Loperamide 2mg #20

Loperamide user manual

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Loperamide is a drug that is prescribed to patients for the rapid elimination of an intestinal disorder, in particular diarrhea.

Form of formulation and composition of the preparation

Loperamide is available in the form of tablets for oral administration in white in blister packs of 10 in a cardboard box. The box contains a detailed instruction with a description.
Each tablet contains 2 mg of active active ingredient - Loperamide hydrochloride, as well as a number of auxiliary chemicals.

Pharmacological properties of the drug

Loperamide is an antidiarrhoeic remedy. When the pill is taken inside, the active ingredient acts directly in the walls of the intestine, reducing its motility and provoking the release of prostaglandins - substances that relax smooth muscle. Under the influence of the drug, the time interval for the movement of intestinal contents into the rectum increases, flatulence, swelling and spasmodic pains are eliminated.
In addition to its main therapeutic effect, the drug increases the tone of the anal sphincter. The duration of the drug remains up to 6 hours.

Indications for use

Loperamide tablets are prescribed for patients for the symptomatic treatment of diarrhea of ​​various origins - emotional, drug, arising on the background of radiation therapy or eating a large number of products with laxative effect (apricot, plums, beets).
In addition, loperamide is effective in regulating intestinal work in patients with ileostomy.

Contraindications

Before using the tablets inside, it is recommended to carefully study the accompanying instructions, as Loperamide has some contraindications for use:
    Bowel obstruction or suspicion of it;
    Intestinal bleeding of unexplained etiology;
    Acute dysentery (as a means for monotherapy);
    Individual intolerance to the drug;
    Acute ulcerative colitis;
    Constipation;
    Age in children under 4 years;
    1 trimester of pregnancy.
With caution, the drug can be used in women in the 2nd and 3rd trimester of pregnancy and nursing mothers.

Dosing and Administration

Loperamide tablets are taken orally regardless of food intake. According to the instructions, patients older than 14 years of age, the initial dose of the drug for acute diarrhea is 2 tablets, then, if necessary, take 1 tablet after each liquid stool. The maximum daily dose should not exceed 6 tablets.
For children from 4 years for the treatment of diarrhea appoint ½ tablet of the drug no more than 4 times a day after each liquid emptying.
The duration of treatment with the drug depends on the patient's condition and duration of diarrhea, but in general this period should not exceed 5 days. In the absence of the expected therapeutic effect, the patient is recommended to consult a gastroenterologist to find out the cause of diarrhea and correct treatment.

Use during pregnancy and breastfeeding

Loperamide tablets are contraindicated for use in women in the first trimester of pregnancy because of unproven safety and lack of clinical trials regarding the effect of the drug on intrauterine development of the fetus.
The use in the 2nd and 3rd trimesters of pregnancy is possible only for life indications with a significant excess of the expected benefit for the future mother, in comparison with the possible negative consequences for the fetus.
If you need to use the drug during breastfeeding, the patient is advised to consult a specialist. Since there is no data on the possibility of Loperamide hydrochloride with breastmilk absent, it is better for the nursing mother to transfer the infant to artificial formula with a milk formula when treating with a drug.

Adverse Events

In rare cases, when using Loperamide in patients with hypersensitivity to loperamide hydrochloride, the following side effects developed:
    On the part of the digestive tract organs - abdominal pains, increased gas formation, nausea, constipation, dry mouth, sometimes vomiting is possible;
    From the nervous system - lethargy, fast fatigue, drowsiness, dizziness;
    Allergic reactions - urticaria, rashes on the skin, in very rare cases development of angioedema, with individual intolerance.

Overdose

When ingesting large doses of loperamide, the patient develops an overdose that manifests itself in the following clinical symptoms:
    Bloating, nausea, severe pain in the intestines, a feeling of heaviness in the stomach;
    Constipation;
    Lethargy, drowsiness, apathy, dizziness.
The specific antidote of Loperamide is Naloxone. When developing an overdose, the patient is recommended to wash the stomach and give an antidote.

Interaction with other drugs

With the simultaneous use of the drug with Kolestyraminom, the effectiveness of Loperamide can be reduced.
The simultaneous use of antacid preparations and activated carbon can lead to a less prolonged and pronounced effect of Loperamide tablets.

special instructions

Patients with severe hepatic impairment should be treated with Loperamide only under the supervision of a physician.
Patients younger than 4 years of this drug are not prescribed because of a lack of clinical experience in younger preschool age.

Analogues of tablets against diarrhea Loperamide

Similar in its therapeutic effect to Loperamide tablets are the following:
    Imodium;
    Lopedium;
Before using one of these drugs to treat diarrhea, you should consult a doctor, as they all have a number of certain limitations, contraindications and a different dosage.

Conditions of storage and leave

The drug can be bought freely in a pharmacy without a prescription. Tablets should be kept away from children in a dark, dry, cool place. The shelf life of the drug is indicated on the package, at the end of the drug can not be taken inside.