Tisalud tabs 2mg #30

Tisalud instruction

Reed more and buy Tisalud online

Composition

One tablet contains: 2 mg or 4 mg Tizanidine is the active ingredient.
Additional substances: sodium carboxymethyl starch, lactose anhydrous, magnesium stearate, microcrystalline cellulose.

Form of issue

The drug Tisalud is available in the form of tablets of 2 and 4 mg, 30 pieces in one package.

pharmachologic effect

Miorelaxing, central action.

Pharmacodynamics and pharmacokinetics

Tisalud is a muscle relaxant showing a central effect.
The effect of tizanidine on presynaptic α2-adrenergic receptors causes inhibition of the excretion of amino acids from spinal intermediate neurons, which leads to inhibition of the polysynaptic spread of the pulse in the spinal cord. By this mechanism of action, muscle tissue tone is lowered. In parallel with the miorelaksiruyuschim effect tizanidine shows a moderate analgesic effect.
Tisalud tablets are effective in acute painful muscle spasms, as well as chronic spasms of cerebral and spinal etiology. Taking the drug reduces clonic seizures and spasticity of the muscles, as a result of which the counteraction to passive movements decreases and the possibility of active actions increases.

Indications for use

Muscle spasms in pathologies of the spine, accompanied by pain syndrome, including hemiplegia, spondylosis, osteochondrosis, syringomyelia, lumbar and cervical syndromes.
Postoperative period after surgical intervention for osteoarthritis of the femoral joint and intervertebral hernia.
Pain syndrome and spasticity of muscles caused by neurological diseases, including chronic myelopathy, multiple sclerosis, cerebral palsy, degenerative changes in the spinal cord, stroke, circulatory disorders of the brain, craniocerebral trauma, convulsions of the central genesis.

Contraindications

    hypersensitivity to tizanidine or other constituent ingredients of Tisalud tablets;
    severe liver diseases;
    periods of breastfeeding and pregnancy;
    age up to 18 years;
    parallel therapy with the administration of ciprofloxacin, fluvoxamine and other strong inhibitors of the isoenzyme CYP1A2.

Carefully:

    age over 65 years;
    kidney failure;
    bradycardia;
    arterial hypotension;
    use of oral contraceptives.

Side effects

CNS:

    dizziness;
    drowsiness;
    hallucinations;
    sleep disorders;
    insomnia.

The cardiovascular system:

    lowering blood pressure;
    bradycardia.

Digestive system:

    dryness in the oral cavity;
    dyspepsia;
    nausea;
    hepatitis;
    increased activity of "liver" transaminases;
    liver failure.

Musculoskeletal system:

    muscle weakness.

Others:

    hypercreatininaemia;
    increased fatigue.
A sharp abolition of Tisalud after combined use with antihypertensive drugs and prolonged therapy and / or use of large doses may lead to an increase in blood pressure, tachycardia, and in some cases to severe impairment of the blood circulation of the brain.

Tablets Tisalud, instructions for use

Tablets of the drug are taken orally (by mouth), washed down with water, regardless of food.
Instructions for the use of Tisalud in neurological pathologies that cause spastic painful muscle contraction, recommends starting treatment with a daily dose of 6 mg, taken in three divided doses. Every subsequent 3-7 days, depending on the nature of the pain and spasm, increase the dose by 2-4 mg. The maximum therapeutic effect is observed when taking a daily dose of 12-24 mg. The dose of 36 mg is the maximum allowable daily dose.
To stop painful spasm of skeletal muscles, 3-day daily administration of Tisalud is prescribed for 2-4 mg. In especially difficult situations, an additional intake of 2-4 mg per night is recommended.
The duration of Tisalud depends on the dynamics of pain and muscle-tonic manifestations. Acute muscle pain usually requires therapy for 7-21 days. Chronic pain syndrome, depending on the origin and severity, may need a longer treatment, which is determined on an individual basis and sometimes continues for up to 1 year.

Overdose

With a gross violation of the dosage regimen and the administration of elevated doses of Tisalud, nausea, vomiting, development of hypotension, drowsiness, dizziness, miosis, respiratory disturbance, anxiety, coma were observed.
Recommend immediate gastric lavage, cleaning the bowels with enema, taking activated charcoal, conducting forced diuresis and further symptomatic therapy.

Interaction

It is not allowed to simultaneously take Tisalud with Ciprofloxacin, Fluvoxamine and other strong inhibitors of the CYP1A2 isoenzyme, including Amiodarone, Propaphenone, Mexiletin, Cimetidine, Enoxacin, Norfloxacin, Pefloxacin, Rofecoxib, Ticlopidine and oral contraceptives.
Antihypertensive drugs increase the risk of bradycardia and lowering blood pressure.
Sedation drugs and ethanol can enhance the sedative effects of tizanidine.

Storage conditions

The preparation of Tisalud is stored in a dark dry place, at ambient temperatures up to 25 ° C.
Shelf life - 24 months.

special instructions

When carrying out long-term treatment with Tisalud, the liver should be monitored at least once a month, especially during the first 4 months of therapy.
Because of the threat of the development of the "withdrawal syndrome", with the refusal of therapy, the dose of tizanidine is gradually reduced.
When taking pills, it is better to give up driving and carrying out accurate or dangerous work.

Children

Tisalud is not assigned until the age of 18 years.

With alcohol

Joint reception of Tisalud and alcohol is not recommended.

During pregnancy (and lactation)

Contraindicated use of tablets Tisalud during periods of breastfeeding and pregnancy.

Reviews of Tisalud

On user forums there are both positive and negative reviews about Tisalud. What is characteristic, negative reviews most often refer to the side effects of the drug that occur immediately after the first dose, and manifested by lowering blood pressure, weakness, dizziness, inhibition and drowsiness. Such effects are possible when taking the drug in large doses or whether the patient has any contraindications. Therefore, even if you completely trust your doctor, it is better to start therapy with taking half or even a quarter of the recommended dose and with normal drug tolerance to switch to full use.
A lot of patients are satisfied with the effectiveness of Tisalud, note its rapid action and the absence of side effects. Of course, any medicine is individual for each individual patient and if Tisalud did not cause you negative reactions, then most likely it will become a truly effective remedy.