Gioxisone ointment 10gr

Instruction for Gioxisone

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Form of formulation and composition of the preparation

Gioxisone is available in the form of an ointment for external use. Ointment is a homogeneous substance of white color without any specific odor. The preparation is produced in an aluminum tube of 10 g in a cardboard bundle.
The main active ingredients of the drug are oxytetracycline hydrochloride and hydrocortisone acetate.

Pharmacological properties of the drug

Ointment Gioxisone is a combined preparation of local effects, which exerts antiallergic, anti-inflammatory, anti-edematous and antibacterial effects on the skin.
The oxytetracycline included in the preparation belongs to antibiotics from the tetracycline group, due to which the inhibition of growth and reproduction of pathogenic microflora occurs under the influence of the drug. This substance shows a high therapeutic activity against gram-positive and gram-negative microorganisms, pale treponema, rickettsia, mycopath and others.
Hydrocortisone, which is part of the preparation, is a glucocorticosteroid agent that exerts a pronounced anti-edematous, anti-inflammatory, antipruritic and anti-allergic effect. Under the influence of ointment, the patient quickly falls swelling of the skin, redness disappears, itching and local hyperthermia disappear.

Indications for use

Ointment Gioxisone is prescribed to patients for treatment of the following conditions:
    Infected wounds;
    Frontal lacerations and various skin lesions that occur with attachment of a secondary bacterial infection;
    Wet eczema and neurodermatitis;
    Erysipelas of the skin;
    Bedsores;
    Contact dermatitis;
    Insect bites;
    Hives;
    Carbuncles and boils;
    Impetigo;
    Trophic ulcers that occur against the background of the progression of varicose veins;
    Frostbite or burns, accompanied by suppuration of affected areas.

Contraindications for Gioxisone

The drug can be used to treat the pathological processes of the skin only after a preliminary consultation with a doctor. Before the start of therapy, you should carefully read the attached instructions, since Gioxisone Ointment has a number of limitations and contraindications for use. Contraindications include:
    Individual intolerance to the components of the drug;
    There are serious allergic reactions to the drugs of the tetracycline group in the anamnesis;
    Fungal or viral skin lesions;
    Necrosis of tissues;
    Pregnancy and lactation;
    Lupus;
    Severe liver or kidney damage;
    Heart failure in the stage of decompensation;
    Disturbances in the adrenal gland or thyroid gland.

Dosing and Administration

The duration of the course of therapy with the drug and the daily dose is determined by the doctor, depending on the indications and individual tolerability of the components of the ointment.
According to the instructions, the Gioxisone ointment should be applied to the affected areas of the skin, after cleaning them from the crusts and purulent contents, with a thin layer 2 times a day. At the initial stages of treatment, the drug can be applied to the affected areas up to 3 times a day, if necessary covering the wound surface with a gauze dressing.
The duration of the course of therapy with the drug should not exceed 7 days. If during this period the patient does not experience any improvement, then you should consult a doctor again in order to clarify the diagnosis and correction of treatment.

Use of the drug during pregnancy and breastfeeding

Gioxisone ointment can not be used while the child is waiting. Tetracyclines that are part of the drug have a mutagenic and teratogenic effect on the embryo in the first trimester of pregnancy, which can lead to spontaneous miscarriage or the birth of a child with anomalies and defects.
The use of ointments in the 2nd and 3rd trimesters can lead to damage to the internal organs of the fetus, since even in a small amount, but the active components of the drug are still absorbed into the systemic bloodstream and can enter the uterus through the placenta.
The use of ointment Gioxisone in the period of breastfeeding requires the cessation of lactation.

Side effects of Gioxisone

According to reviews of patients who used Gyoxisone Ointment for treatment, the drug is well tolerated and rarely causes negative symptoms. In some cases, with increased individual hypersensitivity, the following side effects may develop:
    Itching at the site of application;
    Dryness and flaky skin;
    Hyperemia of the skin;
    Burning in the place of application.
As a rule, these phenomena are poorly expressed and do not require the abolition of ointment therapy.

An overdose of the drug

With prolonged uncontrolled use of Gioxisone ointment, the patient may develop symptoms of overdose, which manifest themselves in the form of an increase in the above-described side effects and various systemic abnormalities that often occur during treatment with glucocorticosteroids:
    Dizziness;
    Heart rhythm disturbances;
    Violation of the function of the adrenal glands.
When using a large amount of ointment on the face, it is possible to develop subcutaneous tissue atrophy in the area around the mouth.
If you accidentally take ointment inside the patient should immediately wash the stomach, give take enterosorbents and deliver to the hospital.

Interaction of the drug with other drugs

Ointment Gioxisone is not recommended to be used simultaneously with preparations of hydrocortisone, prednisolone or dexamethasone, since in this case the risk of systemic side effects increases in patients.
With the simultaneous use of oral antibiotics tetracycline group should closely monitor the work of the liver, as the risk of side effects increases dramatically.

Special instructions

The drug can not be abruptly abolished. As the skin condition improves, the ointment of Gioxisone should be mixed with a baby or any other cream. Every day, the dose of ointment is reduced, and the dose of the cream is increased, so the effect on the adrenal glands will be minimal.
The active substances of the drug do not have a negative effect on the work of the nervous system and do not inhibit the rate of psychomotor reactions.

Conditions of dispensing and storage of the drug

You don't need a prescription to buy Gioxisone. Keep the drug away from children in a cool dark place at a temperature of not more than 20 degrees. Shelf life of the ointment is 3 years from the date of production, at the end of this period the drug can not be used.