Venoruton caps 300mg #50

Venoruton user manual

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Composition

The preparation contains active substance rutozid.
Additional constituents: macrogol, gelatin, titanium dioxide, iron dye, yellow and black dioxide, shellac, n-butanol, propylene glycol, isopropanol and water.

Form of issue

It is produced by Venoruton in the form of gel, capsules, forte tablets and effervescent.
    Gel 2% is for external use and packaged in tubes of 40 and 100 g.
    Capsules are offered in a blister for 10 pieces, for 2 or 5 blisters in a pack.
    Forte tablets, with an active substance content of 500 mg, 10 pieces per blister, 3 blister packs.
    Tablets are effervescent, with an active ingredient content of 1 g of 15 pieces in a package of polypropylene, one in a pack.

pharmachologic effect

Venoruton is characterized by angioprotective action.

Pharmacodynamics and pharmacokinetics

This drug has a significant angioprotective and phlebotenic effect. Also, this medicine helps in correcting microcirculatory disorders that cause changes in the vascular and capillary walls. Thanks to this preparation, a tonic effect on the vascular walls is manifested, reducing the fragility of the capillaries. By reducing the pore size in the vascular walls, their permeability for the liquid and lipids normalizes.
Treatment with Venoruton helps restore the normal structure of the vascular endothelium and its function. As a result of inhibition of activation mechanisms and adhesion of neutrophils, the drug exhibits an anti-inflammatory effect. At the same rutosides, which are contained in the drug, inhibit the activity and release inflammatory mediators.
In addition, its antioxidant effect is noted, which is provided by certain mechanisms. Rutozidy can reduce the oxidative effect of oxygen, inhibit the peroxide oxidation of lipids, protect the tissues of blood vessels, preventing the influence of hypochlorous acid, as well as free radicals. Thanks to this preparation, the rheological characteristics of the blood are improved, which reduces the aggregation of erythrocytes and normalizes the degree of their deformability. This is the most important factor in the treatment of deep vein thrombosis and chronic venous insufficiency. The anti-edema, analgesic and anticonvulsant effect helps to normalize microcirculation, relieving patients of trophic disorders and varicose ulcers in chronic venous insufficiency. The drug helps to improve the overall condition of patients suffering from inflammation of the hemorrhoidal veins, reduce bleeding, itching and pain in hemorrhoids. Influencing capillary walls and rheological blood quality, the occurrence of microthrombi is prevented and the risk of developing various deviations in vascular etiology is reduced.
Taking the drug orally helps improve the condition of patients who suffer from diabetes mellitus, slowing the development of diabetic retinopathy.
When the drug is used externally, it penetrates the epidermis, reaching the dermis and subcutaneous tissue, but its presence in the blood is not determined. Achieving the maximum level of concentration in the dermis is achieved after 0.5-1 hour from the time of application and approximately 2-3 h in the subcutaneous tissue.
Getting inside the body, the drug is subjected to a low absorption from the gastrointestinal tract, which is approximately 10-15%. Achieving the maximum concentration in the blood plasma occurs within 4-5 hours, even after taking the drug in a single dose. The half-life is 10-25 hours. Metabolism is realized with the production of glucuronized substances. Removal of the drug from the body occurs with bile, feces and urine in the unchanged form and metabolites.

Indications for use

Venoruton gel is recommended for external use when:
    pain syndromes and swelling caused by various injuries;
    painful sensations caused by sclerosing therapy;
    complex therapy of chronic venous insufficiency, varicose veins, for example, pain in the legs, severe fatigue, heaviness of the legs, swelling of the lower limbs.
Tablets and capsules are prescribed for:
    chronic venous insufficiency;
    post-phlebitic syndrome;
    Varicose dermatitis, ulcers and other conditions caused by disturbances of trophic and microcirculation;
    complex therapy of patients, after sclerosing treatment or removal of varicose veins;
    hemorrhoids with severe symptoms - pain, itching, rectal bleeding and so on.

Contraindications

It is not recommended to apply the drug when:
    high sensitivity to its components;
    the initial period of pregnancy, namely in the first 3 months.

Side effects

This drug is usually tolerated by patients well, but it is possible to develop unwanted effects in the form of: nausea, vomiting, stool, heartburn, abdominal pain. In rare cases, headaches or hyperemia occur in the upper part of the body.
External application of the drug may be accompanied by local allergic reactions, for example, pruritus and urticaria.

Instructions for the use of Venoruton (Method and dosage)

Capsules and tablets Venoruton instruction for use recommends use only as directed by the doctor, given the severity of the disease and the individual characteristics of the patient.
For example, for the treatment of chronic venous insufficiency, varicose veins, hemorrhoids, adult patients are prescribed a drug in an initial dosage of 300 mg to 3 times or 500 mg to 2 times a day. It is possible to take medication in a single daily dosage of 1g.
It is recommended that you take capsules or tablets while eating. Treatment should be carried out until the symptoms of the disease completely disappear, after which the therapy is stopped until another resumption of symptoms. On average, the effect of treatment persists for 4 weeks. In cases of manifestations of undesirable symptoms, it is possible to take maintenance daily doses - 600 mg per day.
Venoruton gel instructions for use recommends external application not more than 2 times a day. In this case, the ointment is applied in the required quantity with a sufficiently thin layer, and then rubed until it is completely absorbed. Also, this external agent is actively used for applying under elastic bandages or special stockings. When undesirable symptoms disappear, a maintenance dosage can be used that is applied only once a day, preferably overnight.

Overdose

Cases of overdose by any form of the drug is not established.

Interaction

Strengthen the effect of this drug can its simultaneous use with agents that contain ascorbic acid.

Terms of sale

To buy Venoruton you don't need a prescription.

Storage conditions

To store this drug is suitable for dry, cool place, not accessible to children.
Shelf life - 4 years.

Reviews about Venoruton

Discussions of this drug are quite common. Often reviews about Venoruton in tablets confirm the effectiveness of the drug. In this case, patients, who are concerned about different types of lymphovenous insufficiency, report a noticeable improvement in their well-being.
Often, users describe the effectiveness of the external means. To a large extent, the reviews about Venoruton gel are related to the normalization of venous disorders on the legs. Also, there were cases of reducing symptoms of exacerbation of hemorrhoids, which under the action of this drug occurred much faster.
The effect of the drug is fairly active in pregnant women. In this condition, the drug can be prescribed for the treatment of fetoplacental insufficiency, as well as in cases of violations of venous outflow, when the fetus presses on the vessels. In this case, the capsule or other form of the drug should be canceled a few weeks before the expected delivery period.
As for the specialists, they prescribe this medicine to their patients. Doctors believe that it helps well in the treatment of venous insufficiency, but especially with hemorrhoids.
It should be noted that Venoruton is one of the most effective venotonics. Nevertheless, even its use requires additional measures, for example, wearing compression linen, changing diet, lifestyle, using other procedures and medicines that can have a beneficial effect on the health of lymphatic vessels and veins.
Only with this approach can we hope for a good therapeutic effect.