Lancid caps 30mg #30

Lancid instruction for use

You can buy Lancid on this page

Composition

In one capsule of Lancid, depending on the dosage, there may be 15 or 30 mg of lansoprazole.

List of excipients

Mannitol, lactose monohydrate, sucrose, povidone, hypromellose phthalate, cetyl alcohol.

List of hard gelatin capsule components

Enter the body and cap: gelatin, sodium lauryl sulfate, propyl parahydroxybenzoate, methyl parahydroxybenzoate, titanium dioxide, water. Depending on the dosage, the dyes differ: 15 mg - a brilliant blue dye, quinoline yellow dye; 30 mg is a crimson dye (Ponce 4R).

Form of issue

Lancid 15 mg
Issued in capsules of size 3 turquoise (content - white granules), bearing the inscription MICRO / MICRO. In one package there are 3 blisters with 10 capsules.
Lancid 30 mg
Issued in capsules of size 1, having a pink color and the inscription MICRO / MICRO. In one package there are 3 blisters with 10 capsules.

pharmachologic effect

Characteristic of the drug antiulcer effect.

Pharmacodynamics and pharmacokinetics

Lancid has a high lipophilicity and is able to easily penetrate into the cells of the stomach, concentrate in them and protect, increasing the secretion of bicarbonates. In addition, the formation of hydrochloric acid is slowed down already when using a therapeutic dose of 30 mg (80-97%), without affecting the motility of the gastrointestinal tract. Increasing the effect is observed in 1-4 days and with the withdrawal of the drug secretory activity is gradually restored.

Information on pharmacokinetics

Absorption is highest and maximum concentration with the intake of 30 mg is observed after 1.5-2 hours and reaches 0.75-1.15 mg / l. Binding in the blood occurs at 98%. The half-life is from 1.3 to 1.7 hours. Metabolism active in the liver, excretion - metabolites by the kidneys (14-23%), the rest - through the intestine.

Indications for use

    ulcerative defects in the stomach and duodenum (exacerbation);
    various degrees of erosive-ulcerative esophagitis;
    reflux esophagitis;
    tumors in the islet apparatus of the pancreas;
    nonulcer indigestion.

Contraindications for Lancid

    patients with malignant neoplasms of the gastrointestinal tract (mandatory endoscopic control is required, because it is possible to hide symptoms and delay correct diagnosis);
    lactation, first trimester of pregnancy;
    known sensitivity.

Use with caution

    liver failure;
    second and third trimesters of pregnancy;
    elderly patients and children under 18 years old.

Side effects

    Digestive system: increased or decreased appetite, nausea, abdominal pain, diarrhea or constipation, development of ulcerative colitis, candidiasis, hyperbilirubinemia.
    Nervous system: headache, malaise, dizziness, depression, drowsiness, anxiety.
    Respiratory system: cough, pharyngitis, upper respiratory tract infection, rhinitis, flu-like syndrome.
    Organs of hematopoiesis: thrombocytopenia, complicated by hemorrhagic manifestations, anemia.
    Allergic side reactions: photosensitivity, skin rash, erythema multiforme.
    Other: myalgia, alopecia.

Lancid, instructions for use (method and dosage)

Take capsules should be inside, swallowing and not chewing.

Recommended daily dose and course for various diseases

    ulcerative defects in the stomach and duodenum and stress ulcers: 30 mg in the morning, before eating; the course usually lasts 2-4 weeks;
    various degrees of erosive-ulcerative esophagitis: 30-60 mg; the course usually lasts 4-8 weeks;
    reflux esophagitis: 30 mg 4 weeks;
    tumors in the islet apparatus of the pancreas: the dose must be selected individually in order to reach the level of basal acid production no more than 10 millimoles / h;
    eradication of Helicobacter pylori - 60 mg divided into 2 doses in combination with antibiotics, for example: Clarithromycin and Amoxicillin, the presumptive course is 1 week;
    non-ulcer indigestion: 15-30 mg 2-4 weeks.

Correction for specific patient groups

These include elderly patients, as well as those suffering from liver failure - initiation of treatment is done using half the dose, and then gradually increase their minimum to 30 mg.

Overdose

No data.

Interaction

    With drugs metabolized in the liver along the path of microsomal oxidation, a slowdown in their elimination occurs, including Diazepam, Phenytoin, indirect anticoagulants, and the clearance of Teofillin decreases by 10%.
    With weak acids their pH-dependent absorption is slowed down, with bases - on the contrary, absorption is accelerated. Lancid interferes with absorption of Ampicillin, ketoconazole, iron salts, Digoxin.
    With Sucralfate, the bioavailability of lansoprazole is reduced by 30%, which requires keeping the interval between their doses in 30-40 minutes.
    With antacids, the recommended interval is 1-2 hours of communication with deceleration and a decrease in their absorption when combining drugs.

Terms of sale

To buy Lancid you don't need a prescription.

Storage conditions

For storage of Lancid is best suited dry, protected from light (temperature not more than +25 ° C), inaccessible to children space.
Shelf life - 24 months

Reviews of Lancid

Do not use the drug with a combination drug such as Lancid Whale, which has additional active substances - Clarithromycin and Amoxicillin.