Noben caps 30mg #30

Noben instruction

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Composition
One capsule, as an active ingredient, contains 30 mg of idebenone.
Additional Ingredients:
    102 mg - lactose monohydrate;
    39.4 mg - potato starch;
    20 mg of microcrystalline cellulose;
    8 mg of povidone;
    0.6 mg magnesium stearate.
Form of issue
The drug Noben is available in the form of capsules, 30 pieces in one package.
pharmachologic effect
Nootropic.
Pharmacodynamics and pharmacokinetics
Idebenon activates the processes of synthesis of ATP and glucose, increases blood supply and volume of incoming oxygen in the brain tissue, thereby improving the metabolic processes taking place in it and facilitating the excretion of lactates. Being an antioxidant, it inhibits lipid peroxidation, thus, preventing damage to the membrane of mitochondria and neurons.
Noben shows a nootropic effect with a parallel neuroprotective and psychostimulating effect. It has antidepressant, psychostimulating and anti-asthenic action since the first days of its application, followed by 20-25 days with a mnemotropic and nootropic effect.
When administered orally, the contents of the Noben capsule are quickly absorbed into the digestive tract. The highest concentration of idebenone in the blood is observed after 4 hours. The active ingredient easily bypasses the BBB and is distributed in significant amounts in the brain tissues. Even with prolonged admission does not cumulate. T1 / 2 approximately - 18 hours. Metabolism occurs in the liver. It is brought to a lesser degree with fecal masses and more with urine.
Indications for use
Indications for the use of the drug Noben are various cerebrostenic disorders of traumatic, vascular, psychogenic (neurasthenia) nature and their combination, which are accompanied by: attention and / or memory impairments, decreased overall activity and intellectual productivity, emotional disorders, asthenic, depressive, astheno-depressive states , dizziness, headaches, noise in the ears.
The effectiveness of Noben is proved in the psychoorganic syndrome, provoked by circulatory disturbances in the brain, as well as by its involutional age-related changes.
Contraindications
    hypersensitivity to idebenon or other ingredients of Noben's capsules;
    renal failure in severe form.
Side effects
    dyspepsia;
    allergic manifestations;
    mental agitation;
    violation of falling asleep;
    headache.
Instruction for the use of Noben
Drug Noben recommended to take inside (oral), preferably after a meal. Typically, the daily dose of idebenone is 60-90 mg, with the first capsule (30 mg) taken 2 or 3 times a day. Patients are advised to distribute the reception of capsules in such a way as to conduct the last reception up to 17 hours, in order to prevent problems of falling asleep associated with possible increased excitement.
The duration of Noben's intake is usually from 1.5 to 2 months. Based on the severity of the disease and the severity of symptoms, it is recommended that 2-3 courses of treatment be administered for 12 months.
Overdose
In the case of taking elevated doses of idebenone, there may be an increase in its side effects.
In this case, the use of usual, in such circumstances, measures to prevent complications, including gastric lavage, intake of absorbents (activated charcoal), and symptomatic therapy is indicated.
Interaction
At this time Noben's interaction with other drugs is not established.
Storage conditions
Capsules are stored in the manufacturer's packaging, in a dark place inaccessible to children, at ambient temperatures up to 30 ° C.
Shelf life - 36 months.
special instructions
If it is necessary to conduct accurate or dangerous works, as well as driving transport, it is forbidden to take Noben.
Children
The decision to apply Noben in childhood is taken exclusively by the pediatrician, given the evidence and all possible risks.
With alcohol
Do not recommend the combination of taking idebenon and alcoholic beverages.
During pregnancy (and lactation)
The periods of breastfeeding and pregnancy are contraindications to the use of Noben's capsules.
Reviews of Noben
Virtually all the reviews about Noben at the forums are extremely positive. It is very rare to find disapproval statements about this drug, and those are related not to the effectiveness of its action, but to the problem of falling asleep and increased excitability, which may be due to the use of high doses of idebenone or the reception of capsules in the evening.
In other respects, the effectiveness, speed of action and the absence of adverse drug reactions, in the treatment of a variety of neurological diseases, cerebrovascular disorders, depressions, emotional disorders, and others, are confirmed by the experience of applying Noben to a multitude of patients. Also, the approval of the idebenon for intellectual activity, increasing attention and improving memory.
It is worth recalling that it is impossible to independently prescribe any medications, and even more so, preparations of nootropic action. For successful therapy should always consult with a specialist who will choose an appropriate drug for your condition and prescribe the appropriate course of treatment.