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Bisoprolol tabs 10mg #50

  • $27.54
  • 3 or more $27.25
  • Availability:In Stock

Instruction for BisoprololReed more and buy Bisoprolol onlineCompositionOne Bisoprolol tablet contains 5 mg or 10 mg of bisoprolol hemifumarate and bisoprolol fumarate in a 2: 1 ratio as active ingredients.Excipients: calcium hydr..

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Instruction for Bisoprolol

Reed more and buy Bisoprolol online


One Bisoprolol tablet contains 5 mg or 10 mg of bisoprolol hemifumarate and bisoprolol fumarate in a 2: 1 ratio as active ingredients.
Excipients: calcium hydrogen phosphate, corn starch, colloidal silicon dioxide, microcrystalline cellulose, crospovidone, magnesium stearate.
Sheath composition: hypromellose, dimethicone, iron oxide yellow, macrogol 400, titanium dioxide.

Form of issue

Bisoprolol tablets are covered with a light orange shell, heart-shaped, biconvex, with serrations on both edges.
Form release for Bisoprolol (dosage of 5 and 10 mg):
    ten such tablets in a blister, five or three such blisters in a carton;
    or 25 such tablets in a blister, two such blisters in a carton;
    or 30 such tablets in a blister, one such blister in a cardboard box.
For Bisoprolol 10 mg there is an additional form of release:
    30 tablets in a blister, three such blisters in a cardboard package.

pharmachologic effect

Bisoprolol - a drug that has antiarrhythmic, antihypertensive, anti-anginal action.

Pharmacodynamics and pharmacokinetics


Medical preparation Bisoprolol is a selective beta-1-adrenoblocker, without sympathomimetic action. This medication also has no membrane-stabilizing effect.
The use of the drug Bisoprolol does not affect the state of the airways and metabolic processes in which beta-2-adrenergic receptors participate.
INN (international non-proprietary name) medications are bisoprolol.
Does not have a strong negative inotropic effect. Reduces the tone of the sympathoadrenal system, suppresses beta-1-adrenoreceptors of the heart.
With a single admission in patients with coronary heart disease without chronic heart failure, bisoprolol reduces the number of heartbeats, stroke volume of the heart, ejection fraction and the need for myocardium in oxygen. With long-term therapy, the increased total peripheral resistance of the vessels decreases.
The maximum effect occurs three hours after admission. When bisoprolol is prescribed once a day, its effect lasts 24 hours. The maximum pressure reduction is fixed 12-14 days after the start of therapy.
Bisoprolol is absorbed from the intestine by 90%. Bioavailability is 90%. Eating does not affect bioavailability. Concentrations of bisoprolol in the blood plasma are proportional to the accepted doses in the range of 5-20 mg. The greatest concentration in the blood occurs 3 hours.
Binding to plasma proteins is approaching 30%. All derivatives are excreted by the kidneys and are not pharmacologically active. The half-life is 11-12 hours.

Indications for the use of Bisoprolol

Indications for use:
    chronic heart failure;
    cardiac ischemia;
    arterial hypertension.


Before buy Bisoprolol, you should know contraindications to use of Bisoprolol:
    acute form of heart failure;
    decompensated chronic heart failure;
    AV-blockade of 2-3 degrees;
    cardiogenic shock;
    sinoatrial blockade;
    marked decrease in pressure;
    bronchial asthma and COPD;
    metabolic acidosis;
    severe changes in peripheral arterial blood circulation;
    age is less than 18 years;
    an allergy to the components of the drug.

Side effects of Bisoprolol

Reviews of side effects are not uncommon, most often reported on slowing of heart rate, hypotension, nausea and deterioration of well-being.
    On the part of the circulatory system: bradycardia, worsening of chronic heart failure, numbness of limbs, severe pressure decrease, orthostatic hypotension.
    From the nervous system and psyche: dizziness, loss of consciousness, headache, depression, insomnia, nightmares.
    On the part of the respiratory system: an attack of bronchial asthma.
    From the musculoskeletal system: convulsions, muscle weakness.
    From the sense organs: damage to the ear, conjunctivitis.
    On the part of the digestive system: diarrhea, nausea, vomiting, increase in the level of AST and ALT in the blood.
    From the genitourinary system: a violation of potency.
    From the skin: alopecia.
    Allergic reactions: itching, rash, skin redness, allergic rhinitis.

