Troxerutin caps 300mg #100

Troxerutin user manual

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Composition

The composition of troxerutin, in the form of capsules, includes 300 mg of troxerutin and excipients: lactose monohydrate (Lactose monohydrate), silicon dioxide colloid (Silicon dioxide colloidal), macrogol 6000 (Macrogol 6000), magnesium stearate .
To make the capsule used: titanium dioxide (Titanium dioxide), gelatin (Gelatin), dyes (quinoline yellow - 0,75%, sunset yellow - 0,0059%).
Gel composition: Troxerutin at a concentration of 20 mg / g, methyl parahydroxybenzoate (E218; Methyl parahydroxybenzoate), carbomer (Carbomer), triethanolamine (Triethanolamine), disodium edetate (Edetate disodium), purified water (Aqua purificata).

Form of issue

The medicine is issued in the form:
    gel for external use in tubes of aluminum with a volume of 25, 35, 40, 50 and 100 grams;
    capsules, packaged in 10 pieces in blisters, 5 blisters each in one carton.

pharmachologic effect

The drug refers to the pharmacological group of drugs that have antispasmodic effect, help to relax the smooth muscles of blood vessels and other internal organs.

Pharmacodynamics and pharmacokinetics

The drug increases the tone of the walls of venous vessels and reduces their extensibility, thereby eliminating the stagnation of venous blood and preventing the development of edema, reduces the intensity of the inflammatory process, has a membrane-stabilizing and capillaroprotective effects.
Troxerutin takes an active part in oxidation-reduction processes, inhibiting the processes of lipid peroxidation and hyaluronidase, as well as the processes of oxidation of epinephrine (adrenaline) and ascorbic acid.
The drug is characterized by P-vitamin activity, it stimulates the processes of elimination of metabolic products from tissues, has no embryotoxic effect, does not cause mutations and fetal development disorders.
After oral administration, it is well absorbed from the digestive tract. Plasma concentration of the substance reaches its peak values ​​2-8 hours after taking the capsule. The second peak is observed after about 30 hours.
Troxerutin is almost completely eliminated from the body within 24 hours after ingestion, with about 75-80% of the substance excreted by the liver, the remaining 20-25% by the kidneys.
With local application of absorption of the substance into the systemic blood stream does not occur, however, the drug penetrates well into the adjacent tissues through the skin.

Indications for use: what is prescribed by Troxerutin

The use of tablets and gel Troxerutin is advisable:
    with accompanying trophic skin lesions, static weight in the legs, ulcers of the lower leg, chronic venous insufficiency;
    with varicose veins (including during pregnancy);
    with postthrombophlebitic syndrome;
    with peri- and thrombophlebitis;
    with hemorrhoids;
    with hemorrhagic diathesis, which are characterized by increased permeability of capillary walls;
    with post-traumatic hematomas and swelling of tissues;
    with Shenlaine-Henoch disease (hemorrhagic capillarotoxicosis, including influenza, measles or scarlet fever);
    with diabetic retino- and microangiopathy;
    with vascular effects, developed on the background of radiation therapy.
As a preventive remedy, the drug can be used after vein surgeries.

Contraindications

Contraindications for use are:
    hypersensitivity to the components of the drug;
    chronic gastritis in the phase of exacerbation;
    stomach ulcer;
    duodenal ulcer;
    age up to 15 years;
    the first trimester of pregnancy;
    breast-feeding.
Caution is prescribed with insufficient kidney function (if necessary for prolonged use).

Side effects

The use of the drug may be accompanied by the following side effects:
    headache;
    irritation of the mucous organs of the digestive tract;
    allergic reactions, which are expressed in the form of rashes on the skin and skin itching.

Instructions for use Troxerutin

Capsules Troxerutin: instructions for use

Tablets Troxerutin is taken with food, swallowing whole. In accordance with the standard treatment schedule, intake of 0.9 grams of troxerutin per day is prescribed (one tablet three times a day). If the medicine is used as a supporting agent, it should be taken one capsule twice a day.
The full course of treatment lasts from 3 to 4 weeks. The advisability of a longer-term use is determined individually by the attending physician.
Instructions on preparations of different manufacturers may differ somewhat among themselves.
So, for example, the capsules of Troxerutin Zentiva are taken as described above, and the capsules of Troxerutin Vramed are taken at the initial stages of treatment one or two times a day and then switch to maintenance treatment, which involves taking one capsule per day.
Treatment with the use of Troxerutin-MIC begin with intravenous or intramuscular injection of 0.5 grams of troxerutin in the form of an injection solution. The procedures are repeated every other day, and at least 5 injections are recommended.
After this, they switch to taking oral dosage forms. The starting dose is 0.6-0.9 grams per day, the maintenance dose is 0.3 grams per day. The course of treatment is from 2 to 4 weeks, if there is no other indication.

