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Clotrimazolum cream 1% 20gr

  • $9.33
  • 3 or more $9.15
  • Availability:In Stock

Cream Clotrimazolum instructionYou can buy Clotrimazolum on this pageCompositionThe composition of the cream is 1%: Clotrimazolum at a concentration of 10 mg / g, cetostearyl and benzyl alcohol, polysorbate 60, synthetic spermacet..

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Cream Clotrimazolum instruction

You can buy Clotrimazolum on this page


The composition of the cream is 1%: Clotrimazolum at a concentration of 10 mg / g, cetostearyl and benzyl alcohol, polysorbate 60, synthetic spermaceti, octyl dodecanol, sorbitan stearate, water.

pharmachologic effect


Pharmacodynamics and pharmacokinetics

Clotrimazolum is a derivative of imidazole.
In vitro is highly active against the most pathogenic fungi that can cause serious infectious complications, namely:
    dermatophytes (Microsporum sp., Epidermophyton floccosum, Trichophyton sp.);
    yeast-like fungi (Cryptococcus neoformans, Candida sp.);
    dimorphic fungi (Histoplasma capsulatum, Paracoccidicides brasiliensis, Coccidiodes immitis).
The mechanism of action of Clotrimazolum is based on its ability to block the synthesis of proteins, nucleic acids and the necessary for the construction of cellular membranes of ergosterol fungi. As a result, the cell walls of the fungi are damaged, and the cells die.
In low concentrations, Clotrimazolum acts fungistatically. If the dose exceeds 20 μg / ml, the drug has a fungicidal effect, not only on proliferating cells.
In case of application in high doses, it helps to increase the concentration of hydrogen peroxide in a fungal cell to a toxic value and, as a consequence, to the destruction of fungal cells
When topical application of the drug is absorbed by the epidermis. The highest concentration of the substance is determined in the reticuloderm. It is also able to penetrate the nail keratin.
In systemic circulation Clotrimazolum falls in very small amounts. Metabolised in the liver to inactive substances, which are excreted from the body with feces and urine.
With intravaginal application, 5 to 10% of Clotrimazolum is absorbed. Metabolization of the absorbed substance is exposed in the liver. Derived products of metabolism with bile.

Indications for use: for what ointment, cream, gel Clotrimazolum?

The drug is prescribed for the treatment of fungal infections of the skin, which are caused by mold and yeast fungi, dermatophytes and other pathogens sensitive to Clotrimazolum.
They are also used as a remedy for lichen caused by Malassezia furfur, and erythrasms (pathogen - Corynebacterium minutissimum).
Helps ointment, cream, gel and Clotrimazolum solution: from the fungus of nails (onychomycosis, fungal paronychia), trichophytosis, dermatophytosis, fungal erosion and intertrigo, candidamycosis, microsporia, epidermophytosis, dermatomycosis complicated by secondary pyoderma mycoses.
Indications for the use of ointment, gel, cream and solution are including infectious diseases, pathogens that are resistant to nystatin and a number of other antifungal agents.
To treat pink depriving the drug is not suitable, since this disease is most likely to be of viral or infectious-allergic origin, and may also be the response of the body to severe shock or nervous breakdown. Clotrimazolum is also effective in fungal infections.
The use of Clotrimazolum ointment, gel and cream with Clotrimazolum in gynecology is shown:
    for treatment and prophylaxis of thrush;
    for the prevention of repeated fungal infections of the female reproductive system that develop with prolonged treatment with antibiotics or against the background of immunodeficiency states.
Also, the solution, gel, cream and ointment in gynecology is used to sanitize the genital tract before delivery.


Contraindications: hypersensitivity.

Side effects

Allergic reactions.
When applied to the skin, the following side effects are possible:
    the appearance of blisters;
    skin irritation;
    tingling sensation
Local application in urogenital fungal infections may be accompanied by burning, itching, puffiness and hyperemia of the mucosa, intercurrent cystitis, the appearance of vaginal discharge, increased urination, pain during intercourse.
In topical application with mycosis of the oral cavity, reddening of the mucous membrane, a sensation of tingling and burning at the site of application of the preparation, irritation can be noted.

Instructions for use Clotrimazolum: Clotrimazolum for women and for men

Cream Clotrimazolum: instructions for use

The cream is for topical application. With thrush and other fungal diseases, it is applied to the affected parts twice or thrice during the day and lightly rubbed.
If mikoparazitami hit the genitals, for treatment of thrush cream is prescribed simultaneously to both partners. With candida balanitis or balanoposthitis cream with Clotrimazolum for men is used in the same way as ointment.
The duration of the course depends on the indications for use and ranges from 1-2 (with candida balanitis / vulvitis) to 3-4 weeks (with dermatomycosis).
To prevent recurrence of the disease, it is very important not to discontinue the treatment for another 2 weeks after the subjective symptoms of the infection have disappeared. In the absence of improvement after 4 weeks of therapy, the patient should consult a doctor.
Vaginal cream Clotrimazolum is introduced into the vagina in portions of 5 grams 1 rub. / Day. within 3 days.