Instructions for use Bisoprolol (Method and dosage)

Instructions for Bisoprolol in tablets prescribe taking the drug orally, once a day, in the morning. Instructions for the use of the medicine also indicates that it should be washed down with a small amount of water without chewing.
With arterial hypertension and angina, the dose of the drug from the pressure of Bisoprolol is selected individually, taking into account the clinic's disease and the patient's condition. The initial dose is 5 mg once a day. If necessary, increase it by 5 mg once a day. In the treatment of arterial hypertension and angina, the maximum recommended dose is 20 mg per day.
In chronic course of heart failure, the usual therapy scheme involves the use of ACE inhibitors or angiotensin blockers, diuretics, beta-blockers and cardiac glycosides.
A prerequisite for therapy with the drug is a stable chronic course of heart failure without exacerbations. The maximum recommended dose for the treatment of this pathology is 10 mg once a day.
At the moment, there is insufficient data on the use of the drug in children, which is not recommended for children under 18 years of age.
Along with the question of how to take Bisoprolol, the most common question is how long can I take the drug? Abstract does not limit the duration of the drug. Authoritative Internet resources, for example, Wikipedia, also do not give clear instructions on this issue, reporting only that the course of treatment is long-term and determined by the attending physician.
There is insufficient data on the use of the drug in people with chronic heart failure complicated by type 1 diabetes, severe liver and kidney damage, or congenital heart defects with severe hemodynamic disorders, which Bisoprolol  in this category of patients should be administered with caution.


Overdose symptoms: bradycardia, severe depression of pressure, AV blockade, bronchospasm, hypoglycemia and acute heart failure.
Treatment: stop taking medication, start symptomatic therapy.
With bradycardia intravenous administration of atropine is indicated. With a strong reduction in pressure - intravenous injection of vasopressor preparations and plasma-substituting solutions.
With exacerbation of chronic heart failure - the introduction of diuretics and vasodilators.
With AV-blockade - the appointment of beta-adrenomimetics, if necessary - the installation of an artificial pacemaker.
When hypoglycemia - the introduction of glucose solution.
When bronhospazme recommended the appointment of aminophylline, β2-adrenomimetics.


Unrecommended combinations:

Antiarrhythmic drugs of the first class when combined with bisoprolol may reduce conduction and contractility of the heart.
Hypotensive drugs taken with bisoprolol can cause bradycardia, lower cardiac output and vasodilation.

Combinations that require caution

Class 3 antiarrhythmic agents (amiodarone) and parasympathomimetics increase the disturbance of AV conduction.
Local β-blockers activate systemic effects of bisoprolol.
The effect of hypoglycemic agents is enhanced when used with bisoprolol.
Cardiac glycosides when combined with bisoprolol lead to the development of bradycardia.
Nonsteroidal anti-inflammatory drugs reduce the hypotensive effect of bisoprolol.
The use of bisoprolol with nonselective adrenomimetics enhances vasoconstrictor effects of these agents, leading to an increase in pressure.
Mefloquine when used with bisoprolol may increase the possibility of developing a bradycardia.
MAO inhibitors increase the antihypertensive effect of beta-blockers.

Storage conditions

Keep away from children. Store at temperatures up to 30 ° C.
Shelf life - five years.

special instructions

It is not recommended to abruptly cancel the drug and change the recommended dosage without consulting a specialist, as this can cause a temporary deterioration of the heart.
Use with caution in the following cases:
    diabetes mellitus with symptoms of hypoglycemia;
    conducting desensitizing treatment;
    angina of Prinzmetal;
    strict diet;
    slight or moderate disturbance of peripheral blood circulation from the arteries;
    AV-blockade of the first degree;


The drug is not recommended for persons under 18 years of age.

With alcohol

Compatibility Bisoprolol and alcohol are a frequent topic of discussion of patients taking this drug. Alcohol is little compatible with any adrenoblockers because of the risk of orthostatic hypotension.

In pregnancy and lactation

The drug is not recommended for pregnancy and lactation, unless the expected positive effects from taking Bisoprolol will exceed the risk to the child. Reviews during pregnancy do not report complications.

Reviews of Bisoprolol

The doctors' comments on the tablets from Bisoprolol pressure generally fit into the average picture of reports about beta-blockers. The drug has its advantages and disadvantages.
Forums also contain enough estimates of the effectiveness of the medication. The most frequently asked question is: do the pressure of the Bisoprolol tablet decrease? It should also be remembered that the effectiveness is highly dependent on the individual characteristics of each individual patient.

Bisoprolol or Bisoprolol?

The answer to the question "Bisoprolol or Bisoprolol, which is better?" Is identical to the previous answer. These drugs are analogues, but bisoprolol has a lower price.

What is the difference between Bisoprolol Cor and Bisoprolol?

The most common question of the comparative effectiveness of drugs: how does Bisoprolol differ from Bisoprolol Cor? Both drugs contain bisoprolol as an active ingredient. The main difference between the drugs in the presence of tablets with a dosage of 2.5 mg in Bisoprolol Cor.

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