Termicon cream 1% 15gr

User manual for Termicon cream

You can buy Termicon cream on this page

Composition

1 g of cream contains:
Active ingredient: terbinafine hydrochloride - 10.0 mg
Excipients: cetyl alcohol, stearyl alcohol or cetostearyl alcohol - 80.0 mg, benzyl alcohol - 10.0 mg, cetyl palmitate - 20.0 mg, polysorbate 60 - 61.0 mg, isopropyl myristate - 80.0 mg, sorbitan stearate - 19.0 mg, sodium hydroxide - 1.2 mg, purified water - up to 1000, 0 mg.
Description
White uniform cream with a weak specific smell.
Pharmacotherapeutic group:
Antifungal agent

Pharmacological properties.

Antifungal drug for local use, with a wide range of antifungal activity. In low concentrations, terbinafine has a fungicidal effect against dermatophytes (Trychophyton rubrum, T. mentagrophytes, T.verrucosum, T.violaceum, T.tonsurans, Microsporum canis, Epidermophyton floccosum), molds (for example, Aspergillus, Castororus, optus phytophorum floccosum, mold). (Pityrosporum orbiculare) and yeast fungi (mainly Candida albicans). The activity against the remaining Candida spp. Yeast fungi, depending on their species, can be fungicidal or fungistatic.
Terbinafine specifically alters the early stage of sterol biosynthesis that occurs in fungi. This leads to a deficiency of ergosterol and to the intracellular accumulation of squalene, which causes the death of the fungal cell. The action of terbinafine is carried out by inhibiting the enzyme squalene epoxidase, located on the cell membrane of the fungus.
Terbinafine does not affect the cytochrome P450 system in humans and, accordingly, the metabolism of hormones or other drugs.

Pharmacokinetics.

When applied topically, absorption - less than 5%, has a slight systemic effect.

Indications for use

Prevention and treatment of fungal infections of the skin, including:
    foot mycoses ("fungus" of the foot);
    groin athlete's disease;
    fungal infections of the smooth skin of the body;
    Infections caused by yeast-like fungi of the genus Candida (candidiasis), in particular diaper rash;
    Multicolored (scaly) lichen.

Contraindications

Hypersensitivity to terbinafine or to any component of Termicon cream; breastfeeding period; children's age up to 12 years (for this dosage form).
With caution: hepatic and / or renal failure, alcoholism, inhibition of bone marrow hematopoiesis, tumors, metabolic diseases, occlusive vascular diseases of the limbs.

Use during pregnancy and during breastfeeding

In experimental studies, the teratogenic properties of terbinafine have not been identified. To date, no malformations have been reported with the use of cream with terbinafine.
However, since the clinical experience with the use of terbinafine in the form of cream in pregnant women is very limited, it should not be used unless absolutely necessary. In pregnancy, apply only if the intended benefit to the mother outweighs the potential risk to the fetus. Need to consult a doctor.
Terbinafine is excreted in breast milk, so Termicon cream should not be used for nursing mothers. The infant should not be allowed to come into contact with any surface of the skin treated with the cream.

Dosage and administration

Outwardly.
Adults and children from 12 years old: Clean and dry the affected areas before applying the cream. The cream is applied 1 or 2 times a day with a thin layer on the affected skin and surrounding areas and lightly rubbed. For infections accompanied by diaper rash (under the mammary glands, in the interdigital spaces, between the buttocks, in the groin area), the places of application of the cream can be covered with gauze, especially at night.
The average duration and frequency of use
Ringworm - 1 week - 1 time per day
Ringworm of the trunk, legs, folds - 1 week - 1 time per day
Skin candidiasis - 1-2 weeks - 1 or 2 times a day
Multi-colored lichen - 2 weeks - 1 or 2 times a day
Reducing the severity of clinical manifestations is usually observed in the first days of treatment. In the case of irregular treatment or its premature termination, there is a risk of re-infection.
The dosage regimen of Termicon cream in the elderly does not differ from the above.

Use of the drug in children

The use of this drug in children under 12 years is not recommended.
If there is no improvement after treatment or new symptoms appear, it is necessary to consult a doctor.
Use Termicon cream only according to the method of use and in those doses that are indicated in the instructions. If necessary, please consult a physician before using the drug.

Side effects

In places of application of Termicon cream may appear redness, itching or burning. Allergic reactions.

Overdose with Termicon cream

No cases of drug overdose have been reported. If, by chance, Termicon Cream is ingested, one can expect the development of the same side effects as with an overdose of Termicon tablets (headache, nausea, epigastric pain and dizziness).
Treatment: activated carbon, if necessary - symptomatic supportive therapy.

Interaction with other drugs

Any drug interactions for Termicon cream are not known.

special instructions for Termicon cream

Reducing the severity of clinical manifestations is usually observed in the first days of treatment. In the case of irregular treatment or its premature termination, there is a risk of re-infection.
Termicon cream is for external use only. Avoid contact with eyes, as it may cause irritation. In case of accidental ingestion of Termicon cream in the eyes, they should be immediately washed with running water, and in the case of persistent irritation, you should consult with your doctor.
With the development of allergic reactions necessary to cancel the drug.

Release form

Cream for external use 1% in aluminum tubes of 10 g or 15 g. Each tube with instructions for use is placed in a pack of cardboard.

Storage conditions

Store at a temperature not higher than 30 ° C. Keep out of the reach of children.
Shelf life - 3 years. Do not use beyond the expiration date printed on the package.

Pharmacy sales terms

You don't need a prescription to buy Termicon cream.