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Nurofen express gel 5% 100gr

  • $17.25
  • 3 or more $16.90
  • Availability:In Stock

Nurofen express gel instruction for useYou can buy Nurofen express gel on this pageClinical and pharmacological groupNSAIDs for external useForm of release, composition and packagingThe gel for external use is transparent or sligh..

Tags: gel

Nurofen express gel instruction for use

You can buy Nurofen express gel on this page

Clinical and pharmacological group

NSAIDs for external use

Form of release, composition and packaging

The gel for external use is transparent or slightly opalescent, colorless, uniform, with a characteristic smell of isopropyl alcohol.

pharmachologic effect

NSAIDs for external use. Has a double action: analgesic and anti-inflammatory.
Ibuprofen, being a derivative of propionic acid, indiscriminately blocks COX-1 and COX-2, which inhibits the synthesis of prostaglandins - mediators of pain, inflammation and hyperthermia.
The gel is easy to apply and quickly absorbed into the skin. When applied to the skin, the gel has an additional cooling effect due to the rapid evaporation of the benzyl alcohol contained in the formulation.


After application to the skin, ibuprofen is found in the epidermis and dermis after 24 hours. Cmax in the blood plasma of ibuprofen when applied topically makes up 5% of the Cmax level when ibuprofen is administered orally. Clinically significant systemic absorption hardly occurs.
It is metabolized in the liver. It is excreted by the kidneys (in unchanged form - no more than 1%) and, to a lesser extent, with bile.


As a local analgesic and anti-inflammatory agent under the following conditions:
- myalgia;
- back pain;
- arthritis;
- damage to ligaments, sprains;
- sports injuries;
- Neuralgia.


- the presence in the history of hypersensitivity reactions (bronchial asthma, rhinitis, urticaria, Quincke's edema), provoked by the intake of acetylsalicylic acid or other NSAIDs;
- violation of the integrity of the skin at the site of application (including infected abrasions and wounds, wet dermatitis, eczema);
- Children and adolescence up to 14 years;
- III trimester of pregnancy;
- Hypersensitivity to the components of the drug or to other NSAIDs.
With caution apply the drug with bronchial asthma or allergic diseases in the stage of exacerbation or in the anamnesis (possibly the development of bronchospasm), kidney failure, liver failure, gastric ulcer (including in the history), enteritis, colitis, hemorrhagic diathesis, in I and II trimesters of pregnancy, the period of breastfeeding.


The drug is intended for external use.
Gel is prescribed for adults and children over 14 years of age.
When using the tube for the first time, it is necessary to open the lid and make sure that the safety foil on the tube neck is not damaged. Open the foil by pressing it against the outside of the cover.
Squeeze 4-10 cm of the drug from the tube (equivalent to approximately 50-125 mg of ibuprofen) and gently rub the gel into the skin until it is completely absorbed.
Immediately after using the product, you should wash your hands.
Reapply the gel should not be earlier than 4 hours. Do not use the drug more than 4 times / day. The maximum daily dose is 500 mg. Do not exceed the indicated dose.
If the symptoms persist or worsen during the 2 weeks of the drug, stop treatment and consult a doctor.

Side effects

The incidence of adverse reactions is estimated on the basis of the following criteria: very often (≥1 / 10), often (from ≥1 / 100 to <1/10), infrequently (from ≥1 / 1000 to <1/100), rarely from ≥1 / 10,000 to <1/1000), very rarely (> 1/10 000), the frequency is unknown (the frequency can not be determined from the available data).
The following adverse reactions were noted with a short-term use of ibuprofen in a dose not exceeding 500 mg / day. In the treatment of chronic conditions and with prolonged use, other side reactions may occur.
From the side of the immune system: the frequency is unknown - hypersensitivity reactions (nonspecific allergic reactions and anaphylactic reactions), reactions from the respiratory tract (bronchial asthma, including its aggravation, bronchospasm, dyspnea, dyspnea), skin reactions (itching, urticaria, purpura, Quincke's edema, exfoliative and bullous dermatoses, including toxic epidermal necrolysis (Lyell's syndrome), Stevens-Johnson syndrome, erythema multiforme).
On the part of the digestive system: the frequency is unknown - abdominal pain, dyspepsia.
From the side of the urinary system: the frequency is unknown - a violation of kidney function.
If side effects occur, discontinue use immediately and consult a doctor.


The likelihood of an accidental drug overdose in the form of a gel is minimal. In children, the symptoms of overdose may occur after ingestion at a dose exceeding 400 mg / kg body weight. In adults, the dose-dependent effect of an overdose is less pronounced. T1 / 2 of the drug with an overdose of 1.5-3 hours.
Symptoms: if the drug was accidentally ingested, headache, vomiting, and lowering blood pressure may occur.
Treatment: gastric lavage (only within an hour after administration), reception of activated charcoal, alkaline drink, forced diuresis, symptomatic therapy.

Drug Interactions

With caution should be used at the same time with the following drugs: anticoagulants and thrombolytic drugs, antihypertensive drugs, acetylsalicylic acid, other NSAIDs.
It should be borne in mind that even with topical application of ibuprofen, its systemic effect can not completely be excluded and, theoretically, with simultaneous application of the Nurofen Express gel with other NSAIDs, side effects may increase.

special instructions

Avoid contact with the eyes, lips and other mucous membranes, damaged skin.
Do not use Nurofen Express gel in combination with an occlusive (airtight) medical dressing.
Avoid exposure to sunlight on the area of ​​application.
Impact on the ability to drive vehicles and manage mechanisms
The drug does not affect activities requiring increased concentration of attention and speed of psychomotor reactions (driving vehicles or controlling mechanisms).

Pregnancy and lactemia

Contraindicated use of the drug in the III trimester of pregnancy. Avoid the use of the drug in the I and II trimesters of pregnancy, if necessary, use the drug should consult a doctor.
There is evidence that ibuprofen in small amounts can penetrate into breast milk without any negative consequences for the health of the infant, therefore, for short-term use, the need to stop breastfeeding usually does not arise.
If it is necessary to take the drug for a long time, you should consult a doctor to resolve the issue of stopping breastfeeding for the period of drug use.

Application in childhood

The drug is contraindicated in children under 14 years of age.

In case of violations of kidney function

With caution apply the drug for kidney failure.

With violations of liver function

With caution apply the drug in case of liver failure.

Conditions of leave from pharmacies

The drug is approved for use as a means of OTC.

Terms and conditions of storage

The drug should be stored out of the reach of children at a temperature of no higher than 25 ° C. Shelf life - 3 years.

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