Cyanocobalamin solution 500mcg 1ml #10

Cyanocobalamin user manual

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Composition

Vitamin B12, water for injection, sodium chloride.

Form of release of Cyanocobalamin

Solution for injections in concentration 0.02%, 0.05% in ampoules of 1 ml, packing - in carton No. 10.

pharmachologic effect

Cyanocobalamin is a biologically active drug that has a hemopoietic, erythropoietic, metabolic and anti-anemic effect. Accelerates the processes of tissue healing, normalizes the work of the central nervous system and hematopoiesis system, improves the processes in the liver, enhances the activity of thromboplastics and prothrombin, activates the blood clotting process, reduces the amount of cholesterol in the blood.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Activates the exchange of proteins, fats and carbohydrates. Forms an energy reserve in the body and actively participates in the process of transmission of nerve impulses. It is part of the phosphocreatine and promotes the accumulation of hemoglobin in erythrocytes. Stimulates the bone marrow (normoblastic erythropoiesis). This drug normalizes the liver, has a positive effect on the blood clotting system, in high doses increases the activity of prothrombin.

Pharmacokinetics

The drug is absorbed mainly in the thin (less in the thick) intestine, then through the receptor system is transported to the cell. In the blood it combines with the trans-balanamines I and II, and then it is transported to tissues where it is metabolized. In the body, this vitamin is deposited in the liver. It is excreted from the body by a renal excretory system.

Indications for use of the drug

    iron deficiency anemia of various origins;
    folate deficiency and vitamin deficiency anemia;
    cirrhosis of the liver;
    dystrophy in young children;
    motor neuron disease;
    lumbosacral radiculitis;
    cerebral palsy in children;
    defeat of the trigeminal nerve;
    multiple sclerosis;
    polyneuropathy;
    chronic hepatitis;
    Down syndrome;
    neuralgia, neuritis;
    skin diseases (psoriasis, eczema).

Contraindications

Angina pectoris, thromboembolism, erythremia (Vakez disease) erythrocytosis (elevated red blood cell content).
Side effects
Mental exaltation, tachycardia, allergic reactions, dizziness, headache, diarrhea.

Instructions for use Cyanocobalamin (method and dosage)

Enter the drug intramuscularly, intravenously, subcutaneously and intraljumbally. Therapy Ciancobalamin is accompanied by regular monitoring of coagulation rates and the general picture of blood. Doses of the drug depend on the specific disease:
    with aplastic anemia, 100 μg every other day is administered until a hematologic and clinical improvement is obtained;
    with iron deficiency and posthemorrhagic anemia - 30-100 mcg three times a week;
    Anemia in children - 40 mcg per day for 15 days;
    neurological traumatic diseases and diseases of the nervous system - in increasing doses from 250 to 500 mcg, the duration of treatment - up to 2 weeks; with the improvement of the patient's condition - 100 mcg per day;
    lesions of peripheral nerves caused by trauma - 200-400 mcg every other day for a month and a half;
    Down's disease, cerebral palsy and dystrophy in children - 15-30 micrograms per day;
    diabetic neuropathy, radiation sickness - 60-100 micrograms a month.
    hepatitis and cirrhosis - 100 mcg per day for 30 days;
    funicular myelosis, multiple sclerosis - introduce 15-30 μg of the solution, increasing the dose gradually from 200 to 500 μg.

Overdose

Possible development: pulmonary edema, peripheral vascular thrombosis, urticaria, less often, anaphylactic shock.

Interaction

Cyanocobalamin is a vitamin that is incompatible with thiamine bromide, riboflavin and pyridoxine (in one syringe). At simultaneous appointment with antibiotics (kanamycin, polymyxins, neomycin and tetracyclines), the absorption of this drug is difficult. Do not take together with drugs that affect blood clotting. Therefore, if you are prescribed Cyanocobalamin, the instructions for use should be carefully studied.

Storage conditions

Cyanocobalamin (vitamin B12) preparation list B .: storage temperature 2 - 20 ° C in a dark place.
Shelf life - Two years

In pregnancy

Use with caution during pregnancy due to possible teratogenic effects of large doses of B vitamins on the fetus.

Reviews of Cyanocobalamin

Reviews about the drug are mostly positive. Patients note that after the course of treatment hemoglobin rises, normalizes well and sleep improves, depression passes, pains decrease with neuralgia and inflammation of the trigeminal nerve.
According to the patients' reviews Cyanocobalamin in ampoules is an effective tool for hair. Many women are interested in how to use Cyanocobalamin for hair? Like all B vitamins, it has a positive effect on the hair. Even regular (once a week) injections of the drug help to strengthen the roots of hair, reduce their loss. The drug is often used as a component of hair masks or in its pure form for rubbing into the roots of hair.