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Maalox suspension 4.3ml #6

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  • $8.20
  • 3 or more $7.99
  • Availability:In Stock

Maalox suspension instruction for useYou can buy Maalox suspension herepharmachologic effectAntacid preparation. Neutralizes free hydrochloric acid of gastric juice without causing its secondary hypersecretion. In addition, an inc..

Maalox suspension instruction for use

You can buy Maalox suspension here

pharmachologic effect

Antacid preparation. Neutralizes free hydrochloric acid of gastric juice without causing its secondary hypersecretion. In addition, an increase in the pH of gastric juice when taking Maalox leads to a decrease in the activity of pepsin in gastric juice. The drug also has an adsorbent and enveloping action, due to which the effect of damaging factors on the mucous membrane of the esophagus and stomach decreases.

Pharmacokinetics

Magnesium hydroxide and aluminum hydroxide are considered local action antacids, which are practically not absorbed when taken in recommended doses and, accordingly, do not have systemic effects.

Indications

- Stomach ulcer and duodenal ulcer in the phase of exacerbation;
- Acute gastroduodenitis;
- chronic gastroduodenitis with normal or increased secretory function in the exacerbation phase;
- hernia of the esophageal aperture of the diaphragm;
- reflux esophagitis;
- Dyspeptic phenomena, such as discomfort, gastralgia, heartburn, acidic eructations (after excess consumption of ethanol, nicotine, coffee, taking medicines (including NSAIDs, GCS), inaccuracies in the diet).

Contraindications for Maalox suspension

- severe renal failure;
- hypophosphatemia;
- intolerance to fructose;
- glucose-galactose malabsorption syndrome, sugarase / isomaltase insufficiency, (due to the presence of sucrose in the formulation) (for chewing tablets);
- intolerance to maltitol (for chewing tablets without sugar);
- children and adolescence up to 15 years;
- Hypersensitivity to active substances and other components of the drug.
With caution should be used in patients with porphyria, who are on hemodialysis; Alzheimer's disease; during pregnancy; for chewing tablets - for diabetes mellitus (due to the presence of sucrose in the formulation).

Dosage of Maalox suspension

Maalox suspension in bags

Before use, Maalox suspension in the bag should be homogenized, carefully stretching it between the fingers. The contents of the sachet are taken in an undissolved form.
Maalox take 1 packet with a suspension (15 ml), usually 1-2 hours after meals and at night, as well as when epigastric pain or heartburn occurs. The daily dose should not exceed 6 packets (90 ml of suspension per day).
When reflux-esophagitis the drug is taken 30-60 minutes after eating.
With gastric ulcer, the drug is taken 30 minutes before meals.
The course of treatment should not exceed 2-3 months.
With occasional use, for example, with discomfort after errors in the diet, take 15 ml once.

Maalox suspension in vials

Before use, the vial should be shaken.
Assign 15 ml (1 tablespoon) 3-4 times a day 1-2 hours after meals and at night. The dose should not exceed 6 tablespoons per day.
When reflux-esophagitis the drug is taken a short time after eating.
The course of treatment should not exceed 2-3 months.
With occasional use, for example, with discomfort after errors in the diet, take 15 ml once.
In patients with impaired renal function, Maalox should be avoided at high doses and / or for a long time.

Side effects of Maalox suspension

While observing the recommended dosing regimen, side effects are negligible.
Definition of the frequency of adverse effects (according to WHO classification): infrequently (≥0.1% and <1%); the frequency is unknown (it is not possible to estimate the incidence from the available data).
On the part of the immune system: the frequency is unknown - hypersensitivity reactions, anaphylactic reactions.
Allergic reactions: the frequency is unknown - itching, hives, angioedema.
From the digestive system: infrequently - diarrhea, constipation.
From the side of metabolism: frequency is unknown - hypermagnesia, hyperaluminia, hypophosphatemia (with long-term treatment or intake in high doses, or when taken in standard doses at low phosphate levels in food), which can lead to increased bone resorption, hypercalciuria, osteomalacia.


Overdose

Symptoms: diarrhea, abdominal pain and vomiting are possible. In patients at risk of taking the drug in high doses can cause or aggravate bowel obstruction or intestinal obstruction.
Treatment: aluminum and magnesium are excreted in the urine. A loss of fluid and forced diuresis are performed. Patients with renal failure need hemodialysis or peritoneal dialysis.

