Heptral 400mg #20

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Heptral instruction for use

The drug Heptral is a drug from the group of hepatoprotectors, which, in addition to its basic therapeutic effect, has even more pronounced antidepressant activity.

Form of formulation and composition of the preparation

Heptral is available in the form of tablets for oral administration. Each tablet is covered with a protective coating of white with a slightly yellowish tinge. The main active substance of the drug is ademethionine, as auxiliary components are: colloidal silicon dioxide, microcrystalline cellulose, magnesium stearate.
Tablets are packed in blisters of 10 pieces with 2 blisters in a cardboard bundle.

Pharmacological properties of the drug

The drug Heptral is used inside. The active substance of the tablets restores hepatocytes, as well as impaired liver function. The drug has a pronounced antioxidant, regenerating and neuroprotective properties.
Adenomethionine takes an active part in the most important metabolic processes and is necessary for the full production of amino acids and hormones by the body. The drug improves the gallbladder and improves the process of gallbladder outflow.
Active components of the drug create an invisible protective barrier on the surface of the liver, which protects hepatocytes from the negative effects of other drugs or poor-quality food.
Patients with chronic diseases of the liver and bile ducts noted a significant improvement in the general condition, the disappearance of pruritus, severity and pain in the region of the right hypochondrium, the taste of bitterness in the mouth against the background of taking the tablets Heptral. The parameters of the biochemical blood test also returned to normal, in particular, the level of hepatic transaminases, bilirubin, creatinine.
Antidepressant properties of this hepatoprotector begin to appear after 2 weeks from the start of therapy.

Indications for use of the drug

Tablets Heptral are prescribed to patients for the treatment and prevention of the following conditions:
    Chronic inflammatory processes in the liver and bile ducts - hepatitis, cirrhosis, cholangitis and cholecystitis;
    Liver failure on the background of intoxication of the body, including poisoning with alcoholic beverages;
    Toxic liver damage - drugs, viruses, alcohol, hormonal drugs, poor-quality food;
    Depressive states in the complex therapy.

Contraindications to use

Before starting therapy with this drug, you should carefully read the instructions, since the tablets have a number of serious contraindications. Contraindications include:
    Children under 18 years;
    Individual intolerance to the components of the drug;
    Congenital disorders of metabolic processes in the body, including a violation of absorption of vitamin B12.

Dosing and Administration

Heptral tablets are for oral use. The drug should be swallowed immediately, without chewing, squeezed with enough liquid. Tablets are recommended to be taken between meals.
According to the instruction, patients with liver and biliary duct function disorders are prescribed 1 tablet of the drug 1-3 times a day, depending on the severity of the clinical manifestations of the pathology. The duration of therapy with this drug is determined by the physician in a strictly individual order.

Use of the drug during pregnancy and lactation

Despite the fact that animal studies have not revealed any abnormalities in the fetus when using the drug Heptral in the first trimester of pregnancy, treatment with this hepatoprotector in the first 12 weeks is still not recommended.
The use of tablets of this drug in the 2nd and 3rd trimesters is possible only after a careful evaluation of the benefits to the mother and the risk to the fetus.
Use of tablets Heptral during breastfeeding is possible after preliminary consultation with the doctor and under his strict control.

Side effects

On the background of drug therapy in patients often developed side effects, which include:
    On the part of the digestive organs: nausea, upset of the stool, flatulence, abdominal pain;
    Disturbances in the work of the kidneys;
    Disturbance of respiratory function;
    Decrease in blood pressure;
    Dyspnea;
    Increased heart rate;
    Pain in the heart;
    Muscle and joint pain;
    Chills;
    Lack of appetite;
    General malaise and weakness;
    Allergic skin reactions - itching, redness, urticaria, local fever, in very rare cases, the development of angioedema.

An overdose of the drug

If the dose or prolonged uncontrolled use is exceeded, the patient may develop an overdose that manifests itself in the form of an increase in the side effects described above. The antidote of the drug does not exist. In case of an overdose with Heptral, the patient should be given to take enterosorbents and sent to a doctor.

Interaction with other medicinal products

This drug is well combined with most drugs, moreover, Heptral tablets significantly reduce the negative effects of drugs on liver cells and reduce the risk of side effects on therapy.
With special care, this drug should be given to patients who are already taking any antidepressant or psychotropic medicinal substances.

special instructions

Since the active substances of the drug tonic affect the central nervous system, Tablets Heptral is not recommended before bedtime, as this can lead to insomnia. The last dose should be no later than 4 hours before bedtime.
With prolonged use of this hepatoprotector, patients with cirrhosis or other functional disorders in the liver should regularly monitor the blood test and general condition of the patient.
Patients with severe disturbances of the psyche accompanied by suicidal thoughts, the drug is not prescribed or prescribed with extreme caution. In the event of a deterioration in the mental state of the patient or the development of severe depression, treatment with the drug is canceled.
Against the background of taking this medication, the patient may experience dizziness, therefore Heptral tablets should be used with caution by vehicle drivers or persons whose work requires increased concentration of attention.
The drug is not used in pediatric practice.

Conditions of drug storage

The drug should be stored in a place protected from children at a temperature of not more than 20 degrees. The shelf life of the tablets is indicated on the package, after which it should be discarded.