Ambrohexal syrup 6mg/ml 100ml

Instruction for Ambrohexal

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Composition

Syrup Ambrohexal. 5 ml of active ingredient syrup - 0.015 mg + excipients (benzoic acid, essence of raspberry monohydrate, sorbitol p-op, polyvidone, sodium cyclamate, sodium metabasulfite, water, sodium hydroside, glycerol).

Form of issue

    Round and flat tablets (white, with rounded edges) with a risk on one side. Packages of 20, 30, 50 and 100 pieces.
    White capsules of gelatin, inside - white or pinkish powder. Packages of 10, 20, 50 or 100 pieces.
    Transparent, slightly yellowish viscous syrup. In bottles of 100 or 250 ml, complete with a measuring spoon.
    Ambroheksal solution for inhalations and oral administration - transparent, without color. In bottles with a dispenser and a measuring cup of 50 and 100 mg.

pharmachologic effect

Expectorant. Mucolytic.

Pharmacodynamics and pharmacokinetics

The active substance - ambroxol belongs to the group of benzylamines. It restores the normal balance between the serous and mucous component of the bronchial secretion, by raising the secretion of the mucosa and directly affects the active cells in the bronchial glands. The substance stimulates the activity of special villi of the respiratory tract, thereby facilitating its movement through the bronchi. Also, ambroxol hydrochloride has the property of reducing the viscosity of phlegm by depolymerizing mucopolysaccharides. The amount of bronchial secretion does not increase, the stimulation of the centers that cause coughing does not occur.
In the time interval from half an hour to three hours, with oral intake of tablets, the drug reaches a maximum concentration in the lungs. About 90% of the substance binds to blood proteins. Most drugs are excreted by the kidneys after 6-11 hours, after administration as glucuronide (or unchanged), the rest is metabolized in the liver tissues.

Indications for use

From what appoint or nominate tablets?
    bronchitis acute or chronic;
    pneumonia;
    bronchiectatic disease;
    tracheitis;
    bronchial asthma (bronchial secretion deficiency);
    for prevention before surgery;
    Pregnant women, when there is a threat of premature delivery (28-34 weeks).

Contraindications

    drug allergy to ambroxol and other constituents;
    the first trimester of pregnancy;
    stomach ulcer, liver and kidney disease;
    children under 6 years;
    For children under 12 years of age, the use of prolonged-action capsules is not recommended.

Side effects

    nausea, pain in the epigastric region, dry mouth, diarrhea;
    dryness in the nasal cavity or opposite excessive secretion;
    allergic reactions, incl. on the skin;
    general weakness, dysuria.
When using a syrup or drops, specific reactions to metabisulphite (diarrhea, shock, loss of consciousness, nausea, asthmatic attacks) may develop.

Instructions for use Ambrohexal (Method and dosage)

When taking tablets, the daily dose for an adult (over 12 years) in the first three days is 90 mg per day, divided into 3 doses. Further, the dosage can be reduced to 60 mg. Children (from 6 years old) are prescribed 30-45 mg per day.
For prolonged-action capsules, the main condition is to maintain the integrity of the envelope upon admission. Assign, as a rule, 75 mg of the drug (1 table) after eating, once a day. It is not recommended to use children under 12 years old.
Syrup is prescribed to adults (from 12 years old) to 30 mg (2 measuring spoons) 3 times a day, the first few days. Next - the same amount 2 times a day. The maximum daily dose is 60 mg.
Children from 5 years - 1 spoon 3 times a day, from 2 to 5 - half a spoon, up to 2 years - half a spoon 2 times a day.
According to the instructions for Ambrohexal for inhalation, adults are prescribed 80 drops 3 times a day, the first days, then 80 drops 2 times a day. Children under 12 years - 40 drops 3 times a day, up to 5 years - 20 drops 3 times a day, up to 2 years - 20 drops 2 times a day.
The solution for ingestion and inhalation can be diluted in tea, juice, milk or water.

How to dilute droplets for inhalation?

To increase the drug should be 0,9%. solution, in equal proportions of approximately 50% by 50%. The prepared solution should be heated to 40-50 degrees. Inhale couples for children should be within 2-3 minutes, adults - up to five minutes.
Adult (older than 5 years) inhalation is produced twice a day, diluted 50 drops each.
For children under 5 years, 40 drops are diluted, inhalation - 2 times a day.
Do not use the drug in any of the species for more than five days, without seeing or consulting a doctor.

Overdose

Occurs extremely rarely.
The most common symptoms are: hypersalivation, vomiting, diarrhea, arterial hypotension. Treatment - according to the manifested symptoms.

Interaction

It can be combined with drugs prescribed for bronchial asthma.
With caution apply antibiotics (erythromycin, amoxicillin, cefuroxime), so there is an increase in their concentration in the body.
It is not recommended to combine with codeine and other antitussive agents.

Terms of sale

To buy Ambrohexal the prescription is not needed.

Storage conditions

Closed, dark, cool place.
Shelf life - 4 years.

Lasolvan or Ambroghexal - which is better?

Both preparations contain the same active substance ambroxol. The effectiveness of the impact is approximately the same. The cost of Ambrohexal is lower than that of its analog Lasolvan.

In pregnancy and lactation

When pregnancy is in the first trimester, the drug is not allowed.
Possible use in the second and third trimester, after consulting a doctor.
When breastfeeding, a sufficient amount of active ingredient is released with milk, so you should consult a specialist.

Reviews about Ambrohexal

Reviews for Ambrohexal tablets are good. Helps with a strong dry cough, almost no side effects. Many of the advantages of the drug are its low cost and high availability. The syrup has about the same popularity and characteristics, has a pleasant sweet taste. Typically, a cough occurs within a week after the start of treatment with the drug.
Reviews for inhalation solution - positive. Convenient form of release, high efficiency and speed of recovery are the main advantages of the drug. Many people use inhalations with Ambrohexal and saline for young children and are happy with the result. The disadvantage is the unpleasant taste of this form of the drug.