Drug Interactions

With simultaneous application with quinidine, it is possible to increase the serum concentrations of quinidine and the development of an overdose of quinidine.
With the simultaneous administration of the Maalox drug, the absorption of the following drugs is reduced from the gastrointestinal tract: histamine H2 receptor blockers, propranolol, atenolol, cefdinir, cefpodoxim, metoprolol, chloroquine, prostacyclin, diflunizal, digoxin, bisphosphonates, ethambutol, isoniazid, fluoroquinolones, sodium fluoride, GCS (described for prednisolone and dexamethasone), indomethacin, ketoconazole, lincosamides, neuroleptics of phenothiazine derivatives, penicillamine, rosuvastatin, iron salts, levothyroxine sodium. In the case of a 2-hour interval between the administration of these drugs and the Maalox preparation and the 4-hour interval between the intake of fluoroquinolones and Maalox preparation in most cases, this undesirable interaction can be avoided.
When using Maalox with polystyrene sulfonate (cayexalate) together, care should be taken because of the possible risk of decreased potassium binding potency and metabolic alkalosis in patients with renal insufficiency (for aluminum hydroxide and magnesium hydroxide) and intestinal obstruction (for aluminum hydroxide).
When aluminum hydroxide is combined with citrates, it is possible to increase plasma concentrations of aluminum, especially in patients with renal insufficiency.

special instructions for Maalox suspension

Aluminum hydroxide can cause constipation, an overdose of magnesium salts can lead to a weakening of intestinal peristalsis; in patients from the high-risk group (patients with renal insufficiency, elderly people), taking high doses of the drug may cause or aggravate bowel obstruction and intestinal obstruction.
Aluminum hydroxide is poorly absorbed from the digestive tract, therefore in patients with normal renal function systemic exposure is rare. However, long-term treatment, the use of the drug in excessively high doses, or the use of the drug in usual doses against the background of a decrease in the intake of phosphates with food, can lead to phosphate deficiency (due to binding of aluminum to phosphate), which is accompanied by increased bone resorption and hypercalciuria with a risk of developing osteomalacia. Treatment of patients at risk of developing phosphate deficiency or prolonged use of the drug should be performed under medical supervision.
With renal insufficiency, an increase in plasma concentrations of magnesium and aluminum is possible. In these patients with prolonged use of Maalox suspension in high doses, it is possible to develop encephalopathy, dementia, microcytic anemia or aggravation of osteomalacia caused by dialysis.
If, during treatment, symptoms from the GI tract persist for more than 10 days or if the condition worsens, then the diagnosis should be clarified and treatment adjusted.
A 2-hour interval between use of Maalox suspension and other drugs should be observed.
Avoid prolonged use of Maalox suspension in renal failure.
Despite the fact that the drug is dispensed without a prescription, before using the drug during pregnancy and lactation (breastfeeding), as well as in adolescents, it is recommended to consult a doctor.
Aluminum hydroxide with a low phosphate content in food can lead to the development of phosphorus deficiency in the body. Therefore, when it is used, especially long-term, it is necessary to ensure sufficient supply of phosphates with food.
The drug is permeable to X-rays.
When using the drug in patients with diabetes mellitus, the presence of sucrose in the tablets of Maalox chewable preparations should be taken into account.
Impact on the ability to drive vehicles and manage mechanisms
The drug does not affect the ability to drive vehicles and work with mechanisms.

Pregnancy and lactemia

To date, no specific teratogenic effects have been identified with the use of Maalox suspension during pregnancy, however, due to the lack of clinical experience of its use in pregnancy, appointment is possible only if the potential benefit of therapy for the mother justifies the potential risk to the fetus.
When using the drug in accordance with the dosing regimen, the absorption of aluminum hydroxide and magnesium salts in the mother's body is limited, so Maalox suspension is recognized as compatible with breastfeeding.
In pre-clinical studies in animals, there is no clear indication of a teratogenic effect in aluminum hydroxide and magnesium hydroxide.

Application in childhood

Contraindicated in children and adolescents under the age of 15 years.

In case of violations of kidney function

Contraindicated in severe renal failure.

Application in old age

In elderly patients, the use of the drug in high doses can cause or aggravate bowel obstruction and intestinal obstruction.

Conditions of leave from pharmacies

You can buy Maalox suspension without a prescription.

Terms and conditions of storage

The drug should be stored out of reach of children at a temperature of no higher than 25 ° C.
Shelf life for chewable tablets is 5 years, for chewing tablets (without sugar) - 3 years; for Maalox suspension in bags - 3 years, in bottles - 30 months. Shelf life of the suspension after the first opening of the vial is 6 months.

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