Tyzine Xylo 0.05% 10ml

Instruction for Tyzine Xylo

You can buy Tyzine Xylo here

The drug Tyzine Xylo belongs to the group of vasoconstrictive nasal agents, which is widely used in otolaryngology.

Form of issue and composition

The drug Tysin xylo is available in the form of a spray for spraying into the nasal passages of 0.05% and 0.1%. The preparation is packed in a bottle of dark glass with a volume of 10 ml, equipped with a nozzle-sprayer with a metering device. The bottle with the drug is packed in a cardboard box with the attached detailed instructions.
The contents of the vial is a clear, colorless solution with a weak specific odor, the main substance of which is Xylometazoline hydrochloride (in 1 ml of the preparation contains 500 μg or 1 mg of active substance, respectively).
Also, the preparation contains auxiliary components: benzalkonium chloride, sorbitol, sodium chloride, purified water and others.

Indications for use

Spray Tyzine Xylo is prescribed for patients to be sprayed into the nasal passages as a symptomatic agent in the common cold and inflammation of the nasal mucosa of various genesis, namely:
    allergic rhinitis;
    rhinitis on the background of ARVI;
    sinusitis;
    sinusitis;
    rhinorrhea;
    Pollinosis;
    otitis media;
    before preparing the patient for diagnostic procedures in the nasal passages.

Contraindications

The drug has some contraindications and serious limitations, so it is important to carefully read the attached instructions before using the spray. The drug can not be used in the following conditions:
    arterial hypertension;
    cardiopalmus;
    simultaneous treatment with drugs from the MAO inhibitor group;
    atherosclerotic plaques on the walls of blood vessels;
    increased intraocular pressure;
    atrophic rhinitis;
    polyps in the nasal cavity;
    the transferred surgical interventions on the meninges;
    the age of children under 6 years (for a spray dosage of 0.1%);
    the age of children under 2 years (for a spray dosage of 0.05%);
    individual intolerance of the drug components.
Relative contraindications (the drug can be used with caution and under the supervision of a doctor) are:
    cardiac ischemia;
    thyrotoxicosis;
    diabetes;
    pheochromocytoma;
    hyperplasia of the prostate.

Dosing and Administration

The drug Tyzine Xylo Spray is intended for intranasal spraying. One click equals one dose of the drug. Children aged 2 to 6 years should use a spray with a dosage of 0.05%, spray the drug 1-2 times a day, one push into each nostril.
Children from 6 years and adults are prescribed Tyzine Xylo dosage 0.1%, spray the drug into each nasal passage 1-2 times a day. The duration of treatment with the drug should not exceed 5-7 days, since in this case the risk of side effects increases.
In the absence of the desired therapeutic effect or, conversely, the worsening of the condition, the patient should consult a doctor for advice, perhaps the treatment was not properly prescribed.

Use of the drug during pregnancy and during breastfeeding

Despite the fact that the active active substance Tyzine Xylo spray acts locally, a small dose of it is still absorbed into the systemic bloodstream. Penetrating to the vessels of the placenta, the drug contributes to their narrowing, respectively, the fetus receives an insufficient amount of oxygen. Given this information, the use of Tyzine Xylo spray during child-bearing is not recommended for women. In severe cases, treatment with the drug is only possible when the expected benefit to the mother exceeds the potential risks to the fetus. In the course of clinical trials, no embryotoxic or teratogenic effects of the drug on the fetus have been established.
It is not known whether Xylometazoline can be excreted in breast milk, and how it can affect the baby, so the drug is not prescribed for the treatment of rhinitis in nursing mothers. When a woman needs therapy, it is recommended to stop lactation.

Adverse Events

Usually the drug is tolerated very well by patients, but in individuals with increased individual sensitivity to Xylometazoline, side effects may occur:
    burning in the nose;
    constant sneezing;
    itching in the nose;
    increased excretion from the nose;
    swelling of the mucous membranes;
    development of addiction and addiction to the drug;
    development of drug rhinitis;
    atrophy of the mucous membranes of the nose;
    nasal bleeding.
To avoid the development of such side effects, do not use the drug for more than 7 days and exceed the daily dose specified in the instructions.

Overdose

With long-term use of Tyzine Xylo spray, the patient develops signs of an overdose, which is expressed in the form of increased local side effects and systemic reactions:
    dizziness and headache;
    drowsiness;
    depression;
    tachycardia;
    increased blood pressure;
    impaired vision;
    addiction and dependence on the drug.
In case of signs of overdose, the patient should stop using the spray and consult a doctor. If necessary, the patient is symptomatically treated.

Interaction of the drug with other drugs

The drug Tyzine Xylo in the form of a spray can not be administered to patients simultaneously with MAO inhibitors and tricyclic antidepressants. This drug interaction causes an increase in blood pressure.
It is not recommended to combine the drug with other nasal vasoconstrictor drops due to an increased risk of side effects.

special instructions

Before using the drug, the patient should clear the nose of accumulated mucus and crusts.
Prolonged use of Tysin Xylo can lead to atrophic changes in the nasal mucosa, which should be taken into account and do not use the spray for more than 7 days.
In patients with chronic rhinitis, the drug should be alternated with other intranasal drops, the active ingredient of which is not Xylometazoline.
Since the hypersensitive patients may experience drowsiness and dizziness, it is necessary to abstain during therapy from driving a car and controlling complex equipment that requires increased concentration of attention.
A drug with a dosage of 0.1% is forbidden to use for the treatment of rhinitis in children younger than 6 years, as this in most cases leads to severe side effects from the cardiovascular system.
Experience with Tisin Xylo spray application at a dosage of 0.05% in children under 2 years is not available, so it is not recommended to use the drug in pediatric practice for patients younger than 2 years without consulting a doctor.

Leave and storage conditions

Spray Tyzine Xylo can be purchased from pharmacies without a doctor's prescription. Keep the bottle with the drug recommended away from sunlight, in a dry, cool, inaccessible place for children. Shelf life is 3 years from the date of manufacture, indicated on the package.