Orvirem syrup 2mg/ml 100ml

Orvirem instruction

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Composition

In 5 ml of syrup contains rimantadine hydrochloride - 10 mg, excipients (sugar, water, sodium alginate, E122).

Form of issue

Produced in the form of syrup in flacon 100 ml, in cardboard packs. The syrup has a thick consistency and a pinkish-red color.

pharmachologic effect

Antiviral.

Pharmacodynamics and pharmacokinetics

The active substance rimantadine hydrochloride is in the matrix cells of sodium alginate, which causes the active components to gradually release from the agent. In this case, the toxic effect of rimantadine and the possibility of manifestations of allergic reactions is minimized.
In turn, the active substance blocks the process of fusion of the envelope of the virus with endosomal membranes, the transfer of gene. information from the virus to the cytoplasm of the cell does not occur (the process of transcription of the genome).
The substance stimulates the production of antibodies to fight the virus, catalyzes the processes of induction of interferon. Due to rimantadin, a decrease in the number of cytokines and, as a result, detoxification of the body, decreases the antigen load and inflammation.

Indications for use

Prescribe a drug for children, starting with a year of age
    for the treatment of viral diseases (mainly influenza A);
    prevention of such diseases, including during epidemics, in children's institutions or at home.

Contraindications

Antiviral syrup for children is contraindicated:
    children up to one year;
    with drug allergies to components;
    with thyrotoxicosis;
    pregnancy and lactation;
    with diabetes mellitus;
    diseases of the liver, kidneys.

Side effects

Observed rarely.
But, nevertheless, are possible:
    pain in the epigastric region, diarrhea and flatulence, nausea;
    sleep disturbance, headaches, neuralgia;
    rashes on the skin, asthenia, itching of the skin.

Instructions for Orvirem (Method and dosage)

The drug is administered orally after eating. The maximum daily dose of syrup is 5 mg per kg of body weight.
One teaspoon, as a rule, contains 5 ml of medicine.
Instruction for children in case of prevention:
    children from one year to three are prescribed 10 ml per day (2 tablespoons);
    children from three to seven years - 15 ml;
    children from seven to 14 years - 20 ml.

Instructions for the use of Orvirem for the treatment of viral diseases

At the age of one to three:

    in 1 day - 3 doses of 10 ml;
    at 2, 3 day - 2 admission of 10 ml;
    in day 4 - once 10 ml.

From three to seven years:

    in 1 day - 3 receptions of 15 ml;
    in 2 and 3 - 2 receptions of 15 ml;
    in day 4 - once 15 ml.

Children from 7 to 14 years:

    the first day - 3 doses of 20 ml;
    the second and third - 2 doses of 20 ml;
    the fourth - once 20 ml.

Overdose

No cases have been reported.

Interaction

When combined with epilepsy drugs, consult a specialist.
The drug enhances the effect of caffeine on the central nervous system.
The effectiveness of the drug is reduced when combined with paracetamol and aspirin.

Storage conditions

Inaccessible to children, dark, cool place.
Shelf life - 3 years.

special instructions

In diabetes, it should be borne in mind that the medicine contains a large amount of sugar.

Analogues

Arbidol, anaferol, Tamiflu.

Reviews about Orvirem

Reviews for Orvirem for children. Many parents prefer to use syrup for children to treat influenza, the drug speeds up the healing process, prevents unwanted complications. It is often prescribed by doctors. However, side effects often occur in the form of allergies. Some consider taking a drug to prevent influenza A is inappropriate, giving preference to folk and other ways to strengthen immunity.