Next tabs 400mg + 200mg #20

Next tablets instruction for use

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Form of release and medicinal composition of the preparation

The drug Next is available in the form of tablets for oral administration in blisters for 2, 6, 10 or 12 tablets in a cardboard box, where the instruction is enclosed with a detailed description.
Each tablet contains active active ingredients:
    Ibuprofen 400 mg;
    Paracetamol 200 mg.
In addition, the preparation includes a number of auxiliary components.

Pharmacological properties

Tablets Next is a combination of medicines that exerts a pronounced analgesic, anti-inflammatory and antipyretic effect on the body. Included in the tablet active ingredients suppress the synthesis of prostaglandins - the main stimulant of inflammatory processes in the body.
Against the background of the treatment, the pain decreases in the joint region at rest, the endurance of the joint increases to physical loads, the morning stiffness and swelling of the inflamed joints decrease under the influence of the drug.
The drug can be used as part of complex therapy for various pain syndromes and acute respiratory viral infections, accompanied by fever.

Indications for use

The drug Next is assigned to patients under the following conditions:
    Tension headaches, severe migraine;
    Toothache;
    Muscle pain;
    Painful menstruation in women;
    Neuralgia;
    Pain in the back, lower back;
    Pain in the joints;
    Post-traumatic pain;
    Pain caused by the inflammatory process of the musculoskeletal system;
    Pain caused by bruises, sprains;
    As part of complex therapy for acute respiratory viral infections;
    Fever.

Contraindications to use

The drug can be taken only as directed by a doctor. Before starting therapy, you should carefully read the instructions, since the drug has a number of the following contraindications:
    Increased individual sensitivity to the constituents of the preparation;
    Suspicion of stomach ulcer or diagnosed ulcer;
    Gastrointestinal bleeding or suspicion of it;
    Erosive ulcerative colitis;
    Impaired liver and kidney function, severe hepatic or renal insufficiency;
    Violations of the coagulated function of blood, severe genetic diseases - hemophilia, hemorrhagic diathesis, increased tendency to bleeding;
    Bronchial asthma or history of bronchospasm;
    Individual intolerance to acetylsalicylic acid;
    Recently transferred surgery on the aorta, coronary artery bypass graft;
    Elevated levels of potassium in the blood, confirmed by laboratory tests;
    Pregnancy 1 and 3 trimesters;
    Age at children till 12 years;
    Breastfeeding period.
To relative contraindications (when the medicine can be used only in rare cases) are:
    Chronic heart failure;
    Intoxication of the body with alcohol;
    Hepatic or renal failure with moderate organ impairment;
    Gastritis;
    The age of patients older than 60 years.

Method of administration and dosage regimen

The tablets are intended for oral use. To reduce the irritant effect of the active ingredients on the mucous membranes of the digestive tract, tablets are best taken after meals, immediately swallowing without chewing.
According to the instruction, adult patients are prescribed 1 tablet no more than 3 times a day. Children from 12 years - no more than 2 tablets per day. The duration of the course of therapy with the drug should not exceed more than 3-5 days, since in this case the risk of developing serious side effects is significantly increased. In the absence of the expected therapeutic effect, the patient should consult a doctor to clarify the diagnosis and correction of the prescribed treatment.

Using Next in pregnancy and lactation

Since all the organs and systems of the fetus are laid in the first trimester of pregnancy, the use of any medications, including the tablets of Next, is contraindicated.
The use of the drug in the second trimester of pregnancy is possible only for life indications, in those situations when the expected benefit for the mother will far exceed the possible danger to the fetus. Treatment is carried out under the constant supervision of a specialist.
The use of the drug in the third trimester of pregnancy is contraindicated in women, as in this case the risk of bleeding in the fetus and newborn increases, as well as the high probability of bleeding in the parturient woman during labor.
Since the active ingredients are excreted in breast milk, the use of NEXT tablets is contraindicated during lactation. If it is necessary to use the drug, a woman should stop feeding her baby temporarily.

Side effects

If the drug is used for more than 3 days, the risk of developing side effects increases with the following clinical symptoms:
    On the part of the organs of the digestive canal - pain in the stomach, nausea, lack of appetite, diarrhea or constipation, exacerbation of chronic diseases of the digestive tract, development of peptic ulcer and erosive colitis;
    On the part of the liver - an increase in the liver and an increase in liver transaminase activity, in severe cases, development of hepatic insufficiency is possible;
    Development of interstitial nephritis, acute renal failure;
    Eruption on skin of erythematous nature;
    in persons with bronchial asthma, there is an increase in the history and aggravation of asthmatic attacks, bronchospasm;
    from the cardiovascular system - changes in blood pressure, tachycardia, heart failure.

Overdose

With prolonged use of the drug in large doses, the patient may develop signs of overdose, which are expressed in the enhancement of the above-described side effects and the development of severe hepatic and renal failure. If such symptoms appear, the patient should immediately be taken to a hospital where the stomach is rinsed, enterosorbents are administered and if necessary, symptomatic treatment is performed.

Interaction of the drug with other drugs

With the simultaneous appointment of the drug Next with Phenytoin, Rifampicin, Phenylbutazone and tricyclic antidepressants, the risk of toxic liver damage and the development of severe overdose increases in patients.
When the drug is combined with glucocorticosteroids, Ibuprofen, ethanol, the risk of erosive and ulcerative lesions of the mucous membranes of the gastrointestinal tract increases.
With the simultaneous administration of this drug to medicines containing Paracetamol, the risk of toxic liver damage is significantly increased in patients.
Long-term use of barbiturates reduces the therapeutic effect of paracetamol, which is part of the drug. Antacids and enterosorbents reduce the absorption of Ibuprofen and Paracetamol, which significantly reduces the therapeutic effect of the drug Next.
The drug is not recommended at the same time to appoint with anticoagulants or Acetylsalicylic acid, as this drug interaction increases the risk of bleeding.

Next tablets special instructions

When using the drug for more than 5 days, the patient should monitor liver function and the basic parameters of blood parameters. At the slightest violations in the work of the liver, the drug should be discontinued.
During drug treatment, you should avoid driving or complicated equipment that requires quick response.

Terms of leave from pharmacies and storage

To buy Next tablets the prescription is not required. Tablets should be stored in a cool dark place out of the reach of children. Shelf life of the drug is indicated on the package and is 3 years from the date of manufacture, after which the drug should not be taken orally.