Proflosin caps 0.4mg #100

User manual for Proflosin

You can buy Proflosin capsules on this page

Composition

Tamsulosin hydrochloride, microcrystalline cellulose, copolymer of ethyl acrylate and methacrylic acid, triethyl citrate, talc, titanium dioxide, yellow oxide, red oxide, gelatin, indigo carmine.

Form of issue

Capsules of gelatin prolonged action soluble in the intestine, light orange color, in a blister of 10 pieces, cardboard packs No. 10, 30, 100.

pharmachologic effect

Correction of urodynamics, regulation of metabolism in the prostate gland.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The drug binds postsynaptic A-adrenergic receptors, thereby causing relaxation of the smooth muscles of the urethra and prostate.
Pharmacodynamic effect of the drug is determined by the properties of the basic active substance - tamsulosin hydrochloride, which as a result of relaxation of smooth muscles of genitourinary system, significantly increases the flow of urine, kupiruya symptoms of bladder irritation and low urinary tract obstruction. Tamsulosin, by reducing the resistance of peripheral vessels, can lower blood pressure.

Pharmacokinetics

Proflosin is quickly absorbed into the digestive tract, it has high bioavailability. Eating slows down the absorption process. The maximum concentration in the plasma occurs six hours after taking the dose of the drug on a full stomach.
It binds to plasma proteins by 99%. Metabolised in the liver. It is excreted in the urine. The half-life is 10 to 13 hours.

Indications for use

Dysuric disorders in benign prostatic hyperplasia.

Contraindications

Hypersensitivity to the components of the drug, severe hepatic insufficiency, arterial hypotension, orthostatic hypotension, severe chronic renal failure.

Side effects

    Fainting, drowsiness / insomnia, orthostatic hypotension, palpitation, chest pain, tachycardia;
    nausea, constipation / diarrhea, vomiting;
    decreased libido, retrograde ejaculation;
    allergic reactions; asthenia; swelling.
Precautionary measures
Take with care the drivers of vehicles and in the performance of work in which a high concentration of attention is required.

Instructions for Proflosin

Adults once a day for one capsule of Proflosin after breakfast. The capsule must be swallowed whole, without chewing, with a 0.5-1 glass of water. The instruction for use contains a prohibition on the separation of the capsule into parts, since the action of the active substance is inactivated. The course of admission is determined individually.

Overdose

In medical practice cases of overdose were not observed. But theoretically there can be a sharp decline in blood pressure and tachycardia. In such cases it is necessary to carry out activities aimed at restoring blood pressure and heart rate. In order to reduce the absorption of tamsulosin, it is necessary to wash the stomach, take activated charcoal.

Interaction

With concomitant use of Tamsulosin with cimetidine, there is a slight increase in plasma concentrations of tamsulosin; when taken with Furosemide, there is a decrease in concentration, but dose adjustment is not required, when ai-adrenoreceptor blockers are taken, there is a high risk of lowering blood pressure. The rate of excretion of Tamsulosin increases with simultaneous admission with Diclofenac and Warfarin.

Terms of sale

You don't need a prescription to buy Proflosin online.

Storage conditions

In a dry place at a temperature of no higher than 30 ° C.
Shelf life - 3 years.

Reviews of Proflosin

Reviews about Proflosin on the forums of men who have prostate adenoma, in most cases confirm the effectiveness of the drug. Most of them note that problems with urination after taking the drug have decreased or completely disappeared. Some patients complain of a decrease in pressure, a painful erection, a heart palpitations.