Acyclovir ointment 5% 5gr
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Acyclovir ointment instructionYou can buy Acyclovir ointment hereComposition100 g of ointment contains:active substance: acyclovir in terms of 100% substance - 5 g;auxiliary substances: propylene glycol 40 g, petroleum jelly 12,5 ..
Acyclovir ointment instruction
You can buy Acyclovir ointment here
100 g of ointment contains:
active substance: acyclovir in terms of 100% substance - 5 g;
auxiliary substances: propylene glycol 40 g, petroleum jelly 12,5 g, vaseline oil 7,5 g, emulsion wax 5 g, macrogol (polyethylene oxide 1500) -1 g, purified water up to 100 g.
ointment is white or almost white. A characteristic odor is allowed.
antiviral agent for topical use
Pharmacological properties of Acyclovir ointment
The antiviral drug is a synthetic analogue of thymidine nucleoside.
In infected cells containing viral thymidine kinase, phosphorylation and conversion to acycpovir monophosphate occurs. Under the influence of guanylyl cyclase acyclpovir monophosphate is converted into diphosphate and under the influence of several cellular enzymes - in triphosphate.
High selectivity of action and low toxicity for humans are due to the lack of the necessary enzyme for the formation of acyclpovir triphosphate in intact cells of the macroorganism.
Acyclovir triphosphate, "embedded" in the DNA synthesized by the virus, blocks the multiplication of the virus. Specificity and very high selectivity of action are also due to its predominant accumulation in cells affected by the herpes virus. Highly active against Herpes simplex virus type 1 and type 2; a virus that causes varicella and herpes zoster (Varicella zoster); the Epstein-Barr virus. Moderately active against cytomegalovirus.
When used on intact skin: suction is minimal; not detected in blood and urine. On the affected skin: moderate absorption; in patients with normal renal function, the serum concentration in the serum is up to 0.28 μg / ml, in patients with chronic renal insufficiency (CRF), up to 0.78 μg / ml. It is excreted by the kidneys (up to 9.4% of the daily dose).
Indications for use
Skin infections caused by the Herpes simplex virus types 1 and 2, genital herpes, shingles, chicken pox.
Hypersensitivity to acyclovir and other components of Acyclovir ointment.
With caution - pregnancy, lactation, dehydration, kidney failure.
Pregnancy and lactation
The use of Acyclovir ointment is indicated only in cases where the intended use for the mother exceeds the potential risk to the fetus. During the treatment period, it is necessary to resolve the issue of stopping breastfeeding.
Dosing and Administration
Outwardly. Acyclovir ointment is applied with clean hands or a cotton swab 5 times a day (every 4 hours) with a thin layer on the affected and adjacent areas of the skin.
Therapy should be continued until the time when no bubbles form on the vesicles, or until they completely heal. The duration of therapy is an average of 5 days, a maximum of 10 days. If there is no effect, consult a doctor.
Hyperemia, dryness, scaling of the skin; burning, inflammation in contact with mucous membranes. Possible the development of allergic dermatitis.
Interaction Acyclovir ointment with other drugs
With external application, no interaction with other drugs has been identified. An increase in the effect is noted with the simultaneous appointment of immunostimulants.
To achieve maximum therapeutic effect, it is necessary to apply Acyclovir ointment as early as possible (at the first signs of the disease: burning, itching, tingling, sensation of tension and redness).
Ointment is not recommended to be applied to the mucous membranes of the mouth and eyes, as it is possible to develop a pronounced local inflammation.
In the treatment of genital herpes, sexual intercourse or condom use should be avoided, since the use of acyclovir does not prevent the transmission of the virus to partners.
Form of issue
Ointment for external use 5%.
By 2, 3 or 5 g in an aluminum tube. Each tube together with the instruction for use is placed in a pack of cardboard.
In a dry, the dark place at a temperature of no higher than 25 ° C.
Keep out of the reach of children.
Shelf life - 3 years. Do not use Acyclovir ointment after the expiration date.
Conditions of leave from pharmacies
You don't need a prescription to buy Acyclovir ointment.