct consumption of alcoholic beverages. A powder containing an active compound is dissolved in ½ a glass of water before use and is also taken two hours before the direct use of alcohol.
When treating the effects of alcohol intoxication, tablets or powder Glutargin Alcocline take one or a packet (respectively) four times a day at intervals of two and a half hours, and then for another 3 days - one piece or sachet twice a day . With a severe degree of alcohol poisoning, the drug is taken one tablet or a packet of powder twice a day for 20 days.

Overdose

In the event that the recommended dosages for these medicines are exceeded, symptoms such as headache, vomiting, hypotension, insomnia, lowering blood pressure, and atrioventricular (AV) blockade or allergic reactions may occur. In such cases, you should immediately stop taking medications, and then conduct symptomatic treatment of patients.

Interaction

To avoid undesirable strengthening or weakening of the effectiveness of drugs, increasing the level of insulin in the blood and reducing neurotoxic phenomena with caution, Glutargin and Glutargin Alcocline should be taken together with antiplatelet drugs, for example, with Dipiridamol, and also with Isoniazid, Aminophylline and Vinblastine.

Terms of sale

You can buy this drugs without a prescription.

Storage conditions

Both of these preparations should be stored in a place inaccessible to children, at a temperature not exceeding 25 ° C.
Shelf life - 2 years

special instructions

To exclude the negative effect that is expressed in increasing the level of insulin in the blood, with special care, both drugs should be prescribed for patients suffering from endocrine system diseases. Both do not affect the ability of patients to drive vehicles, as well as work with potentially dangerous mechanisms.

Children

Both drugs are not used in the treatment of patients under 18 years of age.

In pregnancy and lactation

Since to date, experts do not have reliable data on the effect of drugs on the development and health of the unborn child, these drugs are not recommended for pregnant women, as well as for nursing mothers.

Reviews about Glutargin

Most of the reviews about Glutargin are positive. Patients note the effectiveness of Glutargin tablets, which can cope well with liver diseases, as well as with the consequences of alcohol intoxication, as well as poisoning, including severe forms. Many note the indispensability of the drug for a hangover.
It is worth noting that those patients who took Glutargin Alkoklin, reviews about the drug leave good, noting among the obvious advantages of the drug, a small list of side effects, as well as contraindications to use.