When applied to the skin and intravaginal application of the risk of acute intoxication is not, because Clotrimazolum enters the systemic circulation in very small quantities.
With the occasional administration of Clotrimazolum inside, nausea, anorexia, vomiting, gastralgia, and liver dysfunction are possible. In rare cases, there are pollakiuria, hallucinations, drowsiness, skin allergic reactions.
In this case, the patient is assigned enterosorbents and symptomatic treatment. Gastric lavage is performed in situations where a life-threatening dose has been taken within the previous hour, and if there are visible symptoms of an overdose (nausea, dizziness, vomiting).


When used simultaneously with polyene antibiotics (amphotericin B, natamycin, Nystatin), drugs mutually suppress each other's activity.

Storage conditions

Protect from moisture and light. Storage temperature should not exceed 25 ° C. Freezing of cream, gel, ointment or solution is not allowed.

Shelf life

Suppositories, cream, solution, gel and vaginal tablets are suitable for use within 3 years after the release date. Shelf life for the ointment is 2 years.

special instructions

Avoid ingestion and contact with eyes.
With fungal infections, all affected areas of the body should be treated simultaneously.
The use of vaginal tablets, if the doctor has not given other recommendations, is contraindicated in the presence of any of the following symptoms:
    acyclic vaginal bleeding;
    bloody discharge or pathological bleeding from the vagina, uterine hemorrhages;
    lower abdominal pain;
    open wounds, blisters or ulcers of the vagina or vulva;
    any unpleasant symptoms associated with Clotrimazolum (irritation, redness, burning, swelling, etc.);
    chills or fever with a fever above 38 ° C;
    nausea and / or vomiting;
    vaginal discharge with an unpleasant odor;
    pain in the shoulder area or in the back.
To prevent reinfection treatment is prescribed simultaneously to both partners. The optimal dosage form for men is cream.
In trichomoniasis, in addition to the drug, chemotherapeutic agents are prescribed for systemic treatment (metronidazole inside).

What is the best ointment or cream Clotrimazolum?

The choice in favor of this or that dosage form is made depending on the indications. Ointment Clotrimazolum for women and men is prescribed for diseases that are accompanied by increased dryness and flaking of the skin.
As a rule, these skin mycoses caused by dermatophytes (trichophytosis, microsporia), inguinal epidermophytia, erythrasma, pityriasis, isolated cases of candida of smooth skin, mixed bacterial and fungal infections.
When wetting inflammatory processes, it is more expedient to use a cream that has a drying effect.

Clotrimazolum for children

The experience of applying a solution, ointment, gel and cream 1% in children is absent.
Tablets are used from the age of 12 on condition that the patient has a menarche.
Candles are not assigned to children.

Clotrimazolum during pregnancy and lactation

Cream, gel, ointment, solution, candles and vag. pills during pregnancy can be applied from the 2nd trimester.
Strictly controlled studies on the safety of use during pregnancy, in connection with this Clotrimazolum is not prescribed in the first trimester.
Clinical studies on the effect of the drug on fertility in women have not been conducted, no adverse effects have been identified in animal experiments.
Tablets and candles Clotrimazolum during pregnancy (in the 2nd and 3rd trimesters) do not have a negative effect on the fetus, but the use of the applicator can be dangerous.
When breastfeeding the drug is used with caution, since it is unknown whether it penetrates into the milk.
Gel, solution, cream and ointment Clotrimazolum during pregnancy is applied to the affected skin with myoparasites 2-3 r. / Day. If vaginal pills are prescribed, they should be administered without an applicator. The duration of the course depends on the localization of pathological changes, the severity of the disease and the effectiveness of treatment.
Feedback indicates that in most cases the drug is well tolerated, and adverse reactions due to its use are very rare.

Reviews about Clotrimazolum

Solution, ointment, cream, gel, candles and vaginal tablets Clotrimazolum - reviews are eloquent confirmation of this - a time-tested, inexpensive and very effective remedy for nail and skin fungus, as well as against urogenital mycoses.
In addition, the drug is effective against age spots.
Clotrimazolum suppositories reviews on the forums are mostly the following: "Only them and I treat thrush. The remedy is cheap, but it helps perfectly. No side effects. "
Important features of Clotrimazolum, which are taken into account in its appointment, are the possibility:
    application of suppositories, tablets, ointment, solution, gel and cream from thrush during pregnancy;
    purpose cream and ointment for preventive treatment of the sexual partner of a woman.
No less good reviews of men about ointments Clotrimazolum and reviews about the cream. The only drawback of the drug, men sometimes note that it should be applied for a long time.

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