ACC 200 tabs #20

ACC 200 instruction for use

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Composition

The drug ACC 200 includes the active ingredient acetylcysteine ​​(200 mg), as well as additional components: sodium bicarbonate, citric acid anhydride, ascorbic acid, mannitol, sodium citrate, saccharin, lactose anhydride, flavor.

Form of issue

ACC 200 is produced in effervescent tablets, white, round flat, on the one hand - risky. Enjoy the aroma of blackberry. Contained in packages of 4, 20, 25 pcs.

pharmachologic effect

It has a mucolytic effect. In view of the fact that there is acetylcysteine ​​of sulfhydryl groups in the structure of the molecule, disulfide bonds of acid mucopolysaccharides of sputum are broken. Due to this process, the viscosity of the mucus is reduced. ACC 200 demonstrates activity also in patients with purulent sputum.
If acetylcysteine ​​is used for prophylactic purposes, in patients who suffer from cystic fibrosis and chronic bronchitis, the severity and frequency of exacerbations decrease.

Pharmacokinetics and pharmacodynamics

After internal administration, the drug is rapidly absorbed. Metabolism, in which a metabolite is formed - cysteine ​​and other metabolites, passes in the human liver.
Bioavailability at internal reception makes 10%, communication with fibers of plasma - on 50%. In the blood, the greatest concentration is observed after 1-3 hours. It is excreted in urine, half-life is 1 hour.

Indications for use

Application of ACC 200 is shown in such cases:
    with diseases of the respiratory system, if there is a formation of viscous sputum, which is difficult to separate (laryngotracheitis, bronchitis acute, chronic, obstructive, bronchiectasis, cystic fibrosis, pneumonia, bronchial asthma, bronchiolitis);
    otitis media;
    sinusitis is acute and chronic.

Contraindications

it is contraindicated to take the pill in the following cases:
    high sensitivity to acetylcysteine ​​or other ingredients of drugs;
    period of exacerbation of stomach and duodenum ulcers;
    pulmonary hemorrhage;
    hemoptysis;
    pregnancy and feeding;
    lactose intolerance, lack of lactase;
    glucose-galactose malabsorption;
    the child's age is up to 2 years.
Carefully apply this medication with an ulcer of the duodenum and stomach in an anamnesis, with intolerance to histamine. Also cautiously prescribed medicine for people with bronchial asthma, varicose veins of the esophagus, obstructive bronchitis, adrenal diseases, hepatic and renal insufficiency, arterial hypertension.

Side effects

These side effects may occur during the administration of the drug:
    nervous system: tinnitus, headache;
    cardiovascular system: lowering of arterial pressure, tachycardia;
    digestion: diarrhea, nausea, vomiting, stomatitis;
    allergic reactions: single manifestations - bronchospasm, urticaria, pruritus, rash on the skin;
    other reactions: single manifestations - bleeding.

Effervescent tablets ACC 200, instructions for use (Method and dosage)

Instructions for use ACC 200 provides that the drug, like the powder, prescribed to patients after 14 years of 200 mg two or three times a day.
Patients from 6 to 14 years of age use 1 tablet twice a day.
Children aged 2 to 5 years should take half the tablets of ACC 200 two or three times a day.
The patient with cystic fibrosis after 6 years shows the intake of 1 table. 3 times a day, children up to 6 years are prescribed a drug at the rate of 400 mg of acetylcysteine ​​per day. If the patient's weight exceeds 30 kg, the dose, if necessary, is increased to 800 mg per day.
If the catarrhal diseases are treated, the course of admission lasts 5-7 days.
Before taking the medicine, and after that, one must drink plenty of fluids to strengthen the mucolytic action of the drug. It is necessary to drink the drug after eating.
The method of diluting the tablets is the same as the way the powder is used. They need to be dissolved in half a cup of water, the solution immediately drink.

Overdose

If an overdose has occurred, nausea, stomach pain, heartburn, and diarrhea may occur. Dangerous and severe manifestations have not been reported so far.

Interaction

It should be borne in mind that with the simultaneous administration of ACC 200 and other cough suppressants, it is possible to develop a dangerous stagnation of mucus due to the fact that the cough reflex is suppressed. Therefore, such medications should be combined carefully.
Acetylcysteine ​​can enhance the vasodilator effect of nitroglycerin if taken at the same time.
Synergism of acetylcysteine ​​with bronchodilators is observed.
Acetylcysteine ​​does not combine pharmaceutically with antibiotics (penicillins, cephalosporins, Amphotericin B, Erythromycin, Tetracycline) and proteolytic enzymes.
With simultaneous intake of acetylcysteine ​​reduces the absorption of tetracycline, cephalosporins, penicillins. Therefore, it is necessary to take such drugs with an interval of not less than two hours.
If acetylcysteine ​​is in contact with rubber, metals, sulphides with characteristic odor are formed.

Terms of sale

ACC 200 can be bought without a prescription.

Storage conditions

Keep away from children, from ingress of moisture and light, store at a temperature of not more than 30 degrees. Close the tube tightly after removing the tablet.
Shelf life - 3 years.

special instructions

If ACC 200 is prescribed for patients with bronchial asthma and bronchitis obstructive, it is necessary to do this carefully and constantly monitor bronchial patency.
If any side effects develop, you need to stop treatment and consult a doctor.
If necessary, dissolve the drug should use glassware.
Doctors do not recommend taking the drug before bed. It is advisable to do this until 18 hours.
Patients with diabetes should take into account that in the ACC 200 there is sucrose.
It does not affect the ability to concentrate attention, drive vehicles.

Children

It is not assigned to children until they reach the age of two.

In pregnancy and lactation

Since there is no clear data on the effect of the drug during pregnancy, it is not prescribed during pregnancy, but also during lactation.

Reviews about ACC 200

Most reviews on the network are positive, as users write about the effectiveness of this medication. Feedback from the ACC 200 testifies that the medicine, in a few receptions, facilitates the symptoms, promotes active sputum discharge in diseases of the respiratory system. It is noted that it is convenient to use. Very rarely there is mention of the development of minor negative phenomena.