Sumatriptan 100mg #2

Sumatriptan user manual

You can buy Sumatriptan online

Composition

One tablet of sumatriptan contains 140 mg. active drug sumatriptan succinate.
In addition, the preparation contains such auxiliary compounds as: mannitol, calcium hydrogen phosphate dihydrate, giprolase, magnesium stearate, microcrystalline cellulose, and croscarmellose sodium.
The composition of the tablet shell includes the macrologist, the selekut AQ-02003, as well as titanium dioxide.

Form of issue

Sumatriptan is produced in the form of tablets coated with a special film membrane. In one cardboard package, as a rule, contains one blister with two tablets.

pharmachologic effect

The drug refers to the serotonergic group of drugs that have an anti-migraine effect.

Pharmacodynamics and pharmacokinetics

The active drug sumatriptan, contained in the chemical composition of the drug, refers to specific selective agonists of 5-HT1-serotonin receptors, concentrated primarily in the vessels of the brain. The drug acts on some subtypes of serotonin receptors, for example, 5-HT 2-7, and thus contributes to the narrowing of the vessels of the arterial bed, the expansion of which leads to edema and causes migraines.
It should be noted that sumatriptan does not have any significant effect on the blood flow in the brain and at the same time it suppresses the excessive activity of the trigeminal nerve receptors, which leads to a decrease in the release of sensory neuropeptides. The drug quickly removes migraine symptoms such as bouts of nausea, as well as photophobia.
The drug can effectively suppress migraine attacks already with a single application in a dose of up to 100 mg. Sumatriptan begins to act after a maximum of half an hour from the time it is ingested.

Indications for use

The drug compound is recommended for use in migraines for relief of acute attacks of the disease and further stabilization of the condition.

Contraindications

Use of a medicinal compound is prohibited when:
    ophthalmoplegic, hemiplegic, and also basilar form of migraine;
    hypersensitivity;
    ischemic heart disease;
    hypertension;
    myocardial infarction;
    diseases of peripheral arteries, which are occlusal in nature;
    renal failure;
    stroke;
    epilepsy;
    hepatic insufficiency;
    pregnancy, and also during lactation;
    angina pectoris.
In addition, the drug is not recommended for use in the treatment of patients under the age of 18 or elderly people over 65 years of age.

Side effects

During the use of the drug, side effects can be expressed:
    in a sudden decline, and then an increase in the level of blood pressure;
    in the development of tachycardia and bradycardia;
    in violation of the heart rhythm;
    in the occurrence of nausea;
    in increasing the activity of liver transaminases;
    in the development of dysgraphia, as well as ischemic colitis;
    in dizziness, as well as drowsiness and weakness;
    in epileptic fits;
    in diplopia and decreased visual acuity;
    in the occurrence of rashes on the skin, accompanied by itching or anaphylactic reactions.
In some cases, sumatriptan may provoke the development of Raynaud's syndrome, as well as manifestations of myalgia symptoms.

Guideline for the use of sumatriptan (Method and dosage)

In accordance with the instructions for sumatriptan, the drug is taken orally immediately after the onset of a migraine attack. If necessary, relief of acute attacks adult patients can take 50-100 mg. Drinking the tablets with water.
In case of a repeated migraine attack, it is possible to take once again the minimally recommended dose of Sumatriptan (50 mg.) After at least 2 hours from the first use of the drug. It is worth noting that the maximum allowed medica dosage of the drug should not be more than 300 mg / day.

Overdose

When an overdose of the drug in patients, there are previously described adverse reactions. In such cases, immediately consult a doctor and stop using the medication.

Interaction

To avoid the development of serotonin syndrome, increase the bioavailability of moclobemide, the risk of additive hyperstimulation, and the development of side effects, sumatriptan should not be used in conjunction with lithium salts, moclobemide, rizatriptan and St. John's Wort.

Storage conditions

Sumatriptan should be stored at a temperature not higher than 25 ° C in a place protected from light and inaccessible to children.
Shelf life - 3 years.

special instructions

This drug is not intended to prevent migraine attacks. It is worth remembering that after taking sumatriptan, an allergic reaction may develop in patients with hypersensitivity to sulfonamides.
Since the use of the drug can have a negative effect on the cardiovascular system, the drug is not prescribed to patients from the so-called risk group (CHD development factor, men after 40 years, and also women in the post-climatic period) without a preliminary examination.
Before prescribing the drug, the first time to exclude other neurological diseases in patients. In addition, it is worth remembering that patients with migraine can develop a stroke, which will damage the blood circulation in the brain.
During the use of this medication, care should be taken with particular caution in the management of vehicles, as well as in any other activities that require close attention.

Children

It is not recommended to use the drug in the treatment of children under the age of 18 years.

During pregnancy (and lactation)

Sumatriptan is contraindicated in pregnancy. It is not recommended to continue breastfeeding within 24 hours after using the medication.

Reviews of Sumatriptan

Although some patients are satisfied with the drug and leave good reviews about Sumatriptan, others as a negative factor note the presence of a fairly impressive list of side effects. Therefore, many refuse effective in the fight against migraine drug only in order to avoid the development of side illnesses and diseases.