ACC 100 tabs 100mg #20

Instruction for ACC 100

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Composition

The drug ACC 100 includes the active ingredient acetylcysteine ​​(100 mg) and other auxiliary ingredients: anhydrous citric acid, sodium hydrogen carbonate, anhydrous lactose, anhydrous sodium carbonate, sodium saccharinate, mannitol, sodium citrate, ascorbic acid, flavor.

Form of issue

ACC 100 is produced in the form of effervescent tablets. They are flat-cylindrical, round, white in color. Enjoy the aroma of blackberry. There may be a faint smell of sulfur. After dilution, a solution is obtained without color, transparent. It has the smell of blackberry, may have a slight sulfur flavor.

pharmachologic effect

The substance acetylcysteine ​​is a derivative of the amino acid cysteine. The mucolytic effect of this substance on the body is noted. Under its influence, the process of sputum evacuation is facilitated, since acetylcysteine ​​acts directly on phlegm, in particular, on its rheological properties. As a consequence, the viscosity of phlegm decreases. The drug also provides an antioxidant effect, protecting cells from free radical oxidation, which occurs during severe inflammatory reactions. It is active if the patient separates purulent sputum.
Under the influence of acetylcysteine, the synthesis of glutathione, which is an important component of chemical detoxification, as well as an antioxidant system, is improved.
If acetylcysteine ​​is used for the prevention, then people suffering from cystic fibrosis and bronchitis chronic, the severity and frequency of exacerbations of bacterial origin decreases.

Pharmacokinetics and pharmacodynamics

There is a high level of absorption. Metabolism occurs in the liver, with the formation of an active metabolite - cysteine, as well as other metabolites. Level of bioavailability - 10%, communication with blood proteins - 50%. The greatest concentration is noted in the body after 1-3 hours. It is excreted through the kidneys, the half-life is about 1 hour.

Indications for use

The application of ACC 100 is shown in such cases:
    diseases of the respiratory system, which form viscous sputum, which is difficult to separate, (acute bronchitis, chronic and obstructive bronchial asthma, laryngotracheitis, tracheitis, lung abscess, pneumonia, bronchiectasis, bronchiolitis);
    cystic fibrosis;
    sinusitis acute and chronic;
    COPD;
    otitis media.

Contraindications

Assign ACC 100 in such cases:
    hypersensitivity to acetylcysteine ​​or to any other ingredients of the drug;
    hemoptysis;
    bleeding pulmonary;
    exacerbation of peptic ulcer;
    pregnancy and breastfeeding;
    glucose-galactose malabsorption;
    lack of lactase, lactose intolerance;
    the child's age is up to 2 years.
It is necessary to apply ACC 100 carefully with duodenal ulcer and stomach history, in case of histamine intolerance, with bronchial asthma, esophageal varices, adrenal diseases, obstructive bronchitis, hepatic and renal insufficiency, arterial hypertension.

Side effects

Probably a number of side effects when using this tool:
    manifestations of allergies: a rash, itching of the skin, hives, exanthema, angioedema, tachycardia, lowering of blood pressure; in very rare cases - Stevens-Johnson syndrome, anaphylactic manifestations, toxic epidermal necrolysis;
    system respiratory: in rare cases - bronchospasm, dyspnea;
    Gastrointestinal system: abdominal pain, heartburn, diarrhea, vomiting, nausea, stomatitis, dyspepsia;
    sensory organs: noise in the ears;
    other manifestations: fever, headache; in isolated cases - bleeding.

Effervescent tablets ACC 100, instructions for use (Method and dosage)

Instructions for use ACC 100 provides that the drug 100 mg should be used orally after eating.
Patients after 14 years of age - 2 tablets. 2-3 times a day.
Children and adolescents from 6 to 14 years old are shown taking 1 table. 3 times a day or 2 tablets. 2 times a day.
The instruction for ACC 100 for children from 2 to 6 years is 1 table. 2-3 times a day.
Patients with cystic fibrosis, whose weight is more than 30 kg, if necessary, increase the dose to 800 mg of acetylcysteine ​​per day.
Tablets of 100 mg are dissolved in 1 glass of liquid, you need to take the solution immediately.

Overdose

When an overdose of the drug can cause nausea, pain in the stomach, heartburn, diarrhea. There were no dangerous side effects in overdose.

Interaction

If ACC 100 is taken with other cough suppressants, mucus congestion may develop due to suppression of the cough reflex. It is necessary to practice with caution such a combination of drugs.
Acetylcysteine ​​enhances the vasodilating effect of nitroglycerin, provided that these drugs are taken at the same time.
Pharmaceutically, acetylcysteine ​​is not combined with antibiotics (cephalosporins, penicillins, amphotericin B, tetracycline, erythromycin) and proteolytic enzymes.
With the simultaneous use of acetylcysteine ​​reduces the absorption of cephalosporins, tetracycline, penicillins. It is necessary to adhere to the interval of not less than two hours between the methods of these medicines.
In the case of contact of acetylcysteine ​​with metals, rubber, etc., sulphides are formed.

Terms of sale

You can buy ACC 100 without a prescription.

Storage conditions

It should be stored at a temperature of not more than 30 degrees, protected from children, from moisture and light.
Shelf life - 3 years.

special instructions

It is important to use glassware when diluting the drug to avoid contact with rubber, substances that are easily ignited by metals.
In very rare cases, when taking acetylcysteine, severe allergic reactions were noted. If changes in skin and mucous membranes are noted, it is necessary to consult a doctor immediately stopping taking.
Caution should be taken ACC 100 people who suffer from obstructive bronchitis and bronchial asthma, while it is important to constantly monitor bronchial patency.
It is not recommended to take ACC 100 at bedtime, preferably before 18:00.
The ability of a person to work with dangerous mechanisms, drive transport is not affected.

ACC 100 for children

The instruction indicates that the medicine should not be administered to children under two years of age. It is important for parents to consider all the doctor's recommendations. You should consider how to dilute the ACC 100 for children, and adhere to the prescribed dosage.

In pregnancy and lactation

There is no data on the effect of the drug during pregnancy, therefore, during this period, as well as with breastfeeding, ACC 100 is not prescribed.

Reviews

Parents write that ACC 100 is an effective drug and helps to quickly relieve the condition and provide active coughing up phlegm. Users note that the drug is effective in bronchitis, otitis media, pneumonia and other diseases. Side effects, according to those who leave feedback on the network, are rare.