Imunofan supp rectal 0.09mg (90mcg) #5

Instruction for Imunofan

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The drug Imunofan is a drug from the group of immunostimulants, which is prescribed for patients with weakened protective forces of the body.

Form of formulation and composition of the preparation

The preparation of Imunofan is available in the form of suppositories for rectal administration. Candles are packed in contour squares on 5 pieces in a cardboard box. The drug is accompanied by an instruction with a detailed description.
The main active component of the suppositories is arginyl-alpha-aspartyl-lysyl-valyl-tyrosyl-arginine-100 μg in 1 suppository.

Pharmacological properties of the drug

Candles of Imunofan have a pronounced immunostimulating, detoxifying, hepatoprotective effect. The therapeutic effect of the drug is based on the restoration of metabolic processes in the body, stimulation of protective forces, increasing the resistance of the organism to infections.
After the introduction of the suppository into the rectum, the therapeutic effect develops after 2 hours - this is called the fast phase. For 2-3 days, the medications speak of the middle phase. The therapeutic effect from 7 days to 4 months is called a slow phase.
During the fast phase, a detoxification effect is manifested - all decay products are excreted from the body, catalase and lactoferin production is increased. Under the influence of the active component of the drug in the patient, the level of lipids and cholesterol in the blood decreases. In the presence of inflammatory processes in the liver and in violation of its function, the action of the drug prevents cytolysis, reduces the activity of liver transaminases, and also normalizes the level of bilirubin in the blood.
In the middle phase of the drug in the body, stimulation of cellular phagocytosis and destruction of viruses and pathogenic microorganisms inside cells are observed.
The slow phase of the drug starts from 7-10 days after the administration of the suppository and lasts up to 4 months. During this period, the work of the immune system is normalized, the production of specific antibodies increases. The effect of the drug on the production of specific antibodies is akin to vaccination, but unlike the latter, the drug is well tolerated by allergy sufferers. Under the influence of suppositories, some types of tumor cells are suppressed, and sensitivity to cytotoxic drugs in cancer patients increases.

Indications for use

The drug Imunofan is prescribed for adults and children from 2 years to treat and prevent the following conditions:
    Toxic poisoning of the body;
    Chronic inflammatory diseases of internal organs of various genesis;
    Immunodeficiency conditions;
    Frequent viral infections, weakened immunity;
    Against the background of treatment with antitumor drugs as a restoring and immunostimulating agent.

Contraindications

Suppositories can be used only as directed by a doctor. Before starting therapy, the patient should carefully read the enclosed instruction for limitations. Contraindications to the use of Imunofan suppositories are the following conditions:
    Age of children under 2 years;
    Rhesus-conflict in a woman during pregnancy;
    Individual hypersensitivity to the components of the drug.

Dosing and Administration

Suppositories Imunofan intended for introduction into the rectum. A patient receives 1 candle per day.
For the treatment of oncological neoplasms in therapy with chemotherapy, 1 suppository is prescribed once a day for 10 days. If necessary, the treatment is extended for the entire period of chemotherapy or radiotherapy.
Patients with oncological diseases complicated by metastases are prescribed 1 suppository of the drug 10 days before the start of chemotherapy and throughout the subsequent treatment period.
Children with malignant neoplasms are prescribed 1 candle of the drug course for 20-30 days. This helps to avoid toxicosis after radiation or chemotherapy.
At a papilloma of a virus infection at children and adults 1 suppository in day is appointed or nominated. The course of therapy with the drug is 10 days.
With cytomegalovirus, herpes, toxoplasmosis, chlamydia, 1 suppository is prescribed once a day. The duration of the course of therapy is 10 days.
When immunodeficiency patients are prescribed 1 candle daily for 20 days. After this, take a break for 2 weeks, then spend one more course.
With viral hepatitis appoint 1 suppository of the drug 1 time per day for 20 days. In order to prevent recurrence of the disease, the course of therapy is repeated after 2 months.
In septic conditions, surgical patients are prescribed 1 suppository of the drug once a day. The duration of treatment is 15 days.

Use of the drug during pregnancy and lactation

There are no data on the negative effect of the active substance of suppositories on the fetus in pregnant women. Treatment with the drug should be carried out strictly under the supervision of the doctor in the event that the expected benefit for the mother exceeds the potential risk to the fetus. It is not recommended to use candles in the first trimester of pregnancy.
It is not known whether the active substance of the drug penetrates into breast milk, and how it affects the baby's body, so the use of suppositories during breastfeeding is not recommended. If you need therapy, a woman should think about transferring the baby to a formula.

Side effects

In most cases, the drug is well tolerated by patients. After the introduction of the suppository, the patient may complain of a feeling of discomfort in the anus, burning, itching. These phenomena pass independently, without any treatment and do not require the abolition of therapy. In patients with increased individual sensitivity, allergic rashes on the skin may occur.

Overdose

The cases of an overdose of Imunofan were not registered, however, in order to prevent the development of adverse reactions, it is not recommended to exceed the dose specified in the instructions.

Interaction of the drug with other drugs

Suppositories of Imunofan enhance the therapeutic effect of glucocorticosteroids, cytostatics, antiviral drugs, antibiotics, non-steroidal anti-inflammatory drugs.

special instructions

Since under the influence of the drug activated cell phagocytosis, in patients with chronic diseases, exacerbations of pathologies at the beginning of the course of therapy are possible. With the development of this condition, treatment should continue in the same dosage.
The drug does not exert a depressing effect on the central nervous system and does not inhibit the rate of psychomotor reactions.

Conditions of dispensing and storage of the drug

Suppositories are allowed for over-the-counter leave from pharmacies. Store the drug should be in the refrigerator, away from children. Shelf life is 24 months from the date of production. After this period, the medicine can not be used.