Encephabol suspension 80.5mg/5ml 200ml

Encephabol instruction for use

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Composition

5 ml of syrup contains pyrithinol 80.5 mg + methyl parahydroxybenzoate, sodium saccharinate dihydrate, citric acid, propyl parahydroxybenzoate, potassium sorbate, povidone, hydroxyethylcellulose, various natural essences, glycerol, colloidal silicon dioxide, 70% sorbitol solution, water.

Form of issue

Tablets in a yellow shell, round, convex. Cardboard packages of 50 pieces.
Suspension Encephabol viscous, white or almost white, with a specific sweetish odor, in 200 ml vials.

pharmachologic effect

Nootrop.

Pharmacodynamics and pharmacokinetics

The active substance of the preparation pyrithinol has the ability to normalize, metabolic processes occurring in the tissues of the cerebral cortex. In particular, to strengthen the process of glucose uptake and its utilization, the release of acetylcholine from the site of synoptic communication, to normalize the exchange of nucleic acids.
Also, pyrithinol is a strong antioxidant, due to which it has the ability to stabilize the structure of neuronal envelopes. Their functional activity increases, and the probability of damage decreases.
The active substance directly affects the rheolytic properties of the blood. It prevents ischemia in the brain tissues and helps normalize the processes of nutrition and oxygen supply to already damaged areas. The viscosity of the blood decreases, the elasticity and the number of erythrocytes increases.
Thus, Encephabol restores disturbances in the brain tissues, which leads to improved memory and stimulation of mental performance.
Already for an hour, after taking the drug, it reaches its maximum concentration in the blood. Up to half of the active component - pyrithinol binds to plasma proteins. The withdrawal of the drug occurs in the urine, a small amount - with feces, for 2.5 hours.

Indications for use

Treatment and prevention of violations of the processes of thinking and remembering when:
    degenerative dementia of vascular or mixed nature;
    atherosclerosis;
    states after injuries to the head and brain;
    encephalopathy in children;
    cerebral atherosclerosis;
    after encephalitis;
    cerebrosthenic syndrome;
    retarded development of the psyche.

Contraindications

Allergy to pyrithinol.
Use with caution in diseases of the liver and kidneys and autoimmune diseases.

Side effects

    vomiting, decreased appetite, diarrhea, nausea;
    displacement of balance of processes of inhibition and excitation towards the latter, rapid fatigue, insomnia;
    an allergy on the skin in the form of rash and itching.

Instructions for use Encephabol (Method and dosage)

The regimen should be prescribed by the doctor individually.
According to the instructions for Encephabol, the daily dose for an adult is usually 0.6 g per day. That is equivalent to taking two tablets or 10 ml of syrup 3 times a day at regular intervals.
Encephalol regimen for children:
    over 7 years - from 2.5 to 10 ml of suspension or 2 tablets 1-3 times a day;
    from one year to seven - from 2.5 to 5 ml of suspension 1-3 times a day;
    for an infant from two months to a year - 1 ml each every 2 weeks to 5 ml per day;
    for children from three days of life - 1 ml in the morning.
Children are usually prescribed a drug in the form of a suspension.
The medicine is drunk for a long time, up to 2 months after eating.
For newborns, the course can last up to six months.

Overdose

When therapeutic doses are exceeded, side effects can be exacerbated.
There is no specific antidote for pyrithinol, enterosorbents should be taken. Therapy is according to the symptoms.

Interaction

With caution should be combined with penitsillaminom, levomizolom preparations of gold and sulfasalazinom. There may be an increase in side effects.

Storage conditions

It's a dark cool place.
Shelf life - 5 years.

special instructions

It is not recommended for people with intolerance to fructose.
To avoid insomnia, the last dose of the drug is taken no more than 3 hours before bedtime.
Possible violation of psychomotorics when controlling mechanisms.

Analogues of Encephabol

Aminalon, Cavinton forte, nootropil, piracetam, phenibut, ceraxon

In pregnancy and lactation

The degree of penetration through the hemoplacental barrier and into breast milk is quite high. Therefore the question of reception should be decided by the doctor individually for each specific case.

Reviews about Encephabol

Reviews of doctors: Suspension is usually prescribed to children to stimulate speech development, motor skills, concentration and overall development of the child. After the course of the drug, there are improvements in all of these indicators.
Reviews for Encephabol for children: Often assigned to small children, for babies. Those who helped the drug, there is an improvement in memory, stimulation of speech development, resistance to hypoxia. The best results were observed when taking long-term courses.