Termicon spray 1% 30ml

User manual for Termicon

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Composition

Tablets Termicon contain an active ingredient - terbinafine.
Excipients: hypromellose, sodium starch glycolate, milk sugar, MCC, magnesium stearate, aerosil.
Spray Termikon includes in its composition: terbinafine hydrochloride.
Excipients: proksanol 268, ethanol, propylene glycol, water prepared.
The cream contains terbinafine hydrochloride.
Excipients: sodium hydroxide, phenylcarbinol, cetyl palmitate, octadecyl alcohol, sorbitan monostearate, ethyl, isopropyl myristate, polysorbate 60, water prepared.

Form of issue

The drug is produced in several forms: tablets - 7.14 and 28 pieces per pack, spray (15 and 30 grams) and cream (15 grams).

pharmachologic effect

Termicon has fungistatic, fungicidal and antifungal action.

Pharmacodynamics and pharmacokinetics

Terbinafine affects the processes of the fungal cell, causing the inhibition of squalene epoxidase, which is an enzyme of the fungus, promoting the synthesis of ergosterol. This leads to a loss of enzyme activity, suppression of the synthesis of the basic substance of the membrane of the fungal cell. The action of Termicon is directed to microorganisms sensitive to it fungicidally, since it has a wide spectrum of antifungal effect. Sensitivity to this drug is manifested by: Epidermophyton floccosum, which is the causative agent of epidermophytosis, Microsporum canis, a known agent of mycosporia, Trichophyton spp., Which excites trichophytosis, as well as dermatophytes, aspergillas, scopularyopsis, candida, cadaveria and pink lichen.

Indications for use

The drug in the form of tablets is prescribed only in severe cases, and also when the previous therapy with the use of external agents has proved ineffective.
Tablets are recommended for treatment:
    Trichophytia;
    inguinal epidermophyte;
    microsporium;
    onychomycosis;
    candidiasis of skin and mucous membranes;
    dermatomycosis of the skin with a complicated course.
Indications for the use of cream and spray are:
    mycosis stop;
    colored lichen;
    inguinal epidermophytia of light form;
    fungal lesions of smooth skin and certain parts of the body;
    risk of infection with certain fungi - for the purpose of prevention.

Contraindications for use

It is not recommended to apply the Termicon when:
    lactation, pregnancy;
    fungal lesions in children less than 3 years old, weighing up to 20 kg;
    sensitivity to the drug.
During treatment, care should be taken in patients with:
    hepatic insufficiency;
    alcoholism;
    renal insufficiency;
    tumors;
    pathologies of the bone marrow, depressing hematopoiesis;
    metabolic disorders;
    diseases with occlusion of the vessels of the extremities.

Side effects

In the treatment with Termicon, abnormalities such as anorexia, agranulocytosis, dyspepsia, myalgia, diarrhea, arthralgia, nausea, urticaria, stomach pain, thrombocytopenia, rash, taste change, Lyell's syndrome, neutropenia, cholestatic jaundice can occur.

Instructions for use Termicon (Method and dosage)

As the instruction on the use of tablets shows, standard dosages can be half or an entire tablet taken once a day. The treatment can last for 1-12 weeks. Take medicine after eating.
The duration of treatment directly depends on the disorder, for example, with interdigital dermatomycosis it can reach 4-6 weeks, plantar dermatomycosis - 2 weeks; mycosis of the head - 4 weeks and so on.
Cream and spray are for external use. These drugs may be applied to affected areas and surrounding tissues. Ointment is spread in a thin layer and gently rubbed. Spray pre-spray and then lightly rub. External forms are recommended for use every day 1-2 times. Before use, the skin is well dried and cleaned. The course of treatment is 4 weeks. On average, the treatment of torso or shin dermatomycosis, multi-colored lichen, dermatomycosis of the feet is carried out for 7 days.

Overdose

In cases of overdose Termicon may occur: nausea, colic, dizziness, epigastric pain. In this case, symptomatic therapy is performed.

Interaction

Simultaneous application of the Termicon can slow the metabolism of desipramine, antidepressants of the tricyclic structure, fluvoxamine, metoprolol, propaphenone, flecainide, propranolol, chlorpromazine and haloperidol, and reduce the terbinafine clearance. MAO inhibitors increase the elimination of terbinafine.
The inhibition of biotransformation of terbinafine and an increase in its plasma concentration are noted in combination with histamine receptor antagonists. The combination with rifampicin 2 times accelerates the excretion of terbinafine, and cimetidine, on the contrary, slows down.
Simultaneous application of Termicon with oral contraceptives often causes menstrual irregularities. The combination with hepatotoxic drugs increases mutual toxicity, directed at the activity and condition of the liver.

Terms of sale

You don't need a prescription to buy Termicon.

Storage conditions

To store the Termicon, a dark place is intended, well protected from children, at temperatures up to 30 ° C.
Shelf life - 2 years.

Alcohol

At the time of Termicon, alcohol consumption is strictly prohibited.

Reviews of Termicon

Basically, reviews about Termicon tablets are associated with the treatment of complicated mycosis of the skin of the feet or multi-colored lichen. Indeed, therapy with this form of the drug is prescribed when external means have not brought the desired effect.
There are also reviews on Termicon spray, in which the patient told about his use during the treatment of candidiasis. From this message, it becomes clear that timely treatment started with the mandatory observance of personal hygiene rules, the use of additional funds can quickly eliminate this violation.
In addition, as testimonials on Termicon ointment show, this drug is actively used in the treatment of various fungal lesions. It has been established that at the initial stage the Termicon ointment exhibits the highest activity.
As is known, fungal diseases are one of the most common. Many people can not understand right away that they are sick with mycosis. Moreover, even after the appearance of unpleasant symptoms, some patients do not hurry to the doctor, trying to restore health by self-medication. Starting to take this drug, some even do not know exactly what the ointment is, and how it differs from its counterparts. In order not to harm health, preparations of such action can be used only according to the doctor's prescription.