Normase syrup 200ml

Normase user manual

Reed more and buy Normase

Composition

The syrup contains lactulose (active substance), as well as flavoring, citric acid (additional substances).

Form of issue

The syrup has a liquid syrupy consistency, it is transparent or has a light yellow hue, a characteristic sweet aroma. Contained in bottles of dark glass of 200 ml, also in a cardboard package contains a measuring cup of polyethylene.

pharmachologic effect

Normase acts on the body as a laxative, providing an osmotic laxative and hypoammonemic effect. Lactulose is a synthetic oligosaccharide, in which there are residues of galactose and fructose.
Enzymes that are able to split lactulose, in the human body there. Therefore, this substance remains unchanged under the influence of acidic and alkaline media, therefore, in the large intestine it appears unchanged.
After entering the large intestine, lactulose is exposed to a specific microflora, followed by a hydrolysis process followed by the formation of organic acids. The main metabolite of lactulose is lactic acid, and its metabolites are formic and acetic acids.
Under the influence of lactulose, the level of osmotic pressure in the large intestine increases, which facilitates the ingress of fluids into the large intestine from the blood. This, in turn, determines the increase in the volume of feces, their significant softening. In view of the increase in the volume of fecal matter, stimulation of intestinal peristalsis occurs.
When it enters the large intestine, lactulose creates an acidic environment in it, stops the development and growth of pathogenic microflora. It is in an acidic environment that lacto - and bifidobacteria most actively multiply. Consequently, under the influence of lactulose, the microflora is restored and its normal balance is maintained. This helps maximize the full absorption of nutrients, in particular, calcium salts, phosphates, normalization of metabolic protein processes, activation of the synthesis of a number of vitamins, which produces intestinal microflora.
Also, lactulose increases the level of bile secretion in the intestine, activates the transition from the blood of ammonia to the lumen of the intestine, its ionization. Under the influence of lactulose, the content of toxins in the blood, in particular ammonia, decreases. In this case, the liver works with less intensity, which positively affects the condition of people with impaired liver function.

Pharmacodynamics and pharmacokinetics

The drug increases the level of acidity in the large intestine and stimulates the intestinal peristalsis, softening the stool masses. The laxative effect is without affecting smooth muscle and intestinal mucosa.
The action of the drug occurs 24-48 hours after its oral administration, since initially the drug completely passes through the human gastrointestinal tract.
There is a low level of adsorption of lactulose metabolites in the blood, about 8% of metabolites are excreted in the urine. Basically, the drug is excreted from the body with feces.

Normase inhibits the growth of salmonella in the large intestine. Addiction to the drug is not noted, it does not reduce the absorption of vitamins.

Indications for use

Normase is prescribed for the treatment of the following conditions:
    Chronic constipation: used for babies, elderly people, pregnant women.
    Hepatic encephalopathy: used for the purpose of therapy and prevention of coma and precoma in patients with hepatic encephalopathy.
    Disturbances of microflora in the large intestine: among other things, is used in the detection of salmonella.
    Dysbacteriosis: after treatment with antibiotics, with eating disorders.
    It is used before and after surgical intervention to regulate stool in patients with hemorrhoids.
    The syndrome of putrefactive dyspepsia: including manifested due to food poisoning, is used to treat young children.
    Hyperammonemia.
Also, the drug is used in the complex treatment of vaginal candidiasis, vaginal dysbacteriosis, osteoporosis.

Contraindications

Do not practice treatment Normase in the following cases:
    high sensitivity to the ingredients of the product;
    intolerance to galactose, fructose;
    bleeding in the intestine;
    galactosemia;
    intestinal obstruction;
    presence of suspicion of appendicitis;
    chronic appendicitis.
With care, Normase is used to treat patients with diabetes mellitus.

Side effects

Possible manifestations of the following side effects:
    nausea, diarrhea, flatulence;
    violation of water-electrolyte metabolism (with prolonged therapy);
    dizziness, headache;
    myalgia, arrhythmia;
    weakness, a sense of fatigue.

