Fluimucil solution 10% 3ml #5

Fluimucil instruction

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Composition

1 ml solution for inhalation and injection contains 100 mg of acetylcysteine, in 1 ampoule - 300 mg of acetylcysteine, additional substances: sodium hydroxide, disodium edetate, water.

Form of issue

A solution in glass ampoules of dark color of 3 ml.

pharmachologic effect

Has mucolytic effect. Acetylcysteine ​​ruptures disulfide bonds in mucopolysaccharides of sputum, thereby ensuring its liquefaction and facilitation of excretion. Even in the case of purulent sputum, it remains effective.
The drug prevents the adhesion of bacteria on the epithelium of bronchial mucosa, stimulates cells that synthesize substances that break down fibrin filaments. The same effect of acetylcysteine ​​has on the secret of the mucous upper respiratory tract.
The drug provides an antioxidant effect, has a cytoprotective effect and neutralizes toxins.
Acetylcysteine ​​has an anti-inflammatory effect due to the property of suppressing the formation of free radicals that cause the development of inflammation in the lung tissue.

Pharmacodynamics and pharmacokinetics

After taking the drug, the maximum concentration in the blood occurs within 1-3 hours. Bioavailability of about 10%. Penetrates into the lungs, bronchial secretions, liver and kidneys; through the placenta.
It is excreted in urine, half-life is 1 hour, with cirrhosis of the liver is 8 hours.

Indications for use

    labored expectoration of sputum in respiratory disease (laryngotracheitis, tracheitis, bronchitis, pneumonia, bronchiolitis, lung abscess, pulmonary emphysema, cystic fibrosis, bronchiectasis, atelectasis, which is caused by obstruction of bronchi mucous plug);
    otitis, sinusitis (catarrhal and purulent);
    facilitating the secretion of a viscous secretion from the respiratory system (post-traumatic and postoperative conditions);
    lavage of the nasal passages, middle ear, sinuses, abscesses, fistula, the treatment intervention zone during operations on the mastoid or nasal cavity;
    preparation for aspiration drainage, bronchography, bronchoscopy.

Contraindications

    exacerbation of stomach and duodenum ulcers;
    individual intolerance to acetylcysteine;
    the period of breastfeeding;
    for granules - children under two years;
    for effervescent tablets - children and adolescents under 18 years.
Admission of a solution prepared from granules to children under 2 years is allowed under the supervision of the doctor for life.
In gastric ulcer, hemoptysis, asthma, hypertension, pulmonary hemorrhage, phenylketonuria, renal and hepatic failure, variceal used cautiously.
Intravenous administration of the drug to children under 1 year of age is carried out according to vital indications, under the supervision of a doctor.

Side effects

The digestive system: nausea, vomiting, heartburn, heaviness in the stomach, diarrhea.
Allergic reactions: there may be cases of bronchospasm, urticaria, skin itching.
Of the other symptoms can be very rare: tinnitus, nosebleeds, collapse.
In the case of aerosol: irritating to the respiratory tract, cough reflex character, rhinorrhea, rarely - bronchospasm.
Intramuscular administration can lead to urticaria, burning sensation at the injection site, in the case of prolonged use - dysfunction of kidney and liver.

Instructions for use Fluimucil (Method and dosage)

For adults use inside tablets effervescent - 1 tablet (600 mg) per day once, previously dissolved in a third of a glass of water.
Granules are used for adults and children, dissolving in water (one-third of the glass).
Dosage:
    children over 6 years of age and adults - 600 mg per day in 3 divided doses;
    for children 2 to 6 years, 200 mg twice a day;
    1 - 2 years - 100 mg twice a day.
For newborns, the drug is used under the supervision of a specialist for vital signs, observing a dose of 10 mg / kg of the child's weight. Children in the first year of life are given a syrup from a spoon or a bottle.
The average course of treatment is 5-10 days for acute course, and several months for chronic.
For inhalations in physiotherapy use a 10% solution in an amount of 3-9 ml. Duration of inhalations up to 20 minutes, from 2 to 4 times a day.
In the case of using the drug for bronchoscopy for therapeutic purposes, 1-2 ampoules are used to flush the bronchi.
In the external ear canal is instilled in a dose of up to 300 mg per dose.
For use in rhinitis, there is a special form - a drop in the nose.
When administered intravenously (drip or blast slowly) or intramuscularly, the doses are determined as follows:
    adults - 300 mg to 2 times a day;
    children 6-14 years old on 150 mg 2 r / day;
    Children under 6 years - at a rate of 10 mg / kg.
Children under the age of 1 year are injected with acetylcysteine ​​under steady-state conditions according to vital indications.
The duration of treatment depends on the patient's condition.
In the case of cough for children under 6 years of age, oral administration should be preferred.
For intravenous administration, the drug is diluted with 0.9% sodium chloride solution in equal amounts. The duration of treatment in the case of intravenous administration should not exceed 10 days.
In elderly patients, the instruction for Fluimucil indicates the need to apply minimum effective doses.

Overdose

Acceptance of the drug in an amount of 0.5 g. per kg of weight per day does not cause an overdose.

Interaction

Joint reception with cough suppressants, which suppress the cough reflex, contribute to sputum stagnation.
The use of tetracyclines (except doxycycline), amphotericin and ampicillin leads to a decrease in the effect of both antibiotics and acetylcysteine, so a break between taking these groups of drugs should be at least 2 hours.
Antiaggregant and vasodilating effect of nitroglycerin is enhanced by simultaneous reception with Fluimucil.
Acetylcysteine ​​can reduce the toxic effect of paracetamol on the liver.
With other medicinal solutions incompatible pharmaceutically.

Terms of sale

You don't need a prescription to buy Fluimucil.
Storage conditions
Away from children, the storage temperature is not more than 25 ° C.
Shelf life - 5 years.

special instructions

Fluimucil is prescribed for patients with bronchial asthma and obstructive bronchitis with caution and under constant control of bronchial patency.
It is not recommended to use in patients with phenylketonuria, since the drug contains aspartame.
To dissolve use only glass containers and do not allow contact with rubber and metal surfaces.
The smell of sulfur that occurs when you open a bag of granules is the usual odor inherent in the active substance.

Fluimucil or ACC - which is better?

Both preparations contain the same active substance. Differ only the manufacturer and the price, and even that is insignificant.

Children

Apply according to the indications according to the instructions for the drug.

In pregnancy and lactation

If there is a need to use the drug in pregnancy, you need to evaluate the ratio of benefits for the mother and the risk to the fetus.
In the period of breastfeeding, when the need for the drug is used, feeding should be discontinued.

Reviews about Fluimucil

Fluimucil is quite popular for use from cough. Numerous reviews, as a rule, are positive. There are good results from coughing - Fluimucil is quite effective in both adults and children. At forums of young mums at the request to recommend a good syrup from a cough many recollect it Флуимуцил. Perhaps the only drawback of using the drug is the formation of large amounts of sputum.
Also, drops in the nose are popular - many positive reviews when used in the case of rhinitis.