Lasolvan Rhino spray 82mcg/dose 10ml
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User manual for Lasolvan RhinoYou can buy Lasolvan Rhino hereComposition1 ml of nasal spray contains 1.18 mg of the active ingredient tramazoline in the form of hydrochloride.Additional components: benzalkonium chloride, Na hydrox..
User manual for Lasolvan Rhino
You can buy Lasolvan Rhino here
1 ml of nasal spray contains 1.18 mg of the active ingredient tramazoline in the form of hydrochloride.
Additional components: benzalkonium chloride, Na hydroxide, citric acid monohydrate, racemic camphor, levomenthol, eucalyptol, Na hydrogencarbonate, povidone, purified water, calcium chloride dihydrate, magnesium sulfate heptahydrate, glycerol, hydroxypropylmethylcellulose, magnesium chloride hexahydrate.
Form of issue
Almost transparent solution with a pale yellow tint, with a specific smell of eucalyptus. Spray is produced in bottles of dark glass of 10 ml, equipped with a nasal adapter and a special device-dispenser. In the cardboard box is an instruction and 1 bottle.
Tramazoline is an alpha-adrenomimetic. The drug has a vasoconstrictive, anticonvulsant effect.
The active substance contributes to the narrowing of the lumen of the vessels, which allows to reduce the manifestation of puffiness when applied to the mucous membranes of the nose. The medicine permanently facilitates nasal breathing and restores the patency of the nasal passages in the rhinitis. The effect develops 5 minutes after application of the spray and lasts 8-10 hours.
Pharmacodynamics and pharmacokinetics
Pharmacokinetics of the drug was studied in rabbits, rats and monkeys. On a man, pharmacokinetic studies were not conducted.
After applying Lasolvan Rhino intranasally or inward, the active substance is absorbed by 50-80%. The maximum concentration is recorded in the hepatic system, and the active component and its metabolites are found in all internal organs. After local, oral administration, the main metabolic products are found in the urine. The half-life (terminal) is 5-7 hours.
Indications for use
eustachiitis (otitis media);
nasal congestion with hay fever, rhinitis, pollinosis, SARS;
swelling of the nasal mucosa.
With sinusitis and eustachytes, Lasolvan Rhino spray is relieved by increased outflow of contents from the nasal adnexal sinuses.
individual hypersensitivity (allergic reactions in the anamnesis for benzalkonium hydrochloride, tramazolin hydrochloride);
closed-angle form of glaucoma;
surgical interventions on the skull through the nasal cavity in the anamnesis.
In pediatric practice can be used from 6 years.
hypertrophy of the prostate;
simultaneous therapy with MAO inhibitors;
reception of tricyclic antidepressants;
pathology of the cardiovascular system;
taking vasopressors, antihypertensive drugs;
With these conditions and diseases, the risk of systemic absorption of the active substance increases.
violation of taste perception;
increased blood pressure;
a feeling of palpitations;
swelling of the nose;
dryness in the nose;
hypersensitivity reactions, allergies;
swelling of the skin;
itching of the skin;
Lasolvan Rhino, instructions for use (Method and dosage)
In pediatric practice (from 6 years) and adults prescribe a spray according to the standard scheme: in each nasal passage of 1 injection (a day can be carried out no more than 4 injections). Uncontrolled use of the drug is unacceptable. The drug can be used no more than 5-7 days.
Instructions for use Lasolvan Rhino also includes rules for the use of a special dosing device:
Remove the protective cap from the bottle.
Carry out several injections into the air before forming a stable aerosol cloud. Now the device is ready for full use.
Clean the nasal passages and insert the tip into the nose, then inject. Repeat for the second nasal passage. Make a normal breath through your nose after removing a special tip.
Put a protective cap on the bottle.
The tip should be cleaned after each use.
The first signs of an overdose are rapid heart rate and blood pressure rise, followed by reflex bradycardia, shock, possibly lowering the body's overall temperature. Similarly to other alpha-sympathomimetics, the clinical symptoms of poisoning are fuzzy, The phases of depression and stimulation of the central nervous system and cardiovascular system consistently replace each other.
In children, seizures, coma, respiratory depression, bradycardia develop. Signs of a stimulating effect on the central nervous system are hallucinations, agitation, anxiety and the development of convulsive syndrome. With the suppression of the nervous system, there is sluggishness, a decrease in the overall body temperature, increased drowsiness.
respiratory failure (respiratory arrest, respiratory failure);
cyanosis of the lips;
disturbances in the work of the cardiovascular system (up to cardiac arrest).
With a nasal overdose, the nose is cleaned and the nasal passages washed. If necessary, post-prandial therapy is performed.
Perhaps the development of arrhythmia with the simultaneous administration of tramazolin and tricyclic antidepressants. Against the background of treatment with antihypertensive drugs can manifest a variety of cardiovascular effects. This effect is more pronounced when taking medications that affect the sympathetic department of the nervous system. The increase in blood pressure is recorded when treated with MAO inhibitors, some antidepressants.
Terms of sale
To buy Lasolvan Rhino is not necessary to present a prescription form to a pharmacist.
Transport and storage of vials with a solution is allowed if the temperature regime is observed - up to 25 degrees.
Shelf life - 3 years.
In the absence of positive dynamics in the first week of treatment, a doctor's consultation is recommended with consideration of discontinuing therapy or continuing treatment. Prolonged uncontrolled use of vasoconstrictor nasal agents can provoke the development of atrophy of the nasal mucosa, the formation of a chronic inflammatory process, or cause nasal congestion. It is inadmissible to get a solution of tramazolin in the eyes.
Special studies on the possible effects of medication on a person's ability to manage complex machines, mechanisms and driving vehicles were not conducted. Considering that the manufacturer claims such undesirable reactions as dizziness, drowsiness, hallucinations, fatigue, sedation, it is recommended to refrain from driving by car during the treatment of Lasolvan Rhino.
Lasolvan Rhino for children
In pediatric practice, medication can be used for children older than 6 years.
Lasolvan Rhino during pregnancy and lactation
Sufficiently long experience of prescribing a drug to pregnant women has not revealed a negative effect on the course of pregnancy and fetal development. There is no data on the absolute safety of spray application in lactation.
The manufacturer does not recommend the use of the drug in the first trimester of pregnancy. When breastfeeding and during pregnancy at late gestation (2/3 of pregnancy), a medication can be prescribed by the decision of the treating doctor.
Reviews of Lasolvan Rhino
The drug can effectively fight the manifestations of the common cold, facilitating the course of the main symptoms: nasal congestion, runny nose. The drug is well tolerated, with little or no negative symptoms.
With prolonged use, atrophy of the nasal mucosa is formed. Patients write reviews that the drug allows you to get rid of the common cold in a matter of minutes, without the development of a dry nose sensation characteristic of drugs of a similar effect.