Gel Troxerutin: instructions for use

Ointment Troxerutin is a remedy for external use. Apply it twice a day (in the morning and evening hours), a thin layer, evenly distributing the skin of the painful area from the distal (the most remote) to the proximal (closest) part of it and lightly massaging until completely absorbed.
The dose is determined by the area of ​​the damaged surface, but it should not exceed 1-2 grams (this corresponds to approximately 3-4 cm of the gel). After applying the medicine to the affected area of ​​the skin, you can impose an occlusive dressing.
Unlike capsules, the treatment scheme with the use of gels of different manufacturers is no different, that is, the instruction for using the ointment Troxerutin Vramed is identical to the instructions, for example, Troxerutin Vetprom.

Overdose

To date, there have been no reports of cases of an overdose of Troxerutin.
In case of accidental ingestion of the drug in the form of a gel or capsules in a dose significantly higher than the therapeutic one, a procedure for washing the stomach should be performed and the enterosorbent taken.
There is no specific antidote.

Interaction

The drug potentiates the action of ascorbic acid on the structure and indices of the permeability of the walls of blood vessels.

Terms of sale

You can buy Troxerutin without a prescription.

Storage conditions

Store in a place protected from sunlight from the sun. The optimum temperature regime for storing the gel is 8-15 ° C, for capsules - 15-25 ° C.

Shelf life

Gel is usable for 2 years, capsules within 5 years from the date of release.

special instructions

Gel and capsules Troxerutin is allowed to be used as one of the components of complex therapy. Thus, therapy for deep vein thrombosis or superficial thrombophlebitis does not exclude the need for antithrombotic and anti-inflammatory drugs.
The experience of using the drug to treat patients younger than 15 years is absent.

Troxerutin in Pregnancy

In pregnancy, Troxerutin is allowed to be used from the second trimester, in the first 13 weeks it is not recommended to use it.
During the period of breastfeeding, the drug can be prescribed if the expected benefit to the mother exceeds, by preliminary assessment, the potential risks to the child.

Reviews about Troxerutin

Find negative reviews about the gel Troxerutin is difficult. At its low price (the medicine is a 100% analogue of a much more expensive drug, Troxevasin), the drug is described as very effective.
However, as most patients rightly point out, to achieve maximum effect, it is better to use it in the early stages of the disease.
To the question "Troxerutin - what is it?" Most people with early manifestations of varicose veins respond that the ointment for them is a real salvation from the spider veins, fatigue and soreness of the legs, and also from bruises and cones.
One of the indications for the use of the drug is the presence of hemorrhoids (a common problem that pregnant women and newly-born women often encounter).
When hemorrhoids treatment involves the use of troxerutin in the form of compresses, and many remain satisfied with the result. Although, objectively for the sake of, it should be said that this method does not help everyone (here, probably, it all depends on the severity of the pathology).
Analyzing the patients' feedback on capsules of troxerutin and gel for external use, it can be concluded that both dosage forms are often powerless in severe lesions: they do not help to remove large nodes in venous vessels, but probably prevent the process from worsening.
As for the doctors' feedback on tablets and ointments, almost all specialists note the need for their application in the complex. In more neglected situations, therapy is begun with the administration of troxerutin preparations in the form of a solution for injection.
The key to successful treatment, according to doctors, is the regularity and timeliness of the drug. And it is optimal to start using the remedy already when the first signs of the development of the pathological process appear.
Patients also note that the most pronounced result was achieved in cases when the use of the drug was supplemented by swimming, dousing with cold water, using essential oils (eg cypress oil), Ascorutinum.
It should be remembered that the composition is not suitable for removing the swelling of the legs, which is associated with kidney dysfunction, liver and heart diseases. Before using the drug and the use of concomitant medical measures should always consult with your doctor.