Omez caps 20mg #30

Instruction for Omez

You can buy Omez online

Composition

The capsules contain the active ingredient omeprazole, as well as additional substances: sodium dihydrogen phosphate, sucrose, sodium lauryl sulfate, purified water. The drug is also available as a lyophilized powder, which is used to prepare the solution. It also includes the active ingredient omeprazole, as well as an auxiliary anhydrous sodium carbonate.

Form of issue

The form of the preparation is capsules and powder.
Capsules of gelatin are hard, the capsule body is transparent, the lid is pink. The inscription "OMEZ" is on both parts of the capsule. The capsule is filled with white granules. The package contains 10 or 30 capsules.
It is also available as a lyophilized powder from which a solution for indium is prepared (Omez IV). The bottle contains 40 mg of the drug.

pharmachologic effect

As an abstract, this drug is an antiulcer drug that belongs to the group of proton pump inhibitors. The active substance omeprazole, which contains capsules, inhibits the secretion of hydrochloric acid, having a specific effect on the enzyme H + -K + -ATP-ase of the cells of the stomach. As a consequence, under its influence the last stage of synthesis of hydrochloric acid is blocked. As a result, regardless of the type of stimulus, the level of basal and stimulated secretion decreases.

Pharmacodynamics and pharmacokinetics

The use of the drug internally leads to a rapid development of the effect: it manifests itself within 1 hour. Next, Omez tablets are active for 24 hours.
After the medication is stopped, the secretory activity of the exocrine glands of the stomach is restored after about 3-5 days. For omeprazole is characterized by rapid absorption from the intestine. Since the active substance in the preparation is contained in granules resistant to acid, they dissolve only in the intestine. In plasma, the highest concentration is observed after 30-60 minutes. The bioavailability level of omeprazole is 40%. The drug is associated with plasma proteins - 90%. It is metabolized in the liver.
It is excreted through the kidneys.
When administered intravenously, there is a dose-dependent inhibition of gastric secretion. The half-life of omeprazole after intravenous administration is approximately 40 minutes.

Indications for use of Omez

Indications for the use of Omez are as follows:
    peptic ulcers of the duodenum, stomach;
    erosive-ulcerative esophagitis;
    ulcerative processes that are associated with treatment with nonsteroidal anti-inflammatory drugs;
    an ulcer associated with stress;
    peptic recurrent ulcers of gastric or duodenal localization;
    Zollinger-Ellison syndrome;
    pancreatitis;
    gastroesophageal reflux disease;
    systemic mastocytosis.
If there is no possibility of taking the drug inside, but there are indications for use, the agent can be administered intravenously.
When to drink Omez tablets, from what else they are applied, will inform the attending physician.

Contraindications to Omez

There are the following contraindications:
    hypersensitivity;
    pregnancy and feeding;
    childhood.
Caution capsules should be taken to people with renal and hepatic insufficiency. The method of application and dosage in this case should be determined only by a specialist.

Side effects of Omez

In general, side effects in the treatment of these drugs are rare. The following side effects are possible:
    Digestive system: abdominal pain, nausea, flatulence, taste disorders, increased activity of liver enzymes.
    Organs of hematopoiesis: thrombocytopenia, leukopenia, agranulocytosis.
    Nervous system: headache, dizziness, depression.
    Musculoskeletal system: myasthenia gravis, arthralgia, myalgia.
    Skin: rash, itching of the skin, photosensitivity.
    Allergic manifestations: urticaria, fever, bronchospasm.
    In addition, in rare cases, there may be visual disturbances, malaise, severe sweating.

Instructions for use Omez (Method and dosage)

The patient should swallow capsules without opening or chewing.
If a peptic ulcer, reflux-esophagitis is prescribed Omez tablets, the instruction for use provides that the drug is administered at a dose of 20 mg per day, in the morning, on an empty stomach. The drug should be taken 14 days. If the peptic ulcer did not heal during the treatment period, the treatment may continue for another two weeks. As a rule, when taking the remedy cicatrization peptic ulcer of the duodenum occurs in 4 weeks.
Treatment of Zollinger-Ellison syndrome provides for taking 60 mg a day. On how to drink - before or after eating, the instructions also have an indication: the drug is taken before meals. Supportive doses are further prescribed by a physician.
When gastritis treatment lasts from 1 to 2 weeks. Treatment of gastritis is aimed at eliminating the symptoms of irritated stomach. In this case, 1 capsule per day is prescribed. In addition, how to take Omez with gastritis, tell the doctor after diagnosis.
When pancreatitis is appointed as part of a comprehensive treatment. It is assumed that such treatment helps to relieve the patient of heartburn, reduce pain and stress on the pancreas. The duration of treatment depends on the severity of the symptoms. Initially, two capsules are prescribed per day, then maintenance therapy is used - 1 capsule per day. For heartburn, do not use without prior approval of such treatment by your doctor.
The introduction of intravenously, depending on the disease, is carried out at a dose of 40 mg of 80 mg per day. If the dose is from 60 mg, it can be divided into two injections. After the removal of acute symptoms, the practice of switching to oral administration of the drug is practiced. The prepared solution is suitable for 24 hours.

Overdose

Wikipedia indicates that an overdose of the drug does not lead to life-threatening symptoms. In this case, blurred vision, dry mouth, drowsiness, headaches, tachycardia may occur. Symptomatic therapy is used. Hemodialysis is not effective enough.

Interaction

With simultaneous administration, the level of absorption of esters of ampicillin, iron salts, ketoconazole, itraconazole can decrease.
Omeprazole increases the concentration and reduces the activity of excretion of diazepam, anticoagulants of indirect action, phenytoin.
With the combined use of oral omeprazole and clarithromycin, the concentration of these substances in the blood plasma increases.

Storage conditions

Store the product in a dry and dark place, at an air temperature not exceeding 25 ° C.
Shelf life of the capsules is 3 years.

special instructions

It is possible to take capsules at the same time as food, from which the medicine does not lose its effectiveness.
Before starting to take capsules or drive Omega intravenously, it is necessary to exclude malignant processes, since therapy can mask symptoms, thereby, otstrachivaya diagnostics.
Sometimes there are circumstances when it is necessary to avoid swallowing an entire capsule, for which the medicine is used in the following way: the capsule is opened, and its contents are mixed with a soft apple puree (1 tablespoon). In other ways, you can not take the contents of the capsule.
It is unlikely that the drug will affect the ability to drive vehicles and work with accurate equipment.

Children

The medicine is not prescribed for children under 12 years of age, since there is not enough information about its effect on the body of young patients.

With alcohol

Compatibility with alcohol: in spite of the fact that there is no information in the manual that alcohol is prohibited in the treatment with omeprazole, according to doctors, when drinking drugs, you should not drink alcohol.

Omez during pregnancy and lactation

When pregnant and breast-feeding a child, treatment with this drug is not practiced.

Reviews about Omez

There are numerous positive reviews about Omez. Feedback from the host shows that it effectively cures peptic ulcer, helps to overcome heartburn, removes the symptoms of acute gastritis. Reviews about Omez on the forms are also positive, people note that it can be taken at any time, and it acts equally effectively. In addition, the drug improves the state of the gastrointestinal tract when treated with other drugs that act on the stomach and intestines irritatingly. As a shortcoming, it is often mentioned that the tool is quite expensive.