Viagra for men 100mg #1

Viagra instruction manual

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Viagra tablets are a pharmacological group of drugs used to treat erectile dysfunction in men. The drug does not affect erectile dysfunction of mental central origin.

Form of issue and composition

The drug Viagra is available in the form of coated tablets. One tablet contains the main active substance sildenafil (in the form of citrate) in several dosages - 25, Viagra 50mg and 100 mg. Also, the tablet contains auxiliary components:
    Magnesium stearate.
    Microcrystalline cellulose.
    Calcium hydrophosphate is anhydrous.
    Croscarmellose sodium.
Tablets are packaged in blisters for 1, 2, 4 and 12 pieces. A cardboard pack contains one blister with an appropriate number of tablets and instructions for the use of the drug.

pharmachologic effect

The main active substance of Viagra tablets has on the development of erection in men during the onset of sexual arousal, by increasing the flow of blood to the cavernous bodies of the penis. Sildenafil inhibits the enzyme cAMP-specific phosphodiesterase type 5 (PDE5). This leads to an increase in the concentration of cAMP (cyclic adenosine monophosphate), which causes relaxation of the smooth muscles of the walls of the blood vessels and cavernous bodies of the penis and strengthens their filling with blood, leading to an erection. Also, local excitation produces nitric oxide (NO), which stimulates an increase in the concentration of cAMP. It is believed that the active substance of Viagra tablets enhances the action of nitric oxide. The main condition for the effect of using this drug is the presence of sexual stimulation of a man and his arousal.
After ingestion of Viagra pills, sildenafil is quickly absorbed from the lumen of the small intestine into the bloodstream. Its therapeutic concentration is achieved already half an hour after taking the pill, the maximum concentration - after 1 hour. When taking the tablet inside after eating, the suction rate is slightly lower than that on an empty stomach. Sildenafil is evenly distributed in all tissues. Its metabolism occurs to hepatocytes (liver cells) with the formation of intermediate decay products, which are excreted from the body with feces (up to 90%). Half-life (the time during which half of the entire dose is excreted from the body) is 4 hours.

Indications for use

The main indication for the use of Viagra tablets is the correction of sexual erectile dysfunction in men, until the erection of the penis is sufficient to perform sexual intercourse. An important condition for achieving the result is the presence of a man's sexual arousal.

Contraindications for use

The use of Viagra tablets is contraindicated in certain pathological conditions of the body, which include:
    Individual intolerance or hypersensitivity to sildenafil or ancillary components of the drug.
    The simultaneous use of Viagra tablets and other drugs that are donors of nitric oxide, which can potentiate the hypotensive effect and lead to a significant reduction in systemic blood pressure.
    The state of the body of men, in which unwanted sexual activity - severe cardiovascular pathology, ischemic heart disease, stable or unstable angina, the presence of acute or chronic heart failure.
    Loss of sight per eye due to non-ischemic neuropathy of the optic nerve, regardless of the association of this pathology with previous use of drugs or compounds that are inhibitors of the PDE5 enzyme.
    the presence of diseases of the cardiovascular system, which are accompanied by a decrease in systemic arterial pressure (arterial hypotension).
    Concomitant liver or kidney failure.
    Hereditary degenerative pathology of the retina.
    Recently suffered myocardial infarction or stroke of the brain.
The presence of contraindications must be determined before the application begins.

Dosing and Administration

Viagra tablets are taken orally regardless of food intake (fasting bioavailability and the rate of absorption of the active substance of the drug from the intestine above). The tablet should be taken immediately after removal from the blister, since its prolonged exposure to air can reduce the concentration and activity of sildenafil. Also during the reception it is recommended to hold the tablet for a while in the oral cavity before softening it, and then swallow it, for better passage of the tablet through the esophagus it can be washed down with a small amount of liquid. The recommended dose is 50 mg, if necessary, it can be increased to 100 mg. The maximum daily dose is 100 mg per dose. To achieve a quality effect, a tablet of Viagra should be taken 1 hour before the alleged sexual activity. In the case of liver failure, the dose of the drug taken is reduced to 25 mg.

Side effects

After taking Viagra tablets, side effects may occur, the frequency of which depends on the dosage. Such negative reactions can develop on the part of various organs and systems, they include:
    The digestive system - nausea, vomiting, abdominal pain, unstable stool.
    The central nervous system - dizziness, insomnia, increased muscle tone.
    Respiratory system organs - nasal congestion, laryngitis (inflammation of the larynx), pharyngitis (inflammatory reaction of the pharyngeal mucosa), impaired function of external respiration.
    Urinary system - the development of infectious inflammation of the urinary tract (urethritis, cystitis).
    Organs of the senses - impaired vision in the form of fog before the eyes, a change in color perception, conjunctivitis.
    Musculoskeletal system - pain in the muscles and joints.
    The sexual system is a violation of the functional activity of the prostate gland, a prolonged erection, which can last up to an hour (priapism).
    Allergic reactions - develop quite rarely, manifest as a rash on the skin, itching or hives (a rash in the form of blisters, reminiscent of a nettle burn).
In case of side effects, the drug should be discontinued and seek medical attention.

special instructions

Before starting the use of Viagra tablets, you should carefully read the instructions, there are several specific instructions for taking this medication:
Viagra tablets should be used with caution in men who have anatomical defects of the penis, which can manifestly manifest with his erection (Peyronie's disease, angulation, connective tissue fibrosis of cavernous bodies).
    It is not recommended to use the drug for persons with predisposition to priapism (prolonged erection) against the background of sickle cell anemia, leukemia, multiple myeloma.
    For a good result after taking the drug, you need sexual stimulation.
    The use of Viagra tablets for men, which is contraindicated in sexual activity, is excluded, especially due to the pathology of the cardiovascular system.
    The drug is not indicated for use in women.
    Do not take Viagra pills for children and adolescents under 18 years.
    You can not use the drug during work, requiring increased concentration or speed of psychomotor reactions.
In the pharmacy network, Viagra tablets are dispensed without a prescription. In case of questions or doubts about the use of the drug, you should consult a doctor.

Overdose

If the recommended therapeutic dose of Viagra tablets is exceeded, the symptoms of side effects from various organs and systems develop. The higher the degree of overdose, the more pronounced its symptomatology. In such cases, gastric, intestinal and symptomatic washing is performed.

Viagra analogues

Analogues of Viagra tablets according to the active substance are verona and impaza.

Terms and conditions of storage

The shelf life of Viagra tablets from the moment of manufacture is 5 years. The drug should be stored in a dry, dark place inaccessible to children at an air temperature not exceeding + 25 ° C.