Instructions for use Normase (Method and dosage)

If the patient is prescribed Normase, the instructions for use should be carefully followed. Syrup should be drunk after eating.
Instructions for use Normase with constipation provides that adult patients take in the first three days of treatment for 15-40 ml every day, in the following days the dose is 10-25 ml daily.
Children after 6 years, as well as adolescents receive 15 ml every day for the first three days, then the drug is prescribed in a dose of 10 ml per day.
Children aged 1-6 years should take 5-10 ml per day. Children under 1 year take Norma 5 ml per day.
Depending on the general state of human health and the course of his illness, the course of treatment can last from 1 to 4 months.
Patients who are diagnosed with hepatic coma, precoma, encephalopathy or an elevated level of ammonia in the blood are prescribed Norma in a dose of 30-60 ml three times a day. Further the dosage is determined so that a person has a mild stool 2-3 times a day. The process of treatment with the drug continues for at least three months.
After performing surgical interventions Norma needs to be taken after 18 hours, after which the treatment lasts 3-5 days. Adult people take 10-30 ml of Norma thrice a day, children after 1 year - 5-10 ml 2-3 times a day. Children under 1 year should take 5 ml of Norma 2-3 times a day.

Overdose

There were no cases of overdose of Normase.

Interaction

With simultaneous administration with antibiotics and antacids, the effectiveness of Normase decreases. Under the influence of lactulose, the release of drugs that have a dependence on the pH of the medium changes.

Normase should be taken no sooner than two hours after the use of any medication.

Terms of sale

You can buy online Normase without a doctor's prescription.

Storage conditions

Store the product at a temperature of 15 to 25 ° C. It can not be frozen. Norma should be protected from children.
Shelf life - 3 years.

special instructions

If long-term treatment lasts for more than 6 months, it is necessary to regularly determine the level of chlorine, potassium, carbon dioxide in the blood.
Patients suffering from gastrocardial syndrome should increase the dose gradually to prevent the manifestation of flatulence.

Which is better: Dufalac or Normase?

Very often parents have doubts about which drug is better to choose for the treatment of a child - Dufalac or Normase. There is no particular difference between these drugs, since both drugs are based on a similar active ingredient, lactulose. Therefore, they affect the organism of the child and the adult patient in the same way.

Newborns

Normase for newborns is used if they have constipation associated with various diseases or features of the body. When using the means for newborns, the parents' testimonies indicate that Normase effectively removes constipation associated with the feeding habits of the nursing mother and baby, problems in the introduction of complementary foods, transfer to artificial feeding, etc.

Normase is a natural bifidogenic agent, so it can be used without restriction for newborns. Treatment should begin with minimal doses, while observing the state of the baby. Normase does not provoke addiction, has a pleasant taste and smell.

Normase in pregnancy and lactation

You can apply Normase in pregnancy, as it does not have a negative effect on the fetus. In the general bloodstream lactulose does not fall, so the systemic effect on the body does not. Reviews during pregnancy are mostly positive, as the drug helps to effectively eliminate constipation, which is a frequent problem for a woman expecting a child.
In addition, Normase has a positive effect on the state of the microflora of the vagina, preventing ascending infections. When breastfeeding, Normase is also prescribed.

Reviews about Normase

Reviews about Normase in the network are mostly positive, it is often used both for the treatment of adults, and for children, in particular newborns. Those parents who used the drug for children, reviews about Normase often write about the fact that the drug is well tolerated, does not cause negative effects and allows you to get rid of even chronic constipation. It is noted that the remedy should be used exactly as prescribed by the doctor.
Also, those who used the remedy for the treatment of children and newborns, the reviews wrote, and that the drug is delicious and well received by children. In general, positive impressions about the treatment of Normase remained in pregnant women who with it helped get rid of